Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.
暂无分享,去创建一个
J. Seidman | J. Balschi | C. Seidman | H. Wakimoto | J. Ingwall | L. Goodyear | R. Tian | N. Musi | M. Hirshman | H. Morita | M. Shen | M. Arad | Huamei He | I. Luptak | Jie Yan
[1] B. Kemp,et al. Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation. , 2007, American journal of physiology. Endocrinology and metabolism.
[2] N. Fujii,et al. Muscle-specific overexpression of wild type and R225Q mutant AMP-activated protein kinase gamma3-subunit differentially regulates glycogen accumulation. , 2006, American journal of physiology. Endocrinology and metabolism.
[3] J. Schneider,et al. Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome. , 2006, American journal of physiology. Heart and circulatory physiology.
[4] Sofia Martinsson,et al. Opposite Transcriptional Regulation in Skeletal Muscle of AMP-activated Protein Kinase γ3 R225Q Transgenic Versus Knock-out Mice* , 2006, Journal of Biological Chemistry.
[5] Ferhaan Ahmad,et al. Increased &agr;2 Subunit–Associated AMPK Activity and PRKAG2 Cardiomyopathy , 2005, Circulation.
[6] J. Balschi,et al. Decreased Contractile and Metabolic Reserve in Peroxisome Proliferator–Activated Receptor-&agr;–Null Hearts Can Be Rescued by Increasing Glucose Transport and Utilization , 2005, Circulation.
[7] J. Seidman,et al. N488I Mutation of the γ2-Subunit Results in Bidirectional Changes in AMP-Activated Protein Kinase Activity , 2005 .
[8] J. Seidman,et al. Glycogen storage diseases presenting as hypertrophic cardiomyopathy. , 2005, The New England journal of medicine.
[9] G. Taffet,et al. Transgenic Mouse Model of Ventricular Preexcitation and Atrioventricular Reentrant Tachycardia Induced by an AMP-Activated Protein Kinase Loss-of-Function Mutation Responsible for Wolff-Parkinson-White Syndrome , 2005, Circulation.
[10] B. Viollet,et al. The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading. , 2004, Diabetes.
[11] B. Lorell,et al. Mechanisms for Increased Glycolysis in the Hypertrophied Rat Heart , 2004, Hypertension.
[12] G. Hjälm,et al. The 5′-AMP-activated Protein Kinase γ3 Isoform Has a Key Role in Carbohydrate and Lipid Metabolism in Glycolytic Skeletal Muscle* , 2004, Journal of Biological Chemistry.
[13] M. Birnbaum,et al. AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. , 2004, The Journal of clinical investigation.
[14] J. Hedegaard,et al. UDP‐Glucose pyrophosphorylase is upregulated in carriers of the porcine RN− mutation in the AMP‐activated protein kinase , 2004, Proteomics.
[15] N. Fujii,et al. Glucose Metabolism and Energy Homeostasis in Mouse Hearts Overexpressing Dominant Negative α2 Subunit of AMP-activated Protein Kinase* , 2003, Journal of Biological Chemistry.
[16] Ferhaan Ahmad,et al. Transgenic Mice Overexpressing Mutant PRKAG2 Define the Cause of Wolff-Parkinson-White Syndrome in Glycogen Storage Cardiomyopathy , 2003, Circulation.
[17] Y. Hellsten,et al. Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle. , 2003, American journal of physiology. Endocrinology and metabolism.
[18] B. Hansen,et al. AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle. , 2002, American journal of physiology. Endocrinology and metabolism.
[19] Mohit M. Jain,et al. Cardiac-Specific Overexpression of GLUT1 Prevents the Development of Heart Failure Attributable to Pressure Overload in Mice , 2002, Circulation.
[20] J. Seidman,et al. Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy. , 2002, The Journal of clinical investigation.
[21] L. Fananapazir,et al. Identification of a gene responsible for familial Wolff-Parkinson-White syndrome. , 2001, The New England journal of medicine.
