The genetics of mammalian circadian order and disorder: implications for physiology and disease

[1]  Paolo Sassone-Corsi,et al.  The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control , 2008, Cell.

[2]  Florian Kreppel,et al.  SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation , 2008, Cell.

[3]  D. Bechtold,et al.  Setting Clock Speed in Mammals: The CK1ɛ tau Mutation in Mice Accelerates Circadian Pacemakers by Selectively Destabilizing PERIOD Proteins , 2008, Neuron.

[4]  A. Carter,et al.  Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man , 2008, International Journal of Obesity.

[5]  E. Mignot.  Why We Sleep: The Temporal Organization of Recovery , 2008, PLoS biology.

[6]  Daniel Lucas,et al.  Haematopoietic stem cell release is regulated by circadian oscillations , 2008, Nature.

[7]  F. Tamanini,et al.  Phase Resetting of the Mammalian Circadian Clock by DNA Damage , 2008, Current Biology.

[8]  Steven A. Brown,et al.  Molecular insights into human daily behavior , 2008, Proceedings of the National Academy of Sciences.

[9]  Stuart N. Peirson,et al.  Melanopsin: an exciting photopigment , 2008, Trends in Neurosciences.

[10]  R. A. Reid,et al.  Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways , 2007, Science.

[11]  Paolo Sassone-Corsi,et al.  CLOCK-mediated acetylation of BMAL1 controls circadian function , 2007, Nature.

[12]  M. Gordijn,et al.  Epidemiology of the human circadian clock. , 2007, Sleep medicine reviews.

[13]  S. Khorasanizadeh,et al.  Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ , 2007, Nature Structural &Molecular Biology.

[14]  Kathryn Moynihan Ramsey,et al.  High-fat diet disrupts behavioral and molecular circadian rhythms in mice. , 2007, Cell metabolism.

[15]  Mary A. Carskadon,et al.  Circadian Rhythm Sleep Disorders: Part I, Basic Principles, Shift Work and Jet Lag Disorders , 2007 .

[16]  M. Carskadon,et al.  Table of Contents Circadian Rhythm Sleep Disorders: Part Ii, Advanced Sleep Phase Disorder, Delayed Sleep Phase Disorder, Free-running Disorder, and Irregular Sleep-wake Rhythm an American Academy of Sleep Medicine Review Circadian Rhythm Sleep Disorders , 2022 .

[17]  Hanspeter Herzel,et al.  β-TrCP1-Mediated Degradation of PERIOD2 Is Essential for Circadian Dynamics , 2007, Journal of biological rhythms.

[18]  Erik D. Herzog,et al.  Neurons and networks in daily rhythms , 2007, Nature Reviews Neuroscience.

[19]  M. Bihoreau,et al.  Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes , 2007, Proceedings of the National Academy of Sciences.

[20]  D. Gauguier.  Polymorphisms in aryl hydrocarbon receptor nuclear translocator-like (Arntl, Bmal1) are associated with Type 2 diabetes and hypertension , 2007 .

[21]  A. Kohsaka,et al.  The clockwork of metabolism. , 2007, Annual review of nutrition.

[22]  C. Kyriacou,et al.  A Molecular Basis for Natural Selection at the timeless Locus in Drosophila melanogaster , 2007, Science.

[23]  Joseph Fogerty,et al.  Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity , 2007, Proceedings of the National Academy of Sciences.

[24]  Joseph S. Takahashi,et al.  Circadian Mutant Overtime Reveals F-box Protein FBXL3 Regulation of Cryptochrome and Period Gene Expression , 2007, Cell.

[25]  Jiandie D. Lin,et al.  Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism , 2007, Nature.

[26]  Michele Pagano,et al.  SCFFbxl3 Controls the Oscillation of the Circadian Clock by Directing the Degradation of Cryptochrome Proteins , 2007, Science.

