Robustness of virus removal by protein A chromatography is independent of media lifetime.

[1]  R. Hedges,et al.  Properties of R plasmid R772 and the corresponding pilus-specific phage PR772. , 1979, Journal of general microbiology.

[2]  P. Bekker,et al.  Pilus-specific, lipid-containing bacteriophages PR4 and PR772: comparison of physical characteristics of genomes. , 1979, The Journal of general virology.

[3]  G. V. D. Plaats,et al.  A study on the sizing process of an instrument based on the electrical sensing zone principle. Part 2. The influence of particle porosity , 1983 .

[4]  Howard G. Barth,et al.  Modern methods of particle size analysis , 1984 .

[5]  F. Regnier,et al.  Effects of large sample loads on column lifetime in preparative-scale liquid chromatography. , 1987, Journal of chromatography.

[6]  P. Füglistaller,et al.  Comparison of immunoglobulin binding capacities and ligand leakage using eight different protein A affinity chromatography matrices. , 1989, Journal of immunological methods.

[7]  J. Arrand,et al.  A cloned AluI-equivalent repetitive sequence that detects transfected hamster DNA. , 1990, Gene.

[8]  E. Boschetti,et al.  Composite affinity sorbents and their cleaning in place. , 1990, Journal of chromatography.

[9]  V. Marks,et al.  Assessment of the suitability of commercially available SpA affinity solid phases for the purification of murine monoclonal antibodies at process scale. , 1993, Journal of immunological methods.

[10]  G. Hale,et al.  Repeated cleaning of protein A affinity column with sodium hydroxide. , 1994, Journal of immunological methods.

[11]  F. B. Anspach,et al.  Removal of endotoxins by affinity sorbents. , 1995, Journal of chromatography. A.

[12]  E. Bill,et al.  Optimization of protein G chromatography for bio pharmaceutical monoclonal antibodies , 1995, Journal of molecular recognition : JMR.

[13]  U. Rinas,et al.  Purification of recombinant human basic fibroblast growth factor: stability of selective sorbents under cleaning in place conditions. , 1995, Journal of chromatography. A.

[14]  K. Peden,et al.  Adaptation of the fluorogenic 5'-nuclease chemistry to a PCR-based reverse transcriptase assay. , 1998, BioTechniques.

[15]  H. Mori,et al.  Effect of particle shape on the particle size distribution measured with commercial equipment , 1998 .

[16]  Y. Xu,et al.  A real time quantitative PCR-based method for the detection and quantification of simian virus 40. , 1999, Biologicals : journal of the International Association of Biological Standardization.

[17]  Y. Xu,et al.  Real time quantitative PCR as a method to evaluate simian virus 40 removal during pharmaceutical protein purification. , 1999, Biologicals : journal of the International Association of Biological Standardization.

[18]  P. Levison,et al.  Influence of column design on process-scale ion-exchange chromatography. , 1999, Journal of chromatography. A.

[19]  M Vanderlaan,et al.  Performance comparison of Protein A affinity‐chromatography sorbents for purifying recombinant monoclonal antibodies , 1999, Biotechnology and applied biochemistry.

[20]  C. Fautz,et al.  Real-time quantitative PCR for retrovirus-like particle quantification in CHO cell culture. , 2000, Biologicals : journal of the International Association of Biological Standardization.

[21]  M Vanderlaan,et al.  Industrial Purification of Pharmaceutical Antibodies: Development, Operation, and Validation of Chromatography Processes , 2001, Biotechnology & genetic engineering reviews.

[22]  V. Préat,et al.  Comparison of particle sizing techniques in the case of inhalation dry powders. , 2001, Journal of pharmaceutical sciences.

[23]  Patrick G. Swann,et al.  Use of a Quantitative Product‐Enhanced Reverse Transcriptase Assay to Monitor Retrovirus Levels in mAb Cell‐Culture and Downstream Processing , 2001, Biotechnology progress.

[24]  Patrick G. Swann,et al.  Evaluation of a quantitative product-enhanced reverse transcriptase assay to monitor retrovirus in mAb cell-culture. , 2002, Biologicals : journal of the International Association of Biological Standardization.

[25]  Kurt Brorson,et al.  Impact of cell culture process changes on endogenous retrovirus expression. , 2002, Biotechnology and bioengineering.

[26]  J. Vennari,et al.  Detection of minute virus of mice using real time quantitative PCR in assessment of virus clearance during the purification of Mammalian cell substrate derived biotherapeutics. , 2002, Biologicals : journal of the International Association of Biological Standardization.

[27]  R. Xu,et al.  Comparison of sizing small particles using different technologies , 2003 .

[28]  K. Brorson,et al.  Identification of protein A media performance attributes that can be monitored as surrogates for retrovirus clearance during extended re-use. , 2003, Journal of chromatography. A.

[29]  Janice W Chen,et al.  Application of multivirus spike approach for viral clearance evaluation , 2003, Biotechnology and bioengineering.

[30]  Alois Jungbauer,et al.  Comparison of protein A affinity sorbents. , 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[31]  Liming Shi,et al.  Real time quantitative PCR as a method to evaluate xenotropic murine leukemia virus removal during pharmaceutical protein purification , 2004, Biotechnology and bioengineering.

[32]  Hazel Aranha,et al.  Characterization of Coliphage PR772 and Evaluation of Its Use for Virus Filter Performance Testing , 2004, Applied and Environmental Microbiology.

[33]  A. Staby,et al.  Comparison of chromatographic ion-exchange resins IV. Strong and weak cation-exchange resins and heparin resins. , 2005, Journal of chromatography. A.

[34]  Kurt Brorson,et al.  Impact of multiple re-use of anion-exchange chromatography media on virus removal. , 2005, Journal of chromatography. A.

[35]  F. Steindl,et al.  Comparison of protein A affinity sorbents III. Life time study. , 2006, Journal of chromatography. A.

[36]  B. Kelley,et al.  Viral clearance studies on new and used chromatography resins: critical review of a large dataset. , 2008, Biologicals : journal of the International Association of Biological Standardization.