A-to-I editing of coding and non-coding RNAs by ADARs
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[1] Fritz J Sedlazeck,et al. Adenosine deaminases that act on RNA induce reproducible changes in abundance and sequence of embryonic miRNAs , 2012, Genome research.
[2] Jack F Kirsch,et al. Autoinhibition of human dicer by its internal helicase domain. , 2008, Journal of molecular biology.
[3] T. Dawson,et al. Regulation of alternative splicing by RNA editing , 1999, Nature.
[4] A. Hatzigeorgiou,et al. Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs , 2007, Science.
[5] T. Matise,et al. Widespread RNA editing of embedded alu elements in the human transcriptome. , 2004, Genome research.
[6] P. Seeburg,et al. Liver Disintegration in the Mouse Embryo Caused by Deficiency in the RNA-editing Enzyme ADAR1* , 2004, Journal of Biological Chemistry.
[7] Angela Gallo,et al. A-to-I RNA editing: the "ADAR" side of human cancer. , 2012, Seminars in cell & developmental biology.
[8] P. Seeburg,et al. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels , 1991, Cell.
[9] S. Orkin,et al. Corrigendum: ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling , 2009, Nature Immunology.
[10] T. Shimokawa,et al. RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling , 2013, RNA biology.
[11] B. Bass,et al. Inositol Hexakisphosphate Is Bound in the ADAR2 Core and Required for RNA Editing , 2005, Science.
[12] Peter H. Seeburg,et al. A-to-I RNA Editing: Effects on Proteins Key to Neural Excitability , 2012, Neuron.
[13] M. Sakurai,et al. Antagonistic and stimulative roles of ADAR1 in RNA silencing , 2013, RNA biology.
[14] K. Nishikura,et al. RNA Binding-independent Dimerization of Adenosine Deaminases Acting on RNA and Dominant Negative Effects of Nonfunctional Subunits on Dimer Functions* , 2007, Journal of Biological Chemistry.
[15] Brent A. Shepherd,et al. Effects of ADARs on small RNA processing pathways in C. elegans , 2012, Genome research.
[16] C. Smith,et al. Specific cleavage of hyper‐edited dsRNAs , 2001, The EMBO journal.
[17] K. Wells,et al. Modulation of RNA editing by functional nucleolar sequestration of ADAR2 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[18] K. A. Lehmann,et al. The importance of internal loops within RNA substrates of ADAR1. , 1999, Journal of molecular biology.
[19] David Gacquer,et al. Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome , 2015, bioRxiv.
[20] H. Ueda,et al. Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome. , 2010, Nature chemical biology.
[21] R. Reenan,et al. RNA editing in regulating gene expression in the brain. , 2008, Biochimica et biophysica acta.
[22] S. Tsao,et al. Perturbation of biogenesis and targeting of Epstein-Barr virus-encoded miR-BART3 microRNA by adenosine-to-inosine editing. , 2013, The Journal of general virology.
[23] A. Scadden,et al. Tudor-SN and ADAR1 are components of cytoplasmic stress granules. , 2012, RNA.
[24] B. Sakmann,et al. Determinants of ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: Diversity by RNA editing , 1993, Neuron.
[25] Patrice Vitali,et al. dsRNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis , 2013 .
[26] C. Nusbaum,et al. Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. , 2010, Genes & development.
[27] Brenda L Bass,et al. Mutations in RNAi Rescue Aberrant Chemotaxis of ADAR Mutants , 2003, Science.
[28] Edwin Sandanaraj,et al. Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells. , 2012, The Journal of clinical investigation.
[29] F. Locatelli,et al. ADARs and the Balance Game between Virus Infection and Innate Immune Cell Response. , 2015, Current issues in molecular biology.
[30] K. Nishikura,et al. Dysregulated Editing of Serotonin 2C Receptor mRNAs Results in Energy Dissipation and Loss of Fat Mass , 2008, The Journal of Neuroscience.
[31] John H Livingston,et al. Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature , 2012, Nature Genetics.
[32] R. Emeson,et al. Regulation of serotonin-2C receptor G-protein coupling by RNA editing , 1997, Nature.
[33] Axel Brennicke,et al. RNA editing in plants and its evolution. , 2013, Annual review of genetics.
[34] S. Maas,et al. Identification of a selective nuclear import signal in adenosine deaminases acting on RNA , 2009, Nucleic acids research.
[35] Sheila S. David,et al. RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1 , 2010, Proceedings of the National Academy of Sciences.
[36] V. Kim,et al. Regulation of microRNA biogenesis , 2014, Nature Reviews Molecular Cell Biology.
[37] A. Scadden. The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage , 2005, Nature Structural &Molecular Biology.
