Microenvironment in Acute Myeloid Leukemia: focus on senescence mechanisms, therapeutic interactions and future directions.
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M. Voso | E. Fabiani | G. Falconi | A. Cristiano | E. Galossi | Luca Guarnera | Enrico Santinelli | L. Guarnera
[1] S. Pervaiz,et al. Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD , 2023, Biology.
[2] K. Mrozik,et al. Mesenchymal stromal cell senescence in haematological malignancies , 2023, Cancer and Metastasis Reviews.
[3] M. Voso,et al. Impairment of FOXM1 expression in mesenchymal cells from patients with myeloid neoplasms, de novo and therapy-related, may compromise their ability to support hematopoiesis , 2022, Scientific reports.
[4] Sharad Kumar,et al. A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure , 2022, Leukemia.
[5] L. Lerman,et al. Cellular senescence: the good, the bad and the unknown , 2022, Nature Reviews Nephrology.
[6] C. Zhan,et al. The immunomodulatory role of all-trans retinoic acid in tumor microenvironment , 2022, Clinical and Experimental Medicine.
[7] B. Ebert,et al. Diagnosis and Management of AML in Adults: 2022 ELN Recommendations from an International Expert Panel. , 2022, Blood.
[8] C. Drenberg,et al. Lymphocyte Exhaustion in AML Patients and Impacts of HMA/Venetoclax or Intensive Chemotherapy on Their Biology , 2022, Cancers.
[9] M. Salazar-Terreros,et al. In Vitro and In Vivo Modeling of Normal and Leukemic Bone Marrow Niches: Cellular Senescence Contribution to Leukemia Induction and Progression , 2022, International journal of molecular sciences.
[10] P. Pedrazzoli,et al. Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022 , 2022, Bone Marrow Transplantation.
[11] M. Konopleva,et al. Venetoclax combined with FLAG‐IDA induction and consolidation in newly diagnosed acute myeloid leukemia , 2022, American journal of hematology.
[12] J. Vernot,et al. Bone Marrow Aging and the Leukaemia-Induced Senescence of Mesenchymal Stem/Stromal Cells: Exploring Similarities , 2022, Journal of personalized medicine.
[13] M. Voso,et al. Atypical Rearrangements in APL-Like Acute Myeloid Leukemias: Molecular Characterization and Prognosis , 2022, Frontiers in Oncology.
[14] S. Haas,et al. Cancer stem cells: The adventurous journey from hematopoietic to leukemic stem cells , 2022, Cell.
[15] A. Tzankov,et al. Tumor Microenvironment in Acute Myeloid Leukemia: Adjusting Niches , 2022, Frontiers in Immunology.
[16] M. Aurrand-Lions,et al. Adhesion Molecules Involved in Stem Cell Niche Retention During Normal Haematopoiesis and in Acute Myeloid Leukaemia , 2021, Frontiers in Immunology.
[17] Sandra Pinho,et al. Leukemic Stem Cells: From Leukemic Niche Biology to Treatment Opportunities , 2021, Frontiers in Immunology.
[18] Yangqiu Li,et al. TIM-3 in Leukemia; Immune Response and Beyond , 2021, Frontiers in Oncology.
[19] Kevin M. Woods,et al. Dynamic Changes of the Bone Marrow Niche: Mesenchymal Stromal Cells and Their Progeny During Aging and Leukemia , 2021, Frontiers in Cell and Developmental Biology.
[20] M. Serafini,et al. Catch me if you can: how AML and its niche escape immunotherapy , 2021, Leukemia.
[21] Jian Huang,et al. Leukemia stem cell-bone marrow microenvironment interplay in acute myeloid leukemia development , 2021, Experimental Hematology & Oncology.
[22] M. Guzman,et al. Macrophages in Acute Myeloid Leukaemia: Significant Players in Therapy Resistance and Patient Outcomes , 2021, Frontiers in Cell and Developmental Biology.
[23] Y. Kawakami,et al. Cascade of Inflammatory, Fibrotic Processes, and Stress-Induced Senescence in Chronic GVHD-Related Dry Eye Disease , 2021, International journal of molecular sciences.
[24] H. Kantarjian,et al. Acute Myeloid Leukemia: Historical Perspective and Progress in Research and Therapy Over 5 Decades. , 2021, Clinical lymphoma, myeloma & leukemia.