[27]  M. Pagano,et al.  The After-Hours Mutant Reveals a Role for Fbxl3 in Determining Mammalian Circadian Period , 2007, Science.

[28]  Francis J. Doyle,et al.  Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network , 2007, Cell.

[29]  Kole T. Roybal,et al.  Mania-like behavior induced by disruption of CLOCK , 2007, Proceedings of the National Academy of Sciences.

[30]  D. Dijk,et al.  PER3 Polymorphism Predicts Sleep Structure and Waking Performance , 2007, Current Biology.

[31]  D. Berson,et al.  Phototransduction in ganglion-cell photoreceptors , 2007, Pflügers Archiv - European Journal of Physiology.

[32]  Takeshi Sakurai,et al.  The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness , 2007, Nature Reviews Neuroscience.

[33]  Erin L. McDearmon,et al.  Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation , 2007, Proceedings of the National Academy of Sciences.

[34]  D. Virshup,et al.  Post-translational modifications regulate the ticking of the circadian clock , 2007, Nature Reviews Molecular Cell Biology.

[35]  Ueli Schibler,et al.  System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock , 2007, PLoS biology.

[36]  Christopher R. Jones,et al.  Modeling of a Human Circadian Mutation Yields Insights into Clock Regulation by PER2 , 2007, Cell.

[37]  A. Bradley,et al.  Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei , 2007, Proceedings of the National Academy of Sciences.

[38]  Ueli Schibler,et al.  Circadian rhythms: mechanisms and therapeutic implications. , 2007, Annual review of pharmacology and toxicology.

[39]  S. Khorasanizadeh,et al.  Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. , 2007, Nature structural & molecular biology.

[40]  Erin L. McDearmon,et al.  Dissecting the Functions of the Mammalian Clock Protein BMAL1 by Tissue-Specific Rescue in Mice , 2006, Science.

[41]  Michael W Young,et al.  Interplay of circadian clocks and metabolic rhythms. , 2006, Annual review of genetics.

[42]  Michelle Y. Cheng,et al.  Attenuated Circadian Rhythms in Mice Lacking the Prokineticin 2 Gene , 2006, The Journal of Neuroscience.

[43]  Hanspeter Herzel,et al.  Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS). , 2006, Genes & development.

[44]  Yoshiyuki Watanabe,et al.  Prospective cohort study of the risk of prostate cancer among rotating-shift workers: findings from the Japan collaborative cohort study. , 2006, American journal of epidemiology.

[45]  Weimin He,et al.  Nuclear Receptor Expression Links the Circadian Clock to Metabolism , 2006, Cell.

[46]  Jay C Dunlap,et al.  The Neurospora Checkpoint Kinase 2: A Regulatory Link Between the Circadian and Cell Cycles , 2006, Science.

[47]  M. Antoch,et al.  Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock. , 2006, Genes & development.

[48]  Daniel B Forger,et al.  An opposite role for tau in circadian rhythms revealed by mathematical modeling. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[49]  S. Gery,et al.  The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells. , 2006, Molecular cell.

[50]  Paolo Sassone-Corsi,et al.  Circadian Regulator CLOCK Is a Histone Acetyltransferase , 2006, Cell.

[51]  S. McKnight,et al.  NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[52]  C. Nievergelt,et al.  Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder , 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[53]  Ueli Schibler,et al.  Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions , 2006, Nature Genetics.

[54]  C. Weitz,et al.  A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity , 2006, Nature Neuroscience.

[55]  C. Saper,et al.  Hypothalamic regulation of sleep and circadian rhythms , 2005, Nature.

[56]  Steven A. Brown,et al.  The Period Length of Fibroblast Circadian Gene Expression Varies Widely among Human Individuals , 2005, PLoS biology.

[57]  E. Wagner,et al.  The Molecular Clock Mediates Leptin-Regulated Bone Formation , 2005, Cell.

[58]  D. Skene,et al.  A single‐nucleotide polymorphism in the 5′‐untranslated region of the hPER2 gene is associated with diurnal preference , 2005, Journal of sleep research.

