Cystamine metabolism and brain transport properties: clinical implications for neurodegenerative diseases
暂无分享,去创建一个
[1] P. Chan,et al. Effects of cysteamine on MPTP-induced dopaminergic neurodegeneration in mice , 2010, Brain Research.
[2] F. Cicchetti,et al. Cystamine prevents MPTP-induced toxicity in young adult mice via the up-regulation of the brain-derived neurotrophic factor , 2010, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[3] F. LaFerla,et al. Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood–brain barrier: An in situ cerebral perfusion study , 2009, Neurochemistry International.
[4] S. Szabó,et al. Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism. , 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[5] R. Ferrante,et al. Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease. , 2008, Biochimica et biophysica acta.
[6] J. Dominy,et al. Discovery and Characterization of a Second Mammalian Thiol Dioxygenase, Cysteamine Dioxygenase* , 2007, Journal of Biological Chemistry.
[7] R. de Kanter,et al. Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction , 2006, Expert opinion on drug metabolism & toxicology.
[8] B. Reusens,et al. Is taurine a functional nutrient? , 2006, Current opinion in clinical nutrition and metabolic care.
[9] M. Tremblay,et al. Neuroprotective effects of cystamine in aged parkinsonian mice , 2006, Neurobiology of Aging.
[10] T. Funatsu,et al. Suppression of thiol exchange reaction in the determination of reduced-form thiols by high-performance liquid chromatography with fluorescence detection after derivatization with fluorogenic benzofurazan reagent, 7-fluoro-2,1,3-benzoxadiazole-4-sulfonate and 4-aminosulfonyl-7-fluoro-2,1,3-benzoxadia , 2006, Biomedical chromatography : BMC.
[11] E. Hirsch,et al. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. , 2006, The Journal of clinical investigation.
[12] R. Dubinsky,et al. CYTE‐I‐HD: Phase I dose finding and tolerability study of cysteamine (Cystagon) in Huntington's disease , 2006, Movement disorders : official journal of the Movement Disorder Society.
[13] M. Hayden,et al. Treatment of YAC128 mice and their wild‐type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease , 2005, Journal of neurochemistry.
[14] Francesca Cicchetti,et al. Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6/2 mouse model of Huntington's disease , 2005, Journal of the Neurological Sciences.
[15] Arthur J. L. Cooper,et al. Mechanism for the inhibition of transglutaminase 2 by cystamine. , 2005, Biochemical pharmacology.
[16] C. Rock,et al. Coenzyme A: back in action. , 2005, Progress in lipid research.
[17] S. Hersch,et al. Cystamine increases l‐cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation , 2004, Journal of neurochemistry.
[18] M. Stipanuk,et al. Regulation of cysteine dioxygenase and gamma-glutamylcysteine synthetase is associated with hepatic cysteine level. , 2004, The Journal of nutritional biochemistry.
[19] J. Temsamani,et al. Evidence for an active transport of morphine‐6‐β‐d‐glucuronide but not P‐glycoprotein‐mediated at the blood–brain barrier , 2003, Journal of neurochemistry.
[20] S. Hersch,et al. Therapeutic Effects of Cystamine in a Murine Model of Huntington's Disease , 2002, The Journal of Neuroscience.
[21] Sawsan Youssef,et al. Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine , 2002, Nature Medicine.
[22] Christophe Rousselle,et al. Development of an In Situ Mouse Brain Perfusion Model and its Application to mdr1a P-Glycoprotein-Deficient Mice , 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[23] P. Blanchet,et al. Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: effects on basal ganglia GABAA/benzodiazepine receptor complex and GABA content , 1999, Neurochemistry International.
[24] S. Oja,et al. Taurine as osmoregulator and neuromodulator in the brain , 1996, Metabolic Brain Disease.
[25] J. Bourre,et al. Taurine transport at the blood-brain barrier: an in vivo brain perfusion study , 1995, Brain Research.
[26] H. Green. Human genetic diseases due to codon reiteration: Relationship to an evolutionary mechanism , 1993, Cell.
[27] C. L. Ursini,et al. Enzymatic synthesis of S-aminoethyl-L-cysteine from pantetheine. , 1992, Biochimica et biophysica acta.
[28] L. A. Wade,et al. Cysteine and Cystine Transport at the Blood‐Brain Barrier , 1982, Journal of neurochemistry.
[29] A. Lajtha,et al. INHIBITION PATTERN BY ANALOGS INDICATES THE PRESENCE OF TEN OR MORE TRANSPORT SYSTEMS FOR AMINO ACIDS IN BRAIN CELLS , 1979, Journal of neurochemistry.
[30] R. Katzman.,et al. SYNTHETIC AMINO ACIDS AND THE NATURE OF l‐DOPA TRANSPORT AT THE BLOOD‐BRAIN BARRIER , 1975, Journal of neurochemistry.
[31] B. Sörbo,et al. Characteristics of the cysteinesulfinate-forming enzyme system in rat liver. , 1966, Biochimica et biophysica acta.
[32] Beaumariage Ml,et al. [RADIOPROTECTIVE ACTION OF CYSTEAMINE AND CYSTAMINE IN MICE AS A FUNCTION OF THE PERIOD OF TIME BETWEEN INJECTION OF THE PROTECTOR AND THE START OF X-RAY IRRADIATION]. , 1965 .
[33] R. Scandurra,et al. THE ENZYMATIC OXIDATION OF CYSTEAMINE TO HYPOTAURINE IN THE PRESENCE OF SULFIDE. , 1963, The Journal of biological chemistry.
[34] Bruce A Barshop,et al. Twice-daily cysteamine bitartrate therapy for children with cystinosis. , 2010, The Journal of pediatrics.
[35] J. Dominy,et al. Cysteamine dioxygenase: evidence for the physiological conversion of cysteamine to hypotaurine in rat and mouse tissues. , 2006, Advances in experimental medicine and biology.
[36] R. Dawson,et al. Building Biosynthetic Schools: Reviewing Compartmentation of CNS Taurine Synthesis , 2004, Neurochemical Research.
[37] R J Huxtable,et al. Physiological actions of taurine. , 1992, Physiological reviews.
[38] C. Saller,et al. gamma-Aminobutyric acid, glutamate, glycine and taurine analysis using reversed-phase high-performance liquid chromatography and ultraviolet detection of dansyl chloride derivatives. , 1989, Journal of chromatography.
[39] R. Schwarcz,et al. Anti-excitotoxic actions of taurine in the rat hippocampus studied in vivo and in vitro. , 1986, Advances in experimental medicine and biology.
[40] H. Pasantes‐Morales,et al. The role of taurine in nervous tissue: its effects on ionic fluxes. , 1981, Advances in experimental medicine and biology.
[41] K. Kuriyama,et al. A modulating role of taurine on release of acetylcholine and norepinephrine from neuronal tissues. , 1978, Japanese journal of pharmacology.
[42] W H Oldendorf,et al. Amino acid assignment to one of three blood-brain barrier amino acid carriers. , 1976, The American journal of physiology.