[25] H. Kantarjian,et al. De novo acute myeloid leukemia: A population‐based study of outcome in the United States based on the Surveillance, Epidemiology, and End Results (SEER) database, 1980 to 2017 , 2021, Cancer.
[26] M. Minden,et al. Venetoclax enhances T cell-mediated anti-leukemic activity by increasing ROS production. , 2021, Blood.
[27] R. Darley,et al. Reactive Oxygen Species Rewires Metabolic Activity in Acute Myeloid Leukemia , 2021, Frontiers in Oncology.
[28] S. Yamasaki,et al. Relapse of acute myeloid leukemia after allogeneic hematopoietic cell transplantation: clinical features and outcomes , 2020, Bone Marrow Transplantation.
[29] Saeid Taghiloo,et al. Immune evasion mechanisms in acute myeloid leukemia: A focus on immune checkpoint pathways. , 2020, Critical reviews in oncology/hematology.
[30] J. Welch,et al. 10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial. , 2020, The Lancet. Haematology.
[31] A. Letai,et al. Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia. , 2020, The New England journal of medicine.
[32] K. Strauch,et al. Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN). , 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[33] H. Okano,et al. Senescence‐associated secretory phenotype promotes chronic ocular graft‐vs‐host disease in mice and humans , 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[34] D. Huang,et al. Arsenic trioxide and all-trans retinoic acid suppress the expression of FLT3-ITD , 2020, Leukemia & lymphoma.
[35] M. Voso,et al. When Poisons Cure: The Case of Arsenic in Acute Promyelocytic Leukemia , 2020, Chemotherapy.
[36] Yimei Hong,et al. Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges , 2020, Frontiers in Cell and Developmental Biology.
[37] J. Vernot. Senescence-Associated Pro-inflammatory Cytokines and Tumor Cell Plasticity , 2020, Frontiers in Molecular Biosciences.
[38] Q. Niu,et al. Role of PML SUMOylation in arsenic trioxide-induced fibrosis in HSCs. , 2020, Life sciences.
[39] Yue Han,et al. Comparative efficacy of 20 graft-versus-host disease prophylaxis therapies for patients after hematopoietic stem-cell transplantation: A multiple-treatments network meta-analysis. , 2020, Critical reviews in oncology/hematology.
[40] J. Gribben,et al. Bone marrow niches in haematological malignancies , 2020, Nature Reviews Cancer.
[41] Guoji Guo,et al. Live-animal imaging of native hematopoietic stem and progenitor cells , 2019, Nature.
[42] R. Larson,et al. Gilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AML. , 2019, The New England journal of medicine.
[43] N. Schmitz,et al. Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial , 2019, Leukemia.
[44] M. Martelli,et al. The “ultimate” haploidentical transplantation for the elderly with high-risk acute myeloid leukemia , 2019, Bone Marrow Transplantation.
[45] M. Caligiuri,et al. Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion , 2019, Nature.
[46] H. Dombret,et al. Quizartinib versus salvage chemotherapy in relapsed or refractory FLT3-ITD acute myeloid leukaemia (QuANTUM-R): a multicentre, randomised, controlled, open-label, phase 3 trial. , 2019, The Lancet. Oncology.
[47] Y. Kong. Poor graft function after allogeneic hematopoietic stem cell transplantation-an old complication with new insights☆. , 2019, Seminars in hematology.
[48] Monika S. Kowalczyk,et al. A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia , 2019, Cell.
[49] L. Bullinger,et al. NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML. , 2019, Blood.
[50] P. Frenette,et al. Haematopoietic stem cell activity and interactions with the niche , 2019, Nature Reviews Molecular Cell Biology.
[51] O. Lyublinskaya,et al. High doses of synthetic antioxidants induce premature senescence in cultivated mesenchymal stem cells , 2019, Scientific Reports.
[52] R. Schlenk,et al. Targeting FLT3 mutations in AML: review of current knowledge and evidence , 2019, Leukemia.
[53] U. Germing,et al. Relapse of Acute Myeloid Leukemia after Allogeneic Stem Cell Transplantation: Prevention, Detection, and Treatment , 2019, International journal of molecular sciences.