[59]  Francine Laden,et al.  Night work and breast cancer risk: a systematic review and meta-analysis. , 2005, European journal of cancer.

[60]  S. Shimba,et al.  Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[61]  J. Harper,et al.  SCFβ-TRCP Controls Clock-dependent Transcription via Casein Kinase 1-dependent Degradation of the Mammalian Period-1 (Per1) Proteinm* , 2005, Journal of Biological Chemistry.

[62]  P. Hardin,et al.  Circadian rhythms from multiple oscillators: lessons from diverse organisms , 2005, Nature Reviews Genetics.

[63]  J. Takahashi,et al.  Regulation of dopaminergic transmission and cocaine reward by the Clock gene. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[64]  Fred W. Turek,et al.  Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice , 2005, Science.

[65]  J. Takahashi,et al.  Circadian Clock Genes as Modulators of Sensitivity to Genotoxic Stress , 2005, Cell cycle.

[66]  Giulio Tononi,et al.  Reduced sleep in Drosophila Shaker mutants , 2005, Nature.

[67]  Aziz Sancar,et al.  Coupling of Human Circadian and Cell Cycles by the Timeless Protein , 2005, Molecular and Cellular Biology.

[68]  S. Maret,et al.  Genetics of normal and pathological sleep in humans. , 2005, Sleep medicine reviews.

[69]  F. Turek,et al.  Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation. , 2005, Sleep.

[70]  Peter Woolf,et al.  Control of Mammalian Circadian Rhythm by CKIε-Regulated Proteasome-Mediated PER2 Degradation , 2005, Molecular and Cellular Biology.

[71]  Ying Xu,et al.  Functional consequences of a CKIδ mutation causing familial advanced sleep phase syndrome , 2005, Nature.

[72]  J. Takahashi,et al.  Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[73]  C. Nievergelt,et al.  Examination of the clock gene Cryptochrome 1 in bipolar disorder: mutational analysis and absence of evidence for linkage or association , 2005, Psychiatric genetics.

[74]  R. Colman,et al.  Progressive arthropathy in mice with a targeted disruption of the Mop3/Bmal‐1 locus , 2005, Genesis.

[75]  Rae Silver,et al.  Orchestrating time: arrangements of the brain circadian clock , 2005, Trends in Neurosciences.

[76]  K. Mishima,et al.  The 3111T/C polymorphism of hClock is associated with evening preference and delayed sleep timing in a Japanese population sample , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[77]  K. Hornik,et al.  No association of clock gene T3111C polymorphism and affective disorders , 2005, European Neuropsychopharmacology.

[78]  Peter Woolf,et al.  Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. , 2005, Molecular and cellular biology.

[79]  Nelson A. M. Lemos,et al.  Association of the length polymorphism in the human Per3 gene with the delayed sleep-phase syndrome: does latitude have an influence upon it? , 2005, Sleep.

[80]  Gunter Schumann,et al.  The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption , 2005, Nature Medicine.

[81]  Steve A. Kay,et al.  Bioluminescence Imaging of Individual Fibroblasts Reveals Persistent, Independently Phased Circadian Rhythms of Clock Gene Expression , 2004, Current Biology.

[82]  C. Thummel,et al.  Faculty Opinions recommendation of Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells. , 2004 .

[83]  K. Spiegel,et al.  Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite , 2004, Annals of Internal Medicine.

[84]  T. Young,et al.  Short Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index , 2004, PLoS medicine.

[85]  Felix Naef,et al.  Circadian Gene Expression in Individual Fibroblasts Cell-Autonomous and Self-Sustained Oscillators Pass Time to Daughter Cells , 2004, Cell.

[86]  Satchidananda Panda,et al.  BMAL1 and CLOCK, Two Essential Components of the Circadian Clock, Are Involved in Glucose Homeostasis , 2004, PLoS biology.

