Rhodiola crenulata extract suppresses hepatic gluconeogenesis via activation of the AMPK pathway.

[1]  T. Efferth,et al.  Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data. , 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[2]  Hang-Ching Lin,et al.  The Inhibitory Effect of Ginsenoside Rg1 on Glucose and Lipid Production in Human HepG2 Cells , 2013 .

[3]  H. Ngan,et al.  Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade , 2013, BMC Cancer.

[4]  Chih-Yang Huang,et al.  Rhodiola crenulata and Its Bioactive Components, Salidroside and Tyrosol, Reverse the Hypoxia-Induced Reduction of Plasma-Membrane-Associated Na,K-ATPase Expression via Inhibition of ROS-AMPK-PKCξ Pathway , 2013, Evidence-based complementary and alternative medicine : eCAM.

[5]  L. Goya,et al.  Cocoa flavonoids improve insulin signalling and modulate glucose production via AKT and AMPK in HepG2 cells. , 2013, Molecular nutrition & food research.

[6]  Min-Hui Li,et al.  Rhodiola crenulata Extract Alleviates Hypoxic Pulmonary Edema in Rats , 2013, Evidence-based complementary and alternative medicine : eCAM.

[7]  Thomas Efferth,et al.  Synergy and Antagonism of Active Constituents of ADAPT-232 on Transcriptional Level of Metabolic Regulation of Isolated Neuroglial Cells , 2013, Front. Neurosci..

[8]  Yan Peng,et al.  Isolation, identification and antioxidative capacity of water-soluble phenylpropanoid compounds from Rhodiola crenulata. , 2012, Food chemistry.

[9]  Yifan Yang,et al.  Rhodiola crenulata root ameliorates derangements of glucose and lipid metabolism in a rat model of the metabolic syndrome and type 2 diabetes. , 2012, Journal of ethnopharmacology.

[10]  S. Bulik,et al.  Quantifying the Contribution of the Liver to Glucose Homeostasis: A Detailed Kinetic Model of Human Hepatic Glucose Metabolism , 2012, PLoS Comput. Biol..

[11]  R. Shaw,et al.  The AMPK signalling pathway coordinates cell growth, autophagy and metabolism , 2011, Nature Cell Biology.

[12]  Hang-Ching Lin,et al.  Pachymic acid stimulates glucose uptake through enhanced GLUT4 expression and translocation. , 2010, European journal of pharmacology.

[13]  R. Watanabe,et al.  Pharmacogenetics of Anti-Diabetes Drugs , 2010, Pharmaceuticals.

[14]  J. Sarris,et al.  Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. , 2010, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[15]  Young Woo Kim,et al.  AMPK-mediated GSK3beta inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress. , 2010, Biochemical pharmacology.

[16]  J. Mitchell,et al.  The PPARβ/δAgonist GW0742 Relaxes Pulmonary Vessels and Limits Right Heart Hypertrophy in Rats with Hypoxia-Induced Pulmonary Hypertension , 2010, PloS one.

[17]  Mengwei Zang,et al.  AMPK exerts dual regulatory effects on the PI3K pathway , 2010, Journal of molecular signaling.

[18]  Shijie Li,et al.  Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis , 2010, Proceedings of the National Academy of Sciences.

[19]  Gaochao Zhou,et al.  AMPK: an emerging drug target for diabetes and the metabolic syndrome. , 2009, Cell metabolism.

[20]  B. Viollet,et al.  AMP‐activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives , 2009, Acta physiologica.

[21]  Y. Uchijima,et al.  AMP-activated Protein Kinase Activation Increases Phosphorylation of Glycogen Synthase Kinase 3β and Thereby Reduces cAMP-responsive Element Transcriptional Activity and Phosphoenolpyruvate Carboxykinase C Gene Expression in the Liver* , 2008, Journal of Biological Chemistry.

[22]  Le Zhang,et al.  Salidroside stimulated glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase. , 2008, European journal of pharmacology.

[23]  Hao Zhang,et al.  Identification and comparative determination of rhodionin in traditional tibetan medicinal plants of fourteen Rhodiola species by high-performance liquid chromatography-photodiode array detection and electrospray ionization-mass spectrometry. , 2008, Chemical & pharmaceutical bulletin.

[24]  R. Tulsawani,et al.  A dose dependent adaptogenic and safety evaluation of Rhodiola imbricata Edgew, a high altitude rhizome. , 2008, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[25]  Hui-yu Liu,et al.  Epigallocatechin-3-gallate (EGCG), A Green Tea Polyphenol, Suppresses Hepatic Gluconeogenesis through 5′-AMP-activated Protein Kinase* , 2007, Journal of Biological Chemistry.

[26]  A. Panossian,et al.  Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression , 2007, Nordic journal of psychiatry.

[27]  N. de Kimpe,et al.  Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. , 2004, Journal of ethnopharmacology.

[28]  Wei-Hua Chen,et al.  [Effects of salidroside on carbohydrate metabolism and differentiation of 3T3-L1 adipocytes]. , 2004, Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.

[29]  J. Ling.  Rhodiola crenulata with life style to 27 treatment for 2 type diabetes sufferers evaluation , 2007 .