Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Alberto Piazza | William Matthai | Flora Peyvandi | Changchun Xie | Carlo Berzuini | Vincent Mooser | Kari Stefansson | Isaac Subirana | Olle Melander | Leena Peltonen | Joan Sala | Nilesh J Samani | Wolfgang Lieb | Andreas Ziegler | Willem Ouwehand | Christopher J O'Donnell | David M Nathan | Gudmar Thorleifsson | Panos Deloukas | Sekar Kathiresan | Muredach P Reilly | Jeanette Erdmann | Heribert Schunkert | David Altshuler | Klaus Stark | Michael Preuss | Veikko Salomaa | Stefan Schreiber | Christian Hengstenberg | Diego Ardissino | Roberto Elosua | Jaume Marrugat | Mark J Daly | Inke R König | Giorgio Casari | Klaus Berger | Steven A McCarroll | Michele Galli | Shaun Purcell | Noel Burtt | Calum A MacRae | Kiran Musunuru | John A Spertus | Unnur Thorsteinsdottir | Ron Waksman | Joel N Hirschhorn | Marco Tubaro | Benjamin J. Wright | Luisa Bernardinelli | Stefano Duga | Monika Stoll | Thomas Scheffold | Marta Spreafico | P. Deloukas | S. Gabriel | M. Daly | U. Thorsteinsdóttir | L. Peltonen | K. Stefánsson | H. Hakonarson | S. Mccarroll | D. Altshuler | Mingyao Li | V. Salomaa | J. Hirschhorn | I. König | A. Ziegler | A. Piazza | W. Ouwehand | N. Samani | S. Ball | A. Balmforth | A. Hall | P. Braund | J. Thompson | J. Korn | Melissa Parkin | S. Purcell | J. Nemesh | L. Bernardinelli | J. Spertus | G. Thorleifsson | M. Reilly | D. Rader | D. Girelli | O. Olivieri | N. Martinelli | J. Erdmann | C. Hengstenberg | H. Wichmann | W. Lieb | F. Cambien | M. Fischer | H. Schunkert | D. Siscovick | A. Großhennig | P. Linsel-Nitschke | B. Wright | Michael H. Preuss | K. Stark | B. Voight | N. Burtt | S. Kathiresan | O. Melander | C. Guiducci | Lauren Gianniny | Aarti Surti | D. Ardissino | A. Havulinna | G. Berglund | J. Meigs | H. Hólm | V. Mooser | R. Wilensky | C. O’Donnell | R. Do | K. Berger | Y. Friedlander | S. Schwartz | M. Burnett | S. Epstein | D. Mirel | K. Kent | A. Pichard | L. Satler | Sonia S Anand | J. Marrugat | K. Musunuru | J. Engert | D. Nathan | D. Waterworth | G. Lucas | I. Subirana | F. Bernardi | C. Patterson | P. Mannucci | C. Macrae | J. Sala | R. Waksman | M. Tubaro | S. Duga | G. Casari | C. Xie | P. Merlini | A. Qasim | N. Marziliano | Michaela Scholz | M. Stoll | J. Devaney | F. Peyvandi | J. Lindsay | R. Asselta | C. Berzuini | R. Corrocher | R. Fetiveau | C. Knouff | P. McKeown | T. Morgan | M. Galli | Domenico Girelli | Oliviero Olivieri | Nicola Martinelli | Daniel J Rader | Ron Do | Benjamin F Voight | David S Siscovick | Roberto Corrocher | David Siscovick | Stacey B Gabriel | Anthony J Balmforth | Stephen G Ball | Stephen M Schwartz | Candace Guiducci | Aarti Surti | Aki S Havulinna | M. Ferrario | Francois Cambien | Andreas Huge | H-Erich Wichmann | James B Meigs | Dawn M Waterworth | James Nemesh | Mingyao Li | James C Engert | Alistair S Hall | Goran Berglund | Francesco Bernardi | Hilma Hólm | Max C Walker | Augusto D Pichard | Kenneth M Kent | F. Ribichini | Peter S Braund | W. Matthai | T. Scheffold | Sonia Anand | Rosanna Asselta | Nicola Marziliano | John R Thompson | M. Rossi | Raffaela Fetiveau | Lauren Gianniny | Yechiel Friedlander | Stephen E Epstein | Christopher W Knouff | Joseph M Lindsay | Robert Wilensky | Hakon H Hakonarson | Benjamin J Wright | P. Zonzin | Michael H Preuss | Atif Qasim | Chris C Patterson | Gordon Williams | Melissa Parkin | Pier M Mannucci | Anika Grosshennig | Thomas Morgan | Pascal P McKeown | Pier Angelica Merlini | Patrizia Celli | Maurizio Ferrario | Flavio Ribichini | Marco Rossi | Pietro Zonzin | Jean Yee | Gavin Lucas | Rafael Ramos | Joshua M Korn | Daniel Mirel | Patrick Linsel-Nitschke | Inke König | Marcus Fischer | Michael Scholz | Zhen Chen | Joe Devaney | Mary-Susan Burnett | Lowell Satler | Pascal McKeown | Erdmann Erdmann | M. Spreafico | A. Huge | G. Williams | M. Walker | S. Schreiber | P. Celli | R. Elosúa | Jean Yee | R. Ramos | Zhen Chen | E. Erdmann | P. Mckeown | M. Preuss | A. Grosshennig

