Metabolic complications with the use of mTOR inhibitors for cancer therapy.
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T. Choueiri | N. Agarwal | G. Sonpavde | W. Oh | M. Galsky | Jian Ying | K. Boucher | B. Gartrell | Shanthi Sivendran
[1] J. Machiels,et al. Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.
[2] D. Ettinger,et al. A phase 2 study of temsirolimus (CCI‐779) in patients with soft tissue sarcomas , 2011, Cancer.
[3] J. Blay,et al. Results of the phase III, placebo-controlled trial (SUCCEED) evaluating the mTOR inhibitor ridaforolimus (R) as maintenance therapy in advanced sarcoma patients (pts) following clinical benefit from prior standard cytotoxic chemotherapy (CT). , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[4] D. Sabatini,et al. mTOR: from growth signal integration to cancer, diabetes and ageing , 2010, Nature Reviews Molecular Cell Biology.
[5] R. Broaddus,et al. A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma , 2010, Cancer.
[6] S. Dacic,et al. Phase II Study of Everolimus (RAD001) in Previously Treated Small Cell Lung Cancer , 2010, Clinical Cancer Research.
[7] Norbert Hollaender,et al. Phase 3 trial of everolimus for metastatic renal cell carcinoma , 2010, Cancer.
[8] Wolfgang Viechtbauer,et al. Conducting Meta-Analyses in R with the metafor Package , 2010 .
[9] R. Wolff,et al. Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies , 2010, BMC Cancer.
[10] M. Robson,et al. Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] E. Baudin,et al. Daily Oral Everolimus Activity in Patients with Metastatic Pancreatic Neuroendocrine Tumors after Failure of Cytotoxic Chemotherapy: A Phase II Trial , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[12] Eric Sauerbrei,et al. Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[13] D. Moher,et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement , 2009, BMJ.
[14] J. Douketis,et al. The devil is in the detailsor not? A primer on individual patient data meta-analysis , 2009, Annals of Internal Medicine.
[15] R. Greil,et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] R. Amato,et al. A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer , 2009, Cancer.
[17] Jeffrey W. Clark,et al. Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[18] M. Hidalgo,et al. A Randomized, Phase II Trial of Two Dose Levels of Temsirolimus (CCI-779) in Patients with Extensive-Stage Small-Cell Lung Cancer Who Have Responding or Stable Disease after Induction Chemotherapy: A Trial of the Eastern Cooperative Oncology Group (E1500) , 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[19] David McDermott,et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. , 2007, The New England journal of medicine.
[20] Allison Gruner Gandhi,et al. The Devil Is in the Details , 2007, Evaluation review.
[21] G. Pond,et al. A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas , 2006, British Journal of Cancer.
[22] D. Sabatini. mTOR and cancer: insights into a complex relationship , 2006, Nature Reviews Cancer.
[23] Wolfgang Eiermann,et al. Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] B. Scheithauer,et al. Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] Susan M. Chang,et al. Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme , 2005, Investigational New Drugs.
[26] S. Liou,et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[27] G. Smith,et al. Bias in meta-analysis detected by a simple, graphical test , 1997, BMJ.
[28] A R Jadad,et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? , 1996, Controlled clinical trials.
[29] J. Blay,et al. Phase II study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[30] J. Thigpen. Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer , 2012 .
[31] R. Pearson. Everolimus for Advanced Pancreatic Neuroendocrine Tumors , 2011 .
[32] J. Douketis,et al. ACP Journal Club. The devil is in the details...or not? A primer on individual patient data meta-analysis. , 2009, Annals of Internal Medicine.
[33] J. Doroshow,et al. CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium. , 2004, Cancer.