Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces mRNA translation initiation and nutrient sensing in fetal liver and skeletal muscle
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J. Friedman | P. Rozance | R. Wilkening | W. Hay | T. Regnault | L. Brown | S. R. Thorn | M. Roper | J. Keng | Jane A. Keng
[1] J. Auwerx,et al. Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation. , 2008, Cell metabolism.
[2] J. Tong,et al. AMP‐activated protein kinase signalling pathways are down regulated and skeletal muscle development impaired in fetuses of obese, over‐nourished sheep , 2008, The Journal of physiology.
[3] B. Turk,et al. AMPK phosphorylation of raptor mediates a metabolic checkpoint. , 2008, Molecular cell.
[4] M. Sahin,et al. Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis. , 2008, Molecular cell.
[5] Nicholas E. Bruns,et al. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy , 2008, Proceedings of the National Academy of Sciences.
[6] J. Friedman,et al. Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep. , 2008, American journal of physiology. Endocrinology and metabolism.
[7] P. Houghton,et al. mTORC1 Signaling Can Regulate Growth Factor Activation of p44/42 Mitogen-activated Protein Kinases through Protein Phosphatase 2A* , 2008, Journal of Biological Chemistry.
[8] P. Rozance,et al. Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction. , 2007, American journal of physiology. Endocrinology and metabolism.
[9] V. Mootha,et al. mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex , 2007, Nature.
[10] W. Hay,et al. Sensitivity to metabolic signals in late-gestation growth-restricted fetuses from rapidly growing adolescent sheep. , 2007, American journal of physiology. Endocrinology and metabolism.
[11] I. McMillen,et al. Restriction of placental growth in sheep impairs insulin secretion but not sensitivity before birth , 2007, The Journal of physiology.
[12] D. Hardie,et al. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy , 2007, Nature Reviews Molecular Cell Biology.
[13] R. Wilkening,et al. Development and mechanisms of fetal hypoxia in severe fetal growth restriction. , 2007, Placenta.
[14] P. Walter,et al. Signal integration in the endoplasmic reticulum unfolded protein response , 2007, Nature Reviews Molecular Cell Biology.
[15] S. Ozanne,et al. Experimental IUGR and later diabetes , 2007, Journal of internal medicine.
[16] P. Puigserver,et al. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α , 2007, The EMBO journal.
[17] P. Vuguin. Animal Models for Small for Gestational Age and Fetal Programing of Adult Disease , 2007, Hormone Research in Paediatrics.
[18] Jeffrey S. Robinson,et al. Placental restriction of fetal growth increases insulin action, growth, and adiposity in the young lamb. , 2007, Endocrinology.
[19] Jeffrey S. Robinson,et al. Placental restriction of fetal growth reduces size at birth and alters postnatal growth, feeding activity, and adiposity in the young lamb. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.
[20] C. Tsigos,et al. Stress, the Endoplasmic Reticulum, and Insulin Resistance , 2006, Annals of the New York Academy of Sciences.
[21] Brian A. Hemmings,et al. Only Akt1 Is Required for Proliferation, while Akt2 Promotes Cell Cycle Exit through p21 Binding , 2006, Molecular and Cellular Biology.
[22] B. Kahn,et al. Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. , 2006, The Journal of clinical investigation.
[23] J. Zierath,et al. AMP-activated protein kinase signaling in metabolic regulation. , 2006, The Journal of clinical investigation.
[24] L. Cantley,et al. Ras, PI(3)K and mTOR signalling controls tumour cell growth , 2006, Nature.
[25] W. Hay. Recent observations on the regulation of fetal metabolism by glucose , 2006, The Journal of physiology.
[26] P. Rozance,et al. Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction. , 2006, Endocrinology.
[27] H. Vestergaard,et al. IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients. , 2006, Diabetes.
[28] M. Cornier,et al. Nutritional upregulation of p85α expression is an early molecular manifestation of insulin resistance , 2006, Diabetologia.
[29] M. Hall,et al. TOR Signaling in Growth and Metabolism , 2006, Cell.
[30] C. Kahn,et al. Critical nodes in signalling pathways: insights into insulin action , 2006, Nature Reviews Molecular Cell Biology.
[31] C. Kahn,et al. Increased P85α Is a Potent Negative Regulator of Skeletal Muscle Insulin Signaling and Induces in Vivo Insulin Resistance Associated with Growth Hormone Excess* , 2005, Journal of Biological Chemistry.
[32] M. Montminy,et al. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism , 2005, Nature.
[33] B. V. van Bon,et al. Programming of glucose-insulin metabolism in adult sheep after maternal undernutrition. , 2005, American journal of physiology. Regulatory, integrative and comparative physiology.