[54] W. Faridi,et al. Significant Risk of Graft-versus-Host Disease with Exposure to Checkpoint Inhibitors before and after Allogeneic Transplantation. , 2019, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[55] Xi C. He,et al. N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells. , 2019, Cell reports.
[56] Miran Jang,et al. Midostaurin reduces Regulatory T cells markers in Acute Myeloid Leukemia , 2018, Scientific Reports.
[57] Yu Wang,et al. Dysfunctional Bone Marrow Mesenchymal Stem Cells in Patients with Poor Graft Function after Allogeneic Hematopoietic Stem Cell Transplantation. , 2018, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[58] R. Medema,et al. FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence , 2018, Nature Communications.
[59] Yu Wang,et al. An unbalanced monocyte macrophage polarization in the bone marrow microenvironment of patients with poor graft function after allogeneic haematopoietic stem cell transplantation , 2018, British journal of haematology.
[60] T. Jaffredo,et al. The crosstalk between hematopoietic stem cells and their niches , 2018, Current opinion in hematology.
[61] J. Wagner,et al. First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation. , 2018, Blood.
[62] L. Raida,et al. Graft versus Host Disease: From Basic Pathogenic Principles to DNA Damage Response and Cellular Senescence , 2018, Mediators of inflammation.
[63] K. Tsubota,et al. Inhibition of Vascular Adhesion Protein‐1 for Treatment of Graft‐Versus‐Host Disease in Mice , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[64] M. Caligiuri,et al. Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells , 2018, Nature Medicine.
[65] F. Rosenbauer,et al. Bone marrow laminins influence hematopoietic stem and progenitor cell cycling and homing to the bone marrow. , 2018, Matrix biology : journal of the International Society for Matrix Biology.
[66] Atul Kumar,et al. Mesenchymal stem cells show functional defect and decreased anti-cancer effect after exposure to chemotherapeutic drugs , 2018, Journal of Biomedical Science.
[67] Catriona McLean,et al. Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML , 2018, Cell stem cell.
[68] B. Leber,et al. Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche , 2017, Nature Cell Biology.
[69] D. Edwards,et al. NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts. , 2017, Blood.
[70] J. Gribben,et al. Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia , 2017, Cancer cell.
[71] F. Locatelli,et al. Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion. , 2017, Blood.
[72] R. Davis,et al. AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth. , 2017, JCI insight.
[73] C. Bloomfield,et al. Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation , 2017, The New England journal of medicine.
[74] M. L. Le Beau,et al. Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apcdel/+ MDS mouse model. , 2017, Blood.
[75] K. Tarte,et al. Alteration Analysis of Bone Marrow Mesenchymal Stromal Cells from De Novo Acute Myeloid Leukemia Patients at Diagnosis. , 2017, Stem cells and development.
[76] Xue-Qun Luo,et al. Arsenic trioxide and all-trans-retinoic acid selectively exert synergistic cytotoxicity against FLT3-ITD AML cells via co-inhibition of FLT3 signaling pathways , 2017, Leukemia & lymphoma.
[77] K. Tsubota,et al. Novel Treatment of Chronic Graft-Versus-Host Disease in Mice Using the ER Stress Reducer 4-Phenylbutyric Acid , 2017, Scientific Reports.
[78] M. Lohoff,et al. PD-1 checkpoint blockade in patients with relapsed AML after allogeneic stem cell transplantation , 2017, Bone Marrow Transplantation.
[79] J. Ritz,et al. The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. , 2017, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[80] Queen Intan Nurrahmah,et al. Arsenic trioxide induces ROS activity and DNA damage, leading to G0/G1 extension in skin fibroblasts through the ATM-ATR-associated Chk pathway , 2017, Environmental Science and Pollution Research.
[81] N. Myakova,et al. Tcrαβ+/CD19+-Depletion in Hematopoietic Stem Cells Transplantation from Matched Unrelated and Haploidentical Donors Following Treosulfan or TBI-Based Conditioning in Pediatric Acute Lymphoblastic Leukemia Patients , 2016 .
[82] D. Scadden,et al. Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment , 2016, Nature.
[83] Xiao-hui Zhang,et al. Increased Type 1 Immune Response in the Bone Marrow Immune Microenvironment of Patients with Poor Graft Function after Allogeneic Hematopoietic Stem Cell Transplantation. , 2016, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[84] Philip R. Gafken,et al. Biomarker Panel for Chronic Graft-Versus-Host Disease. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[85] V. Imbert,et al. Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy. , 2016, Blood.
