Genomic Approaches to Hypertension

[1]  N. Powe,et al.  Race and Genetic Ancestry in Medicine - A Time for Reckoning with Racism. , 2021, The New England journal of medicine.

[2]  Tom R. Gaunt,et al.  Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals , 2020, Nature Genetics.

[3]  Byron C. Jaeger,et al.  Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018. , 2020, JAMA.

[4]  Craig M. Hales,et al.  Trends in Obesity Prevalence by Race and Hispanic Origin-1999-2000 to 2017-2018. , 2020, JAMA.

[5]  C. Blackmore,et al.  Disparities in Incidence of COVID-19 Among Underrepresented Racial/Ethnic Groups in Counties Identified as Hotspots During June 5–18, 2020 — 22 States, February–June 2020 , 2020, MMWR. Morbidity and mortality weekly report.

[6]  E. Çakıcı,et al.  Clinical assessment of primary and secondary hypertension in children and adolescents. , 2020, Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.

[7]  Qifu Li,et al.  Genetic screening for monogenic hypertension in hypertensive individuals in a clinical setting , 2020, Journal of Medical Genetics.

[8]  S. Padmanabhan,et al.  Genomics of Blood Pressure and Hypertension: Extending the Mosaic Theory Toward Stratification , 2020, The Canadian journal of cardiology.

[9]  M. Sims,et al.  Optimism and cardiovascular health among African Americans in the Jackson Heart Study. , 2019, Preventive medicine.

[10]  P. Munroe,et al.  Over 1,000 genetic loci influencing blood pressure with multiple systems and tissues implicated. , 2019, Human molecular genetics.

[11]  R. Raina,et al.  Overview of Monogenic or Mendelian Forms of Hypertension , 2019, Front. Pediatr..

[12]  Sara M. Willems,et al.  Trans-ethnic association study of blood pressure determinants in over 750,000 individuals , 2018, Nature Genetics.

[13]  Andrew D. Johnson,et al.  Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits , 2018, Nature Genetics.

[14]  V. Torres,et al.  Recent Advances in the Management of Autosomal Dominant Polycystic Kidney Disease. , 2018, Clinical journal of the American Society of Nephrology : CJASN.

[15]  Francesca N. Delling,et al.  Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association , 2018, Circulation.

[16]  I. Mozoș,et al.  Two mutations in the thiazide-sensitive NaCl co-transporter gene in a Romanian Gitelman syndrome patient: case report , 2018, Therapeutics and clinical risk management.

[17]  David F Rodriguez-Buritica,et al.  Monogenic Hypertension in Children: A Review With Emphasis on Genetics. , 2017, Advances in chronic kidney disease.

[18]  G. Ehret.  Next Steps for Gene Identification in Primary Hypertension Genomics. , 2017, Hypertension.

[19]  R. Holman,et al.  Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5: A Systematic Review and Meta-analysis , 2017, JAMA internal medicine.

[20]  He Zhang,et al.  Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension , 2016, Nature Genetics.

[21]  Claude Bouchard,et al.  Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci , 2016, Nature Genetics.

[22]  Jing He,et al.  Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation , 2015, Nature Genetics.

[23]  T. Kanda,et al.  Peroxisome proliferator-activated receptors for hypertension. , 2014, World journal of cardiology.

[24]  T. Rice,et al.  Genome-Wide Linkage and Regional Association Study of Blood Pressure Response to the Cold Pressor Test in Han Chinese: The Genetic Epidemiology Network of Salt Sensitivity Study , 2014, Circulation. Cardiovascular genetics.

[25]  E. Boerwinkle,et al.  Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program. , 2014, Atherosclerosis.

[26]  H. Keen,et al.  Dominant negative PPARγ promotes atherosclerosis, vascular dysfunction, and hypertension through distinct effects in endothelium and vascular muscle. , 2013, American journal of physiology. Regulatory, integrative and comparative physiology.

[27]  Kathleen F. Kerr,et al.  Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. , 2013, Heart rhythm.

[28]  Michael E. Hall,et al.  Hypertension: physiology and pathophysiology. , 2012, Comprehensive Physiology.