[34] J. Ofrecio,et al. Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle. , 2005, Diabetes.
[35] P. Czernichow,et al. Dynamic change in adiposity from fetal to postnatal life is involved in the metabolic syndrome associated with reduced fetal growth , 2005, Diabetologia.
[36] Jeffrey S. Robinson,et al. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. , 2005, Physiological reviews.
[37] Wilhelm Haas,et al. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1 , 2005, Nature.
[38] A. Vaag,et al. Low birthweight is associated with specific changes in muscle insulin-signalling protein expression , 2005, Diabetologia.
[39] R. Wilkening,et al. Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction. , 2004, American journal of physiology. Endocrinology and metabolism.
[40] Mei J. Zhu,et al. Effect of Maternal Nutrient Restriction in Sheep on the Development of Fetal Skeletal Muscle1 , 2004, Biology of reproduction.
[41] N. Barzilai,et al. Hepatic insulin resistance precedes the development of diabetes in a model of intrauterine growth retardation. , 2004, Diabetes.
[42] N. Sonenberg,et al. Upstream and downstream of mTOR. , 2004, Genes & development.
[43] B. Hemmings,et al. Physiological functions of protein kinase B/Akt. , 2004, Biochemical Society transactions.
[44] R. Wilkening,et al. The relationship between transplacental O2 diffusion and placental expression of PlGF, VEGF and their receptors in a placental insufficiency model of fetal growth restriction , 2003, The Journal of physiology.
[45] Bruce M. Spiegelman,et al. Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction , 2003, Nature.
[46] A. Musarò,et al. Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice , 2002, The Journal of cell biology.
[47] J. Testa,et al. Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts. , 2002, Endocrinology.
[48] D. Barker,et al. The thrifty phenotype hypothesis. , 2001, British medical bulletin.
[49] P. Rotwein,et al. Insulin-like Growth Factor-mediated Muscle Differentiation , 2001, The Journal of Biological Chemistry.
[50] Guillaume Adelmant,et al. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 , 2001, Nature.
[51] Marc Montminy,et al. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 , 2001, Nature.
[52] B. Hemmings,et al. Protein Kinase B β/Akt2 Plays a Specific Role in Muscle Differentiation* , 2001, The Journal of Biological Chemistry.
[53] D. Keisler,et al. Leptin regulates pulsatile luteinizing hormone and growth hormone secretion in the sheep. , 2000, Endocrinology.
[54] M. R. Calera,et al. Induction of Akt-2 correlates with differentiation in Sol8 muscle cells. , 1998, Biochemical and biophysical research communications.
[55] G. Bell,et al. Altered Hepatic Gene Expression of Enzymes Involved in Energy Metabolism in the Growth-Retarded Fetal Rat , 1996, Pediatric Research.
[56] J. C. Ross,et al. Placental transport and fetal utilization of leucine in a model of fetal growth retardation. , 1996, The American journal of physiology.
[57] R. Wilkening,et al. Placental glucose transport in heat-induced fetal growth retardation. , 1992, The American journal of physiology.
[58] M. Divon,et al. Intrauterine Growth Retardation: Definition, Classification, and Etiology , 1992, Clinical obstetrics and gynecology.
[59] G. Meschia,et al. Transplacental diffusion of ethanol under steady state conditions. , 1980, Journal of developmental physiology.
[60] W. Hay,et al. Utilization of substrates by the ovine placenta in vivo. , 1980, Federation proceedings.
[61] D. Mellor,et al. Daily changes in the curved crown-rump length of individual sheep fetuses during the last 60 days of pregnancy and effects of different levels of maternal nutrition. , 1979, Quarterly journal of experimental physiology and cognate medical sciences.
[62] G. Meschia,et al. Principal substrates of fetal metabolism. , 1978, Physiological reviews.
[63] M. D. Jones,et al. Placental production and foetal utilisation of lactate and pyruvate , 1975, Nature.
[64] J. Friedman,et al. Insulin is required for amino acid stimulation of dual pathways for translational control in skeletal muscle in the late-gestation ovine fetus. , 2009, American journal of physiology. Endocrinology and metabolism.
[65] W. Hay,et al. Leucine metabolism in chronically hypoglycemic hypoinsulinemic growth-restricted fetal sheep. , 1997, The American journal of physiology.
[66] W. Oh,et al. Persistent glucose production and greater peripheral sensitivity to insulin in the neonate vs. the adult. , 1997, The American journal of physiology.
[67] H. S. Brar,et al. Classification of intrauterine growth retardation , 1988 .