[38] M. Jantsch,et al. RNA-Regulated Interaction of Transportin-1 and Exportin-5 with the Double-Stranded RNA-Binding Domain Regulates Nucleocytoplasmic Shuttling of ADAR1 , 2009, Molecular and Cellular Biology.
[39] M. Carmo-Fonseca,et al. Dynamic association of RNA-editing enzymes with the nucleolus , 2003, Journal of Cell Science.
[40] R. Emeson,et al. Editing of neurotransmitter receptor and ion channel RNAs in the nervous system. , 2012, Current topics in microbiology and immunology.
[41] Yukio Kawahara,et al. RNA editing of the microRNA‐151 precursor blocks cleavage by the Dicer–TRBP complex , 2007, EMBO reports.
[42] D. Feldmeyer,et al. Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2 , 2000, Nature.
[43] Kol Jia Yong,et al. A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma , 2013, Gut.
[44] B. Bass,et al. RNA editing by ADARs is important for normal behavior in Caenorhabditis elegans , 2002, The EMBO journal.
[45] K. Nishikura,et al. A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains. , 2000, RNA.
[46] J. Schachter,et al. A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme , 2015, Oncotarget.
[47] J. Mendell,et al. MicroRNAs in Stress Signaling and Human Disease , 2012, Cell.
[48] I. Mian,et al. A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[49] M. Weiss,et al. Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene* , 2004, Journal of Biological Chemistry.
[50] HaroldC. Smith,et al. Functions and regulation of the APOBEC family of proteins. , 2012, Seminars in cell & developmental biology.
[51] Ramana V. Davuluri,et al. ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing , 2013, Cell.
[52] Zuo Zhang,et al. The Fate of dsRNA in the Nucleus A p54nrb-Containing Complex Mediates the Nuclear Retention of Promiscuously A-to-I Edited RNAs , 2001, Cell.
[53] P. Seeburg,et al. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases , 2006, Nature Structural &Molecular Biology.
[54] W. I. Mohamed,et al. A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1 , 2014, Proceedings of the National Academy of Sciences.
[55] G. Church,et al. Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing , 2009, Science.
[56] Wenwei Zhang,et al. Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome , 2012, Nature Biotechnology.
[57] R. Emeson,et al. Altered RNA Editing in Mice Lacking ADAR2 Autoregulation , 2006, Molecular and Cellular Biology.
[58] C. Samuel,et al. ADARs: viruses and innate immunity. , 2012, Current topics in microbiology and immunology.
[59] Shahar Alon,et al. Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma , 2014, Genome Biology.
[60] T. Horikawa,et al. Ten novel mutations of the ADAR1 gene in Japanese patients with dyschromatosis symmetrica hereditaria. , 2007, The Journal of investigative dermatology.
[61] R. Braun,et al. Distribution of Tenr, an RNA-binding protein, in a lattice-like network within the spermatid nucleus in the mouse. , 1995, Biology of reproduction.
[62] K. Nishikura. Functions and regulation of RNA editing by ADAR deaminases. , 2010, Annual review of biochemistry.
[63] Zuo Zhang,et al. Vigilins Bind to Promiscuously A-to-I-Edited RNAs and Are Involved in the Formation of Heterochromatin , 2005, Current Biology.
[64] P. Seeburg,et al. RNA editing of AMPA receptor subunit GluR-B: A base-paired intron-exon structure determines position and efficiency , 1993, Cell.
[65] A. Lin,et al. c-Jun Amino-Terminal Kinase-1 Mediates Glucose-Responsive Upregulation of the RNA Editing Enzyme ADAR2 in Pancreatic Beta-Cells , 2012, PloS one.
[66] T. Cheng,et al. ADAR1 is required for hematopoietic progenitor cell survival via RNA editing , 2009, Proceedings of the National Academy of Sciences.
[67] J. E. Smith,et al. A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[68] Brigitta B. Gundersen,et al. Functional relevance of serotonin 2C receptor mRNA editing in antidepressant- and anxiety-like behaviors , 2010, Neuropharmacology.
[69] Michael Q. Zhang,et al. Regulating Gene Expression through RNA Nuclear Retention , 2005, Cell.
[70] Jun Zhang,et al. ADAR1 is required for differentiation and neural induction by regulating microRNA processing in a catalytically independent manner , 2015, Cell Research.
[71] J. Kjems,et al. CRM1 Mediates the Export of ADAR1 through a Nuclear Export Signal within the Z-DNA Binding Domain , 2001, Molecular and Cellular Biology.
[72] J. Issa,et al. Enrichment for Histone H3 Lysine 9 Methylation at Alu Repeats in Human Cells* , 2003, Journal of Biological Chemistry.