[86] F. Hodi,et al. Ipilimumab for Patients with Relapse after Allogeneic Transplantation. , 2016, The New England journal of medicine.
[87] N. Kröger,et al. Incidence and risk factors of poor graft function after allogeneic stem cell transplantation for myelofibrosis , 2016, Bone Marrow Transplantation.
[88] Fadwa Said,et al. Indoleamine 2,3-dioxygenase and regulatory T cells in acute myeloid leukemia , 2016, Hematology.
[89] Xiao-hui Zhang,et al. The bone marrow microenvironment is similarly impaired in allogeneic hematopoietic stem cell transplantation patients with early and late poor graft function , 2016, Bone Marrow Transplantation.
[90] V. Bobrynina,et al. TCR-alpha/beta and CD19 depletion and treosulfan-based conditioning regimen in unrelated and haploidentical transplantation in children with acute myeloid leukemia , 2016, Bone Marrow Transplantation.
[91] D. Link,et al. The hematopoietic stem cell niche in homeostasis and disease. , 2015, Blood.
[92] R. Hills,et al. Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial. , 2015, The Lancet. Oncology.
[93] Yu-Hong Chen,et al. The incidence, risk factors, and outcomes of primary poor graft function after unmanipulated haploidentical stem cell transplantation , 2015, Annals of Hematology.
[94] Baojie Li,et al. Mesenchymal stem cell aging: Mechanisms and influences on skeletal and non-skeletal tissues , 2015, Experimental biology and medicine.
[95] Jace W. Jones,et al. All-Trans Retinoic Acid Activity in Acute Myeloid Leukemia: Role of Cytochrome P450 Enzyme Expression by the Microenvironment , 2015, PloS one.
[96] M. Ebinger,et al. Improved immune recovery after transplantation of TCRαβ/CD19-depleted allografts from haploidentical donors in pediatric patients , 2015, Bone Marrow Transplantation.
[97] H. Dombret,et al. Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells. , 2015, Blood.
[98] B. Falini,et al. Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells. , 2015, Blood.
[99] P. Frenette,et al. Making sense of hematopoietic stem cell niches. , 2015, Blood.
[100] P. Bianco,et al. Skeletal stem cells , 2015, Development.
[101] M. Pasquini,et al. Primary Graft Failure after Myeloablative Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies , 2015, Leukemia.
[102] C. Preudhomme,et al. Prognosis and monitoring of core-binding factor acute myeloid leukemia: current and emerging factors , 2015, Expert review of hematology.
[103] S. Armstrong,et al. Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche. , 2014, Cell stem cell.
[104] B. Falini,et al. HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse. , 2014, Blood.
[105] B. Isermann,et al. Clinically relevant doses of FLT3-kinase inhibitors quizartinib and midostaurin do not impair T-cell reactivity and function , 2014, Haematologica.
[106] J. Schwaller,et al. CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia , 2014, Leukemia.
[107] K. Tsai,et al. Effects of Arsenic on Osteoblast Differentiation in Vitro and on Bone Mineral Density and Microstructure in Rats , 2014, Environmental health perspectives.
[108] S. Morrison,et al. The bone marrow niche for haematopoietic stem cells , 2014, Nature.
[109] Yan-rong Liu,et al. Association of an impaired bone marrow microenvironment with secondary poor graft function after allogeneic hematopoietic stem cell transplantation. , 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[110] D. Blaise,et al. Outcome of relapse after allogeneic stem cell transplant in patients with acute myeloid leukemia , 2013, Leukemia & lymphoma.
[111] M. Remberger,et al. Graft failure in the modern era of allogeneic hematopoietic SCT , 2013, Bone Marrow Transplantation.
[112] A. Jemal,et al. Cancer statistics, 2013 , 2013, CA: a cancer journal for clinicians.
[113] F. Goldwasser,et al. Arsenic Trioxide Exerts Antitumor Activity through Regulatory T Cell Depletion Mediated by Oxidative Stress in a Murine Model of Colon Cancer , 2012, The Journal of Immunology.
[114] T. Suda,et al. Role of N‐cadherin in the regulation of hematopoietic stem cells in the bone marrow niche , 2012, Annals of the New York Academy of Sciences.
