Structural and functional characterisation of two proteolytic fragments of the bacterial protein toxin, pneumolysin

[1]  S. Bhakdi,et al.  Membrane-penetrating Domain of Streptolysin O Identified by Cysteine Scanning Mutagenesis* , 1996, The Journal of Biological Chemistry.

[2]  J. R. de los Toyos,et al.  Functional analysis of pneumolysin by use of monoclonal antibodies , 1996, Infection and immunity.

[3]  H. Bayley,et al.  Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: prototypes of pore-forming bacterial cytolysins , 1996, Archives of Microbiology.

[4]  H. Saibil,et al.  Subunit organisation and symmetry of pore‐forming, oligomeric pneumolysin , 1995, FEBS letters.

[5]  S. Bhakdi,et al.  Kinetics of streptolysin O self-assembly. , 1995, European journal of biochemistry.

[6]  M. Nakamura,et al.  Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion. , 1995, Biochemistry.

[7]  P. Andrew,et al.  Modeling the bacterial protein toxin, pneumolysin, in its monomeric and oligomeric form. , 1994, The Journal of biological chemistry.

[8]  P. Andrew,et al.  A role in cell-binding for the C-terminus of pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae. , 1994, FEMS microbiology letters.

[9]  P. Andrew,et al.  Characterization of the solution properties and conformation of pneumolysin, the membrane-damaging toxin of Streptococcus pneumoniae. , 1993, The Biochemical journal.

[10]  S. Harding,et al.  The multicatalytic proteinase complex (proteasome): structure and conformational changes associated with changes in proteolytic activity. , 1993, The Biochemical journal.

[11]  Y. Korchev,et al.  Membrane damage: common mechanisms of induction and prevention. , 1992, FEMS microbiology immunology.

[12]  P. Sims,et al.  Isolation of a tryptic fragment from Clostridium perfringens theta-toxin that contains sites for membrane binding and self-aggregation. , 1991, The Journal of biological chemistry.

[13]  J. Alouf,et al.  Sourcebook of bacterial protein toxins , 1991 .

[14]  S. Ando,et al.  Effect of isolated C-terminal fragment of theta-toxin (perfringolysin O) on toxin assembly and membrane lysis. , 1990, European journal of biochemistry.

[15]  D. Briles,et al.  Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae , 1989, Infection and immunity.

[16]  P. Andrew,et al.  Expression of the pneumolysin gene in Escherichia coli: rapid purification and biological properties. , 1989, Biochimica et biophysica acta.

[17]  G. Boulnois,et al.  Molecular cloning, characterization, and complete nucleotide sequence of the gene for pneumolysin, the sulfhydryl-activated toxin of Streptococcus pneumoniae , 1987, Infection and immunity.

[18]  H. Kawasaki,et al.  Cold-labile hemolysin produced by limited proteolysis of theta-toxin from Clostridium perfringens. , 1986, Biochemistry.

[19]  J T Yang,et al.  Calculation of protein conformation from circular dichroism. , 1986, Methods in enzymology.

[20]  R Austrian,et al.  Pneumococcus: the first one hundred years. , 1981, Reviews of infectious diseases.

[21]  K. Kim,et al.  Alteration by cereolysin of the structure of cholesterol-containing membranes. , 1978, Biochimica et biophysica acta.

[22]  R. Pain,et al.  The determination of molecular weights of biological macromolecules by ultracentrifuge methods. , 1967, Progress in biophysics and molecular biology.

[23]  D. A. Yphantis.  EQUILIBRIUM ULTRACENTRIFUGATION OF DILUTE SOLUTIONS. , 1964, Biochemistry.