[73] Zipora Y. Fligelman,et al. Systematic identification of abundant A-to-I editing sites in the human transcriptome , 2004, Nature Biotechnology.
[74] Ayelet T. Lamm,et al. Competition between ADAR and RNAi pathways for an extensive class of RNA targets , 2011, Nature Structural &Molecular Biology.
[75] S. Heinemann,et al. Generation and Analysis of GluR5(Q636R) Kainate Receptor Mutant Mice , 1999, The Journal of Neuroscience.
[76] P. Silver,et al. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain , 2005, BMC Developmental Biology.
[77] Joshua J C Rosenthal,et al. The emerging role of RNA editing in plasticity , 2015, The Journal of Experimental Biology.
[78] T Kuner,et al. Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. , 1994, Science.
[79] F. Nielsen,et al. Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain. , 2006, RNA.
[80] I. Gromova,et al. Human BLCAP transcript: new editing events in normal and cancerous tissues , 2009, International journal of cancer.
[81] K. Nishikura,et al. Human endonuclease V is a ribonuclease specific for inosine-containing RNA , 2013, Nature Communications.
[82] Jin Billy Li,et al. Accurate identification of human Alu and non-Alu RNA editing sites , 2012, Nature Methods.
[83] Richard Wooster,et al. A survey of RNA editing in human brain. , 2004, Genome research.
[84] B. Bass. Double-Stranded RNA as a Template for Gene Silencing , 2000, Cell.
[85] S. Heinemann,et al. Ca2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[86] C. Croce,et al. miRNAs, Cancer, and Stem Cell Division , 2005, Cell.
[87] Erez Y. Levanon,et al. A genome-wide map of hyper-edited RNA reveals numerous new sites , 2014, Nature Communications.
[88] Eli Eisenberg,et al. Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors. , 2015, Cell reports.
[89] R. Emeson,et al. Functions and mechanisms of RNA editing. , 2000, Annual review of genetics.
[90] P. Seeburg,et al. RED2, a Brain-specific Member of the RNA-specific Adenosine Deaminase Family* , 1996, The Journal of Biological Chemistry.
[91] Y. Yoshida,et al. Ca2+-Permeable AMPA Receptors Regulate Growth of Human Glioblastoma via Akt Activation , 2007, The Journal of Neuroscience.
[92] Wenjing Zhang,et al. Origins and evolution of ADAR‐mediated RNA editing , 2009, IUBMB life.
[93] Brenda L. Bass,et al. An unwinding activity that covalently modifies its double-stranded RNA substrate , 1988, Cell.
[94] Alexander Rich,et al. Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome , 2004, PLoS biology.
[95] A. Scadden. Inosine-Containing dsRNA Binds a Stress-Granule-like Complex and Downregulates Gene Expression In trans , 2007, Molecular cell.
[96] P. Seeburg,et al. Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2 , 2010, The Journal of Neuroscience.
[97] K. A. Lehmann,et al. Double-stranded RNA adenosine deaminases ADAR1 and ADAR2 have overlapping specificities. , 2000, Biochemistry.
[98] C. Samuel,et al. Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[99] Jin Billy Li,et al. Edinburgh Research Explorer Identifying Rna Editing Sites Using Rna Sequencing Data Alone , 2022 .
[100] K. Nishikura,et al. Substrate specificity of the dsRNA unwinding/modifying activity. , 1991, The EMBO journal.
[101] C. Samuel,et al. Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase , 1995, Molecular and cellular biology.
[102] Emery N. Brown,et al. Comparative RNA Editing in Autistic and Neurotypical Cerebella , 2012, Molecular Psychiatry.
[103] M. O’Connell,et al. RNA editing by mammalian ADARs. , 2011, Advances in genetics.
[104] P. L. Peng,et al. ADAR2-Dependent RNA Editing of AMPA Receptor Subunit GluR2 Determines Vulnerability of Neurons in Forebrain Ischemia , 2006, Neuron.
[105] P. Seeburg,et al. A mammalian RNA editing enzyme , 1996, Nature.
[106] M. Hallegger,et al. Nucleocytoplasmic distribution of human RNA-editing enzyme ADAR1 is modulated by double-stranded RNA-binding domains, a leucine-rich export signal, and a putative dimerization domain. , 2002, Molecular biology of the cell.
[107] Helene Wahlstedt,et al. Adenosine-to-Inosine RNA Editing Affects Trafficking of the γ-Aminobutyric Acid Type A (GABAA) Receptor* , 2010, The Journal of Biological Chemistry.
[108] A. Hatzigeorgiou,et al. Editing of Epstein-Barr Virus-encoded BART6 MicroRNAs Controls Their Dicer Targeting and Consequently Affects Viral Latency* , 2010, The Journal of Biological Chemistry.
