Relationship of Blood Heparin Levels to Serum Lipoproteins and Cholesterol Levels in Fasting Subjects.∗

Summary 1. A highly reproducible modification of the Bassiouni method for determination of spontaneously-occurring blood heparin-like substances has been described and evaluated. 2. A mean level of 3.07 mg/100 ml of blood heparin-like substances was determined for a sample of 105 fasting U.S. schizophrenic males 40 to 50 years old. This sample group showed lipoprotein and cholesterol values very close to those characteristic for other samples of U.S. males previously studied. 3. Highly significant negative correlations were demonstrated for the following pairs of variables, Sf° 0-12 lipoproteins versus blood “heparin,” Sf° 12-20 lipoproteins versus blood “heparin,” and serum cholesterol versus blood “heparin.”