[87]  N. Kajimura,et al.  A Missense Variation in Human Casein Kinase I Epsilon Gene that Induces Functional Alteration and Shows an Inverse Association with Circadian Rhythm Sleep Disorders , 2004, Neuropsychopharmacology.

[88]  J. Takahashi,et al.  Mammalian circadian biology: elucidating genome-wide levels of temporal organization. , 2004, Annual review of genomics and human genetics.

[89]  L. Miraglia,et al.  A Functional Genomics Strategy Reveals Rora as a Component of the Mammalian Circadian Clock , 2004, Neuron.

[90]  Cheng Chi Lee,et al.  Reciprocal regulation of haem biosynthesis and the circadian clock in mammals , 2004, Nature.

[91]  Ook Joon Yoo,et al.  PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[92]  A. Sehgal,et al.  Why a fly? Using Drosophila to understand the genetics of circadian rhythms and sleep. , 2004, Sleep.

[93]  S. Yamaguchi,et al.  Control Mechanism of the Circadian Clock for Timing of Cell Division in Vivo , 2003, Science.

[94]  A. B. Reddy,et al.  A clockwork web: circadian timing in brain and periphery, in health and disease , 2003, Nature Reviews Neuroscience.

[95]  Josephine Arendt,et al.  A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. , 2003, Sleep.

[96]  Patricia Wood,et al.  Circadian Timing in Cancer Treatment: The Biological Foundation for an Integrative Approach , 2003, Integrative cancer therapies.

[97]  T. Ebisawa,et al.  Two pedigrees of familial advanced sleep phase syndrome in Japan. , 2003, Sleep.

[98]  C. Pollak,et al.  The role of actigraphy in the study of sleep and circadian rhythms. , 2003, Sleep.

[99]  T. Paunio,et al.  Circadian Clock-Related Polymorphisms in Seasonal Affective Disorder and their Relevance to Diurnal Preference , 2003, Neuropsychopharmacology.

[100]  A. Wirz-Justice,et al.  Life between Clocks: Daily Temporal Patterns of Human Chronotypes , 2003, Journal of biological rhythms.

[101]  Steven M. Reppert,et al.  Rhythmic histone acetylation underlies transcription in the mammalian circadian clock , 2003, Nature.

[102]  P. Franken,et al.  A role for cryptochromes in sleep regulation , 2002, BMC Neuroscience.

[103]  Josephine Arendt,et al.  The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects , 2002, Journal of sleep research.

[104]  S. McKnight,et al.  NPAS2: A Gas-Responsive Transcription Factor , 2002, Science.

[105]  Peng Huang,et al.  The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo , 2002, Cell.

[106]  Steven A. Brown,et al.  Rhythms of Mammalian Body Temperature Can Sustain Peripheral Circadian Clocks , 2002, Current Biology.

[107]  Sumio Sugano,et al.  A transcription factor response element for gene expression during circadian night , 2002, Nature.

[108]  Ueli Schibler,et al.  The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator , 2002, Cell.

[109]  Michelle Y. Cheng,et al.  Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus , 2002, Nature.

[110]  B. H. Miller,et al.  Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock , 2002, Cell.

[111]  Kai-Florian Storch,et al.  Extensive and divergent circadian gene expression in liver and heart , 2002, Nature.

[112]  Francis Lévi,et al.  Host circadian clock as a control point in tumor progression. , 2002, Journal of the National Cancer Institute.

[113]  N. Kajimura,et al.  Mutation screening of the human Clock gene in circadian rhythm sleep disorders , 2002, Psychiatry Research.

[114]  Emmanuel Mignot,et al.  The role of hypocretins (orexins) in sleep regulation and narcolepsy. , 2002, Annual review of neuroscience.

[115]  Jared Rutter,et al.  Metabolism and the control of circadian rhythms. , 2002, Annual review of biochemistry.