[109] G. Carmichael,et al. Alu element‐mediated gene silencing , 2008, The EMBO journal.
[110] John M. Murray,et al. Requirement of Dimerization for RNA Editing Activity of Adenosine Deaminases Acting on RNA* , 2003, The Journal of Biological Chemistry.
[111] Izumi V. Hinkson,et al. RNA Editing of Androgen Receptor Gene Transcripts in Prostate Cancer Cells* , 2008, Journal of Biological Chemistry.
[112] G. Carmichael,et al. On the mechanism of induction of heterochromatin by the RNA-binding protein vigilin. , 2008, RNA.
[113] Leilei Chen,et al. Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma , 2013, Nature Medicine.
[114] Brenda L. Bass,et al. A developmentally regulated activity that unwinds RNA duplexes , 1987, Cell.
[115] Ichiro Kanazawa,et al. Glutamate receptors: RNA editing and death of motor neurons , 2004, Nature.
[116] M. O’Connell,et al. Editing independent effects of ADARs on the miRNA/siRNA pathways , 2009, The EMBO journal.
[117] Kazuko Nishikura,et al. Adenosine-to-inosine RNA editing and human disease , 2013, Genome Medicine.
[118] Leng Han,et al. The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers. , 2015, Cancer cell.
[119] Eli Eisenberg,et al. RNA-editing-mediated exon evolution , 2007, Genome Biology.
[120] Shahar Alon,et al. Systematic identification of edited microRNAs in the human brain , 2012, Genome research.
[121] Aamira Tariq,et al. Transcript Diversification in the Nervous System: A to I RNA Editing in CNS Function and Disease Development , 2012, Front. Neurosci..
[122] J. Kjems,et al. CRM 1 Mediates the Export of ADAR 1 through a Nuclear Export Signal within the Z-DNA Binding Domain , 2001 .
[123] Xinshu Xiao,et al. Genomic Analysis of ADAR1 Binding and its Involvement in Multiple RNA Processing Pathways , 2015, Nature Communications.
[124] R. Aphasizhev,et al. Mitochondrial RNA processing in trypanosomes. , 2011, Research in microbiology.
[125] Erez Y. Levanon,et al. Evolutionarily conserved human targets of adenosine to inosine RNA editing , 2005, Nucleic acids research.
[126] Robert A. Martienssen,et al. RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond , 2013, Nature Reviews Genetics.
[127] G. Del Sal,et al. Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects , 2011, The EMBO journal.
[128] B. Roth,et al. Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader–Willi syndrome , 2010, Neurobiology of Disease.
[129] P. Seeburg,et al. RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself , 2015, Science.
[130] F. Allain,et al. Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs. , 2006, Structure.
[131] G. Carmichael,et al. Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA. , 2009, Molecular cell.
[132] Ding‐Shinn Chen,et al. ADAR2-Mediated Editing of miR-214 and miR-122 Precursor and Antisense RNA Transcripts in Liver Cancers , 2013, PloS one.
[133] Yiannis A. Savva,et al. RNA editing regulates transposon-mediated heterochromatic gene silencing , 2013, Nature Communications.
[134] K. Nishikura,et al. Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[135] T. Billiar,et al. Adenosine Deaminase Acting on RNA 1 Limits RIG-I RNA Detection and Suppresses IFN Production Responding to Viral and Endogenous RNAs , 2014, The Journal of Immunology.
[136] Chris P. Ponting,et al. The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA , 2014, Cell reports.
[137] Jens Lagergren,et al. A-to-I editing of microRNAs in the mammalian brain increases during development , 2012, Genome research.
[138] A. Scadden,et al. Proteins that contain a functional Z-DNA-binding domain localize to cytoplasmic stress granules , 2013, Nucleic acids research.
[139] Joshua J C Rosenthal,et al. Control of human potassium channel inactivation by editing of a small mRNA hairpin , 2004, Nature Structural &Molecular Biology.
[140] K. Nishikura,et al. Editor meets silencer: crosstalk between RNA editing and RNA interference , 2006, Nature Reviews Molecular Cell Biology.
[141] Eli Eisenberg,et al. A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes , 2014, Genome research.
[142] G. Chawla,et al. ADAR mediates differential expression of polycistronic microRNAs , 2014, Nucleic acids research.
[143] Molly Megraw,et al. Frequency and fate of microRNA editing in human brain , 2008, Nucleic acids research.
[144] J. Wettengel,et al. Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans , 2014, Nucleic acids research.
[145] C. Sander,et al. Identification of microRNAs of the herpesvirus family , 2005, Nature Methods.