Prediction of relative position of CT slices using a computational intelligence system

Graphical abstractDisplay Omitted One of the most common techniques in radiology is the computerized tomography (CT) scan. Automatically determining the relative position of a single CT slice within the human body can be very useful. It can allow for an efficient retrieval of slices from the same body region taken in other volume scans and provide useful information to the non-expert user. This work addresses the problem of determining which portion of the body is shown by a stack of axial CT image slices. To tackle this problem, this work proposes a computational intelligence system that combines semantics-based operators for Genetic Programming with a local search algorithm, coupling the exploration ability of the former with the exploitation ability of the latter. This allows the search process to quickly converge towards (near-)optimal solutions. Experimental results, using a large database of CT images, have confirmed the suitability of the proposed system for the prediction of the relative position of a CT slice. In particular, the new method achieves a median localization error of 3.4cm on unseen data, outperforming standard Genetic Programming and other techniques that have been applied to the same dataset. In summary, this paper makes two contributions: (i) in the radiology domain, the proposed system outperforms current state-of-the-art techniques; (ii) from the computational intelligence perspective, the results show that including a local searcher in Geometric Semantic Genetic Programming can speed up convergence without degrading test performance.