Pruning hypothesis comes of age

The idea that disrupted pruning of neuronal connections in the brain during adolescence is a cause of schizophrenia was proposed in 1983. This proved prescient, as subsequent imaging, genetic and molecular research has shown. The idea that disrupted pruning of neuronal connections in the brain during adolescence is a cause of schizophrenia was proposed in 1983. This proved prescient, as subsequent imaging, genetic and molecular research has shown.

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