EFFECTS OF TAURINE AND HOMOCYSTEINE ON CALCIUM HOMEOSTASIS AND HYDROGEN PEROXIDE AND SUPEROXIDE ANIONS IN RAT MYOCARDIAL MITOCHONDRIA

1. Taurine and homocysteine are metabolites of methionine. Hyperhomocysteinaemia is one of the risk factors for cardiovascular disease. Although taurine may be a cardiovascular cytoprotective substance, we hypothesized that it may antagonize the effects of homocysteine on myocardial mitochondrial function.

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