[29]  M. Mohaupt,et al.  Monogenic forms of hypertension , 2012, European Journal of Pediatrics.

[30]  X. Estivill,et al.  KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron , 2012, Nature Genetics.

[31]  Jai Radhakrishnan,et al.  Mutations in Kelch-like 3 and Cullin 3 cause hypertension and electrolyte abnormalities , 2012, Nature.

[32]  D. Bluemke,et al.  Association of self-reported race/ethnicity and genetic ancestry with arterial elasticity: the Multi-Ethnic Study of Atherosclerosis (MESA). , 2011, Journal of the American Society of Hypertension : JASH.

[33]  Tom R. Gaunt,et al.  Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk , 2011, Nature.

[34]  P. Doris.  The genetics of blood pressure and hypertension: the role of rare variation. , 2011, Cardiovascular therapeutics.

[35]  Judy H. Cho,et al.  Finding the missing heritability of complex diseases , 2009, Nature.

[36]  Andrew D. Johnson,et al.  Genome-wide association study of blood pressure and hypertension , 2009, Nature Genetics.

[37]  P. O’Reilly,et al.  Eight blood pressure loci identified by genome-wide association study of 34,433 people of European ancestry , 2009, Nature genetics.

[38]  A. Rodgers,et al.  Global burden of blood-pressure-related disease, 2001 , 2008, The Lancet.

[39]  Hongyu Zhao,et al.  Rare independent mutations in renal salt handling genes contribute to blood pressure variation , 2008, Nature Genetics.

[40]  A. Deng.  Genetic basis of polygenic hypertension. , 2007, Human molecular genetics.

[41]  A. Benetos,et al.  HEREDITARY AND ENVIRONMENTAL INFLUENCES ON ARTERIAL FUNCTION , 2007, Clinical and experimental pharmacology & physiology.

[42]  Simon C. Potter,et al.  Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.

[43]  S. Turner,et al.  Monogenic forms of low-renin hypertension , 2006, Nature Clinical Practice Nephrology.

[44]  C. McCulloch,et al.  Elevated blood pressure and risk of end-stage renal disease in subjects without baseline kidney disease. , 2005, Archives of internal medicine.

[45]  R. Collins,et al.  Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies , 2002, The Lancet.

[46]  Ali G. Gharavi,et al.  Molecular Mechanisms of Human Hypertension , 2001, Cell.

[47]  E. Lander,et al.  An integrated genetic linkage map of the laboratory rat , 1998, Mammalian Genome.

[48]  R. Lifton.  Molecular Genetics of Human Blood Pressure Variation , 1996, Science.

[49]  P Whelton,et al.  Trends in the prevalence, awareness, treatment, and control of hypertension in the adult US population. Data from the health examination surveys, 1960 to 1991. , 1995, Hypertension.

[50]  Eric S. Lander,et al.  Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat , 1991, Cell.

[51]  T. Kurtz,et al.  Cosegregation of Blood Pressure with a Kallikrein Gene Family Polymorphism , 1991, Hypertension.

[52]  D. Ganten,et al.  Structural alterations of the renin gene in stroke-prone spontaneously hypertensive rats: examination of genotype-phenotype correlations. , 1990, Journal of hypertension.

[53]  T. Kurtz,et al.  Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure. , 1990, The Journal of clinical investigation.

[54]  L. Tsui,et al.  Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. , 1989, Science.

[55]  N. Poulter,et al.  Blood pressure and its correlates in an African tribe in urban and rural environments. , 1984, Journal of epidemiology and community health.

[56]  K. Okamoto,et al.  Development of a strain of spontaneously hypertensive rats. , 1963, Japanese circulation journal.

[57]  P. D. Oldham,et al.  The Hereditary Factor in Arterial Blood-pressure , 1963, British medical journal.

[58]  J. Thoday,et al.  Location of Polygenes , 1961, Nature.

[59]  E. Levtchenko,et al.  Orphanet Journal of Rare Diseases BioMed Central Review , 2008 .

[60]  E S Lander,et al.  Mapping complex genetic traits in humans: new methods using a complete RFLP linkage map. , 1986, Cold Spring Harbor symposia on quantitative biology.