Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals

[1]  S. Phan,et al.  The role of strain variation in murine bleomycin-induced pulmonary fibrosis. , 2015, The American review of respiratory disease.

[2]  E. Bancalari,et al.  Conditional overexpression of connective tissue growth factor disrupts postnatal lung development. , 2010, American journal of respiratory cell and molecular biology.

[3]  B. Perbal,et al.  Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes , 2009, Hepatology.

[4]  N. Alenina,et al.  Connective Tissue Growth Factor Overexpression in Cardiomyocytes Promotes Cardiac Hypertrophy and Protection against Pressure Overload , 2009, PloS one.

[5]  L. Lau,et al.  Functions and mechanisms of action of CCN matricellular proteins. , 2009, The international journal of biochemistry & cell biology.

[6]  D. Brigstock.  Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo , 2009, Journal of Cell Communication and Signaling.

[7]  J. Abreu,et al.  Ccn2/Ctgf Overexpression Induced by Cigarette Smoke during Cutaneous Wound Healing is Strain Dependent , 2009, Toxicologic pathology.

[8]  S. Parapuram,et al.  Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease? , 2009, Journal of Cell Communication and Signaling.

[9]  H. Yokoi,et al.  Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy in mice. , 2008, Kidney international.

[10]  Andrew Leask,et al.  All in the CCN family: essential matricellular signaling modulators emerge from the bunker , 2006, Journal of Cell Science.

[11]  M. Kolb,et al.  Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs. , 2004, American journal of respiratory cell and molecular biology.

[12]  F. Lammert,et al.  Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15. , 2002, Gastroenterology.

[13]  D. Abraham,et al.  Connective tissue growth factor: A new and important player in the pathogenesis of fibrosis , 2002, Current rheumatology reports.

[14]  M. Takigawa,et al.  Role and interaction of connective tissue growth factor with transforming growth factor‐β in persistent fibrosis: A mouse fibrosis model , 1999, Journal of cellular physiology.

[15]  D. Brigstock,et al.  Structural and functional properties of CCN proteins. , 2005, Vitamins and hormones.