[1]  S. Cichon,et al.  Corrigendum: Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis , 2009, Nature Genetics.

[2]  Daniel F. Schwarz,et al.  New susceptibility locus for coronary artery disease on chromosome 3q22.3 , 2009, Nature Genetics.

[3]  D. Mozaffarian,et al.  Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. , 2009, Circulation.

[4]  B. Frey,et al.  Addendum: Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing , 2009, Nature Genetics.

[5]  Judy H. Cho,et al.  Corrigendum: Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants , 2009, Nature Genetics.

[6]  R. Collins,et al.  Common variants at 30 loci contribute to polygenic dyslipidemia , 2009, Nature Genetics.

[7]  Joshua M. Korn,et al.  Integrated detection and population-genetic analysis of SNPs and copy number variation , 2008, Nature Genetics.

[8]  Joshua M. Korn,et al.  Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs , 2008, Nature Genetics.

[9]  P. Visscher,et al.  Rare chromosomal deletions and duplications increase risk of schizophrenia , 2008, Nature.

[10]  C. Gieger,et al.  Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study , 2008, PloS one.

[11]  S. Kathiresan,et al.  Polymorphisms Associated With Cholesterol and Risk of Cardiovascular Events , 2008 .

[12]  S. Kathiresan A PCSK9 missense variant associated with a reduced risk of early-onset myocardial infarction. , 2008, The New England journal of medicine.

[13]  M. Daly,et al.  Estimation of the multiple testing burden for genomewide association studies of nearly all common variants , 2008, Genetic epidemiology.

[14]  M. McCarthy,et al.  Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes , 2008, Nature Genetics.

[15]  R. Collins,et al.  Newly identified loci that influence lipid concentrations and risk of coronary artery disease , 2008, Nature Genetics.

[16]  Dolores Corella,et al.  Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans , 2008, Nature Genetics.

[17]  K. Furie,et al.  Heart disease and stroke statistics--2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. , 2007, Circulation.

[18]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[19]  C. Gieger,et al.  Genomewide association analysis of coronary artery disease. , 2007, The New England journal of medicine.

[20]  A. Gylfason,et al.  A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction , 2007, Science.

[21]  Jonathan C. Cohen,et al.  A Common Allele on Chromosome 9 Associated with Coronary Heart Disease , 2007, Science.

[22]  D. Labarthe,et al.  Prevalence of heart disease--United States, 2005. , 2007, MMWR. Morbidity and mortality weekly report.

[23]  Jonathan C. Cohen,et al.  Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. , 2006, The New England journal of medicine.

[24]  N. Cook,et al.  Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women. , 2005, JAMA.

[25]  E. Kremmer,et al.  Mammalian WDR12 is a novel member of the Pes1–Bop1 complex and is required for ribosome biogenesis and cell proliferation , 2005, The Journal of cell biology.

[26]  Kenny Q. Ye,et al.  Large-Scale Copy Number Polymorphism in the Human Genome , 2004, Science.

[27]  Ralph B D'Agostino,et al.  Risk of complications of pregnancy in women with type 1 diabetes: nationwide prospective study in the Netherlands , 2004, BMJ : British Medical Journal.

[28]  P. Greengard,et al.  Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[29]  J. Weissenbach,et al.  Mutations in PCSK9 cause autosomal dominant hypercholesterolemia , 2003, Nature Genetics.

[30]  L. Spremulli,et al.  The Small Subunit of the Mammalian Mitochondrial Ribosome , 2001, The Journal of Biological Chemistry.

[31]  M. Keating,et al.  MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia , 1999, Cell.

[32]  A. Yamauchi,et al.  Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein. , 1992, The Journal of biological chemistry.

[33]  H. Hobbs,et al.  Molecular genetics of the LDL receptor gene in familial hypercholesterolemia , 1992, Human mutation.

[34]  W. Kimberling,et al.  Genetic–Epidemiologic Study of Early–onset Ischemic Heart Disease , 1980, Circulation.