[116]  Steven M. Reppert,et al.  Posttranslational Mechanisms Regulate the Mammalian Circadian Clock , 2001, Cell.

[117]  C. Weitz,et al.  Regulation of Daily Locomotor Activity and Sleep by Hypothalamic EGF Receptor Signaling , 2001, Science.

[118]  S H Jones,et al.  Circadian rhythms, multilevel models of emotion and bipolar disorder--an initial step towards integration? , 2001, Clinical psychology review.

[119]  F Laden,et al.  Rotating night shifts and risk of breast cancer in women participating in the nurses' health study. , 2001, Journal of the National Cancer Institute.

[120]  C A Czeisler,et al.  Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase. , 2001, Behavioral neuroscience.

[121]  Jared Rutter,et al.  Regulation of Clock and NPAS2 DNA Binding by the Redox State of NAD Cofactors , 2001, Science.

[122]  M. Dubocovich,et al.  Familial advanced sleep phase syndrome. , 2001, Archives of neurology.

[123]  Y Sakaki,et al.  Entrainment of the circadian clock in the liver by feeding. , 2001, Science.

[124]  Christopher R. Jones,et al.  An hPer2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome , 2001, Science.

[125]  J. Kelsoe,et al.  A PEDIGREE OF ONE FAMILY WITH DELAYED SLEEP PHASE SYNDROME , 2001, Chronobiology international.

[126]  John B. Hogenesch,et al.  Mop3 Is an Essential Component of the Master Circadian Pacemaker in Mammals , 2000, Cell.

[127]  F. Fleury-Olela,et al.  Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. , 2000, Genes & development.

[128]  Fred W. Turek,et al.  The Circadian Clock Mutation Alters Sleep Homeostasis in the Mouse , 2000, The Journal of Neuroscience.

[129]  Steven A. Brown,et al.  Resetting of circadian time in peripheral tissues by glucocorticoid signaling. , 2000, Science.

[130]  J. Smoller,et al.  Genetic polymorphism at the CLOCK gene locus and major depression. , 2000, American journal of medical genetics.

[131]  Y Sakaki,et al.  Resetting central and peripheral circadian oscillators in transgenic rats. , 2000, Science.

[132]  J. Takahashi,et al.  Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. , 2000, Science.

[133]  A. Loudon,et al.  Postnatal growth rate and gonadal development in circadian tau mutant hamsters reared in constant dim red light. , 2000, Journal of reproduction and fertility.

[134]  L. Lopez-Molina,et al.  The Transcription Factor DBP Affects Circadian Sleep Consolidation and Rhythmic EEG Activity , 2000, The Journal of Neuroscience.

[135]  P. Hauri,et al.  An American Academy of Sleep Medicine Review , 2000 .

[136]  Christopher R. Jones,et al.  Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans , 1999, Nature Medicine.

[137]  R. Kronauer,et al.  Stability, precision, and near-24-hour period of the human circadian pacemaker. , 1999, Science.

[138]  P. Achermann,et al.  Sleep homeostasis and models of sleep regulation. , 1999, Journal of biological rhythms.

[139]  D. P. King,et al.  A CLOCK polymorphism associated with human diurnal preference. , 1998, Sleep.

[140]  A. Loudon,et al.  Metabolic Rate Changes Proportionally to Circadian Frequency in tau Mutant Syrian Hamsters , 1997, Journal of biological rhythms.

[141]  C S Pittendrigh,et al.  Temporal organization: reflections of a Darwinian clock-watcher. , 1993, Annual review of physiology.

[142]  J. Gillin,et al.  Circadian rhythm disturbances in manic-depressive illness. , 1983, Federation proceedings.

[143]  N. H. Rubin,et al.  Circadian rhythm. , 1983, The Journal of investigative dermatology.

[144]  J. Horne,et al.  A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. , 1976, International journal of chronobiology.

[145]  J. Aschoff,et al.  Circadian Rhythms in Man , 1965, Science.