[22] L. Goodyear,et al. Increased Adenosine Monophosphate–Activated Protein Kinase Activity in Rat Hearts With Pressure-Overload Hypertrophy , 2001, Circulation.
[23] H. Watkins,et al. Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis. , 2001, Human molecular genetics.
[24] W. Derave,et al. Glycogen synthase localization and activity in rat skeletal muscle is strongly dependent on glycogen content , 2001, The Journal of physiology.
[25] D. Carling,et al. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia , 2000, Current Biology.
[26] P. Roach,et al. Glycogen synthase sensitivity to insulin and glucose-6-phosphate is mediated by both NH2- and COOH-terminal phosphorylation sites. , 2000, Diabetes.
[27] W. Winder,et al. Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle. , 2000, Journal of applied physiology.
[28] C. Rogel-Gaillard,et al. A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle. , 2000, Science.
[29] N. Fujii,et al. Activation of AMP-Activated Protein Kinase as a Unifying Coupling Mechanism , 2000 .
[30] B. Lowell,et al. Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. , 1999, The Journal of clinical investigation.
[31] W. Winder,et al. Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. , 1999, Journal of applied physiology.
[32] M. Rider,et al. Mechanisms of control of heart glycolysis. , 1998, European journal of biochemistry.
[33] J. Ingwall,et al. Impaired cardiac energetics in mice lacking muscle-specific isoenzymes of creatine kinase. , 1998, Circulation research.
[34] S. E. Brodie. New York, New York, USA , 1996 .
[35] G. Lopaschuk,et al. High Rates of Fatty Acid Oxidation during Reperfusion of Ischemic Hearts Are Associated with a Decrease in Malonyl-CoA Levels Due to an Increase in 5′-AMP-activated Protein Kinase Inhibition of Acetyl-CoA Carboxylase (*) , 1995, The Journal of Biological Chemistry.
[36] R. Balaban,et al. Nonglucose substrates increase glycogen synthesis in vivo in dog heart. , 1994, The American journal of physiology.
[37] D. Hardie,et al. Role of the AMP-activated protein kinase in the cellular stress response , 1994, Current Biology.
[38] J. Robbins,et al. Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice. , 1991, The Journal of biological chemistry.
[39] J. Gulick,et al. Isolation and characterization of the mouse cardiac myosin heavy chain genes. , 1991, The Journal of biological chemistry.
[40] G. Lyons,et al. Developmental regulation of myosin gene expression in mouse cardiac muscle , 1990, The Journal of cell biology.
[41] A. Sherry,et al. Analysis of tricarboxylic acid cycle of the heart using 13C isotope isomers. , 1990, The American journal of physiology.
[42] A. Sherry,et al. Evaluation of carbon flux and substrate selection through alternate pathways involving the citric acid cycle of the heart by 13C NMR spectroscopy. , 1988, The Journal of biological chemistry.
[43] D. E. Atkinson,et al. Uridine diphosphate glucose synthase from calf liver: determinants of enzyme activity in vitro. , 1975, Biochemistry.
[44] J. Passonneau,et al. A comparison of three methods of glycogen measurement in tissues. , 1974, Analytical biochemistry.
[45] J. Williamson. GLYCOLYTIC CONTROL MECHANISMS. I. INHIBITION OF GLYCOLYSIS BY ACETATE AND PYRUVATE IN THE ISOLATED, PERFUSED RAT HEART. , 1965, The Journal of biological chemistry.
[46] Oliver H. Lowry,et al. Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.
[47] J. Seidman,et al. N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity. , 2005, Circulation research.
[48] O. Pedersen,et al. Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner. , 2001, Diabetes.
[49] B. Kemp,et al. Dealing with energy demand: the AMP-activated protein kinase. , 1999, Trends in biochemical sciences.
[50] D. Hardie,et al. The AMP-activated protein kinase--fuel gauge of the mammalian cell? , 1997, European journal of biochemistry.
[51] O. H. Lowry,et al. A Collection of Metabolite Assays , 1993 .
[52] J. A. Thomas,et al. A rapid filter paper assay for UDPglucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose. , 1968, Analytical biochemistry.