[115] A. Salminen,et al. Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP). , 2012, Cellular signalling.
[116] Kazuhiro Morishita,et al. The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1high Leukemia , 2012, PloS one.
[117] Susan E. Murray,et al. NF-κB–inducing kinase plays an essential T cell–intrinsic role in graft-versus-host disease and lethal autoimmunity in mice. , 2011, The Journal of clinical investigation.
[118] T. Wynn,et al. Protective and pathogenic functions of macrophage subsets , 2011, Nature Reviews Immunology.
[119] Hongwei Ma,et al. Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1. , 2011, Blood.
[120] Charles P. Lin,et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche , 2011, Nature.
[121] D. Wiseman. Donor cell leukemia: a review. , 2011, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[122] B. Falini,et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. , 2011, Blood.
[123] A. Tefferi,et al. Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis: a comprehensive cytokine profiling study. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[124] H. Zhang,et al. Arsenic trioxide promotes senescence and regulates the balance of adipogenic and osteogenic differentiation in human mesenchymal stem cells. , 2011, Acta biochimica et biophysica Sinica.
[125] J. Bartek,et al. Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16ink4a , 2011, Cell cycle.
[126] Kelly Sanders,et al. Alkylating chemotherapeutic agents cyclophosphamide and melphalan cause functional injury to human bone marrow-derived mesenchymal stem cells , 2011, Annals of Hematology.
[127] Ben D. MacArthur,et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche , 2010, Nature.
[128] S. Kashima,et al. Effects of high-dose chemotherapy on bone marrow multipotent mesenchymal stromal cells isolated from lymphoma patients. , 2010, Experimental hematology.
[129] Ya-Wen Chen,et al. Arsenic induces cell apoptosis in cultured osteoblasts through endoplasmic reticulum stress. , 2009, Toxicology and applied pharmacology.
[130] T. Gajewski,et al. PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model. , 2009, Blood.
[131] E. Holler,et al. Graft-versus-host disease , 2009, The Lancet.
[132] B. Pulendran,et al. TLR2 dependent induction of vitamin A metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits TH-17 mediated autoimmunity , 2009, Nature Medicine.
[133] J. Serody,et al. Ex vivo Inhibition of NF‐κB Signaling in Alloreactive T‐cells Prevents Graft‐Versus‐Host Disease , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[134] S. Fröhling,et al. Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia. Results from the AMLSG Trial AML HD98B , 2009, Haematologica.
[135] Judith Campisi,et al. Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor , 2008, PLoS biology.
[136] H. Döhner,et al. Dasatinib exerts an immunosuppressive effect on CD8+ T cells specific for viral and leukemia antigens. , 2008, Experimental hematology.
[137] V. Beneš,et al. Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process , 2008, PloS one.
[138] Daniel Lucas,et al. Haematopoietic stem cell release is regulated by circadian oscillations , 2008, Nature.
[139] M. Rojewski,et al. Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling , 2008, Journal of cellular and molecular medicine.
[140] Satoshi Tanaka,et al. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region , 2007, Nature Biotechnology.
[141] R. Shirkoohi,et al. All-trans Retinoic Acid Enhances Murine Dendritic Cell Migration to Draining Lymph Nodes via the Balance of Matrix Metalloproteinases and Their Inhibitors1 , 2007, The Journal of Immunology.
[142] J. Campisi,et al. Cellular senescence: when bad things happen to good cells , 2007, Nature Reviews Molecular Cell Biology.
[143] M. Lübbert,et al. CXCR4 is a prognostic marker in acute myelogenous leukemia. , 2007, Blood.
[144] M. Graf,et al. Expression of MAC‐1 (CD11b) in acute myeloid leukemia (AML) is associated with an unfavorable prognosis , 2006, American journal of hematology.
[145] P. Hari,et al. NF-kappaB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145. , 2006, Blood.
[146] S. Jalkanen,et al. Cell-surface enzymes in control of leukocyte trafficking , 2005, Nature Reviews Immunology.
[147] Y. Ko,et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size , 2005, The Journal of experimental medicine.
[148] A. Hanash,et al. Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation. , 2005, Blood.
[149] Hans Clevers,et al. FoxM1 is required for execution of the mitotic programme and chromosome stability , 2005, Nature Cell Biology.
[150] R. Handgretinger,et al. Human γδ T Cells From G-CSF-Mobilized Donors Retain Strong Tumoricidal Activity and Produce Immunomodulatory Cytokines After Clinical-Scale Isolation , 2005 .
[151] L. Verdonck,et al. Extra-domain-A fibronectin: a new marker of fibrosis in cutaneous graft-versus-host disease. , 2004, The Journal of investigative dermatology.
[152] H. Drexler,et al. Mini ReviewFLT3: Receptor and Ligand , 2004 .
[153] D. Klatzmann,et al. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. , 2003, The Journal of clinical investigation.
[154] C. Fathman,et al. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation , 2003, Nature Medicine.
[155] H. Kuroda,et al. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia , 2003, Nature Medicine.
[156] D. Gabrilovich,et al. Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species , 2003, Journal of leukocyte biology.
[157] A. Venditti,et al. Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML). , 2003, Blood.
[158] David Klatzmann,et al. CD4+CD25+ Immunoregulatory T Cells , 2002, The Journal of experimental medicine.
[159] B. Blazar,et al. The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. , 2002, Blood.
[160] P. Chilton,et al. The role of alphabeta- and gammadelta-T cells in allogenic donor marrow on engraftment, chimerism, and graft-versus-host disease. , 2001, Transplantation.
[161] S. Ferrari,et al. Induction of a functional vitamin D receptor in all-trans-retinoic acid-induced monocytic differentiation of M2-type leukemic blast cells. , 1999, Cancer research.
[162] J. Jönsson,et al. Characterization of Bone Marrow Laminins and Identification of 5-Containing Laminins as Adhesive Proteins for Multipotent Hematopoietic FDCP-Mix Cells , 1999 .
[163] H. Kluin-Nelemans,et al. A strong expression of CD44-6v correlates with shorter survival of patients with acute myeloid leukemia. , 1998, Blood.
[164] J. Dick,et al. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell , 1997, Nature Medicine.
[165] S. Ergün,et al. Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukemia. , 1997, Blood.
[166] T. Naoe,et al. In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins , 1996 .
[167] E. Schiavone,et al. All‐trans retinoic acid promotes a differential regulation of adhesion molecules on acute myeloid leukaemia blast cells , 1994, British journal of haematology.
[168] M. Caligiuri,et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice , 1994, Nature.
[169] J. Magaud,et al. High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy. , 1993, Blood.
[170] Zhen-yi Wang,et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. , 1988, Haematology and blood transfusion.
[171] A. Butturini,et al. Graft-versus-leukemia following bone marrow transplantation. , 1987, Bone marrow transplantation.
[172] R. Elashoff,et al. Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease. A prospective, randomized, double-blind trial. , 1986, Annals of internal medicine.
[173] A. Boskey,et al. Bone structure, composition, and mineralization. , 1984, The Orthopedic clinics of North America.
[174] M. Voso,et al. Impairment of PI3K/AKT and WNT/β-catenin pathways in bone marrow mesenchymal stem cells isolated from patients with myelodysplastic syndromes. , 2016, Experimental hematology.
[175] D. Scadden,et al. Hematopoietic Stem Cell and Its Bone Marrow Niche. , 2016, Current topics in developmental biology.
[176] S. Nimmagadda,et al. The intricate role of CXCR4 in cancer. , 2014, Advances in cancer research.
[177] E. Lam,et al. FOXM1: From cancer initiation to progression and treatment. , 2012, Biochimica et biophysica acta.
[178] David W. Rowe,et al. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche , 2009, Nature.
[179] René H Medema,et al. FoxM1: at the crossroads of ageing and cancer. , 2007, Biochimica et biophysica acta.
[180] P. Fung,et al. Plasma nitric oxide is associated with the occurrence of moderate to severe acute graft-versus-host disease in haemopoietic stem cell transplant recipients. , 2001, Haematologica.
[181] J. Sosman,et al. The graft versus leukemia effect: possible mechanisms and clinical significance to the biologic therapy of leukemia. , 1991, Bone marrow transplantation.
[182] K. Sullivan,et al. Graft versus leukemia effect in man: the relapse rate of acute leukemia is lower after allogeneic than after syngeneic marrow transplantation. , 1987, Progress in clinical and biological research.
[183] H. Deeg,et al. Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts. , 1985, Blood.