Methods for assessing the bioligical activity of the mammalian pineal organ.

[1]  R. Wurtman,et al.  Fate of intracisternally injected melatonin in the rat brain. , 1973, Neuroendocrinology.

[2]  R. Wurtman,et al.  Binding of melatonin to human and rat plasma proteins. , 1972, Endocrinology.

[3]  T. Deguchi,et al.  Sensitive assay for serotonin N-acetyltransferase activity in rat pineal. , 1972, Analytical biochemistry.

[4]  S. Koslow,et al.  Gas Chromatographic-Mass Spectrometric Assay of Four Indole Alkylamines of Rat Pineal , 1972, Science.

[5]  R. Wurtman,et al.  Action spectra for effects of light on hydroxyindole-o-methyl transferases in rat pineal, retina and harderian gland. , 1972, Endocrinology.

[6]  D. Cardinali,et al.  Direct action of light on serotonin metabolism and RNA biosynthesis in duck pineal explants. , 1972, Life sciences. Pt. 2: Biochemistry, general and molecular biology.

[7]  D. Cardinali,et al.  Light regulation of rat retinal hydroxyindole-O-methyl transferase (HIOMT) activity. , 1972, Endocrinology.

[8]  R. Wurtman,et al.  Hydroxyindole-O-methyl transferases in rat pineal, retina and harderian gland. , 1972, Endocrinology.

[9]  A. Jaussi,et al.  Correlation of age changes in monoamine oxidase activity and androgen synthesis by rat testicular minced and teased-tubular preparations in vitro. , 1972, Endocrinology.

[10]  B. Weiss,et al.  Effect of norepinephrine on the concentration of adenosine 3',5'-monophosphate of rat pineal gland in organ culture. , 1972, Endocrinology.

[11]  A. Rodin,et al.  Studies on a non-melatonin pineal anti-gonadotrophin. , 1972, Acta endocrinologica.

[12]  J. Barchas,et al.  A gas-liquid chromatographic assay of melatonin and indoleamines using heptafluorobutyryl derivatives. , 1972, Analytical biochemistry.

[13]  R. Wurtman,et al.  A Mg 2+ dependent hydroxyindole O-methyltransferase in rat Harderian gland. , 1972, Biochimica et biophysica acta.

[14]  C. Thornburn,et al.  Toxicity of the taste testing compound phenylthiocarbamide. , 1972, Nature: New biology.

[15]  J. Axelrod,et al.  The pineal gland. , 1970, Endeavour.

[16]  C. Ellislegrande.  Inhibition of rat testicular androgen synthesis in vitro by melantonin and serotonin. , 1972 .

[17]  C. W. Turner,et al.  Effect of melatonin upon thyroid hormone secretion rate in female hamsters and male rats. , 1972, Acta endocrinologica.

[18]  C. L. Ralph,et al.  A melatonin rhythm persists in rat pineals in darkness. , 1971, Endocrinology.

[19]  D. Cardinali,et al.  Direct effect of light on duck pineal explants. , 1971, Life sciences. Pt. 2: Biochemistry, general and molecular biology.

[20]  C. Goridis,et al.  Evidence for a specific monoamine oxidase associated with sympathetic nerves. , 1971, Neuropharmacology.

[21]  D. Cardinali,et al.  Metabolism of serotonin by the rat retina in vitro , 1971, Journal of neurochemistry.

[22]  W. Lovenberg,et al.  Rapid analysis of tryptophan hydroxylase in rat tissue using 5- 3 H-tryptophan. , 1971, Analytical biochemistry.

[23]  R. Wurtman,et al.  MEDIATION BY β‐ADRENERGIC RECEPTORS OF EFFECT OF NOREPINEPHRINE ON PINEAL SYNTHESIS OF [14C]SEROTONIN AND [14C]MELATONIN , 1971, Journal of neurochemistry.

[24]  H. Lynch.  Diurnal oscillations in pineal melatonin content. , 1971, Life sciences. Pt. 1: Physiology and pharmacology.

[25]  W. Lovenberg,et al.  Isolation and characterization of multiple forms of hydroxyindole-O-methyltransferase. , 1971, The Journal of biological chemistry.

[26]  R. Wurtman,et al.  Brain Serotonin Content: Physiological Dependence on Plasma Tryptophan Levels , 1971, Science.

[27]  D. Cardinali,et al.  Effects of melatonin, serotonin and N-acetylserotonin on the production of steroids by duck testicular homogenates. , 1971, Steroids.

[28]  D. Cardinali,et al.  Retinal localization of the hydroxyindole-O-methyl transferase (HIOMT) in the rat. , 1971, Endocrinology.

[29]  J. C. Porter,et al.  Effects of melatonin and serotonin on the release of FSH and prolactin. , 1971, Endocrinology.

[30]  A. Rodin,et al.  A melatonin-free extract of bovine pineal with antigonadotropic activity. , 1971, Life sciences. Pt. 1: Physiology and pharmacology.

[31]  G. Crank,et al.  Tryptamines. I. The chromatography of melatonin. , 1971, Journal of chromatography.

[32]  F. Peat,et al.  Testicular steroidogeneis in vitro in the rat in response to blinding, pinealectomy and to the addition of melatonin. , 1971, Steroids.

[33]  L. Debeljuk,et al.  Effects of melatonin on changes induced by castration and testosterone in sexual structures of male rats. , 1970, Endocrinology.

[34]  C. L. Ralph,et al.  A quantitative melatonin bioassay. , 1970, General and comparative endocrinology.

[35]  J. Weller,et al.  Indole Metabolism in the Pineal Gland: A Circadian Rhythm in N-Acetyltransferase , 1970, Science.

[36]  R. P. Maickel,et al.  Fluorometric determination of indole derivatives. , 1970, Life sciences. Pt. 1: Physiology and pharmacology.

[37]  J. C. Porter,et al.  Effect of anterior pituitary perfusion and intraventricular injection of catecholamines and indoleamines on LH release. , 1970, Endocrinology.

[38]  Y. Nishizuka,et al.  Enzymic studies on the biosynthesis of serotonin in mammalian brain. , 1970, The Journal of biological chemistry.

[39]  R. Wurtman,et al.  Cyclic Adenosine Monophosphate: Stimulation of Melatonin and Serotonin Synthesis in Cultured Rat Pineals , 1969, Science.

[40]  M. Youdim,et al.  Multiple Forms of Rat Brain Monoamine Oxidase , 1969, Nature.

[41]  W. S. Marshall,et al.  Structural aspects of bretylium analogs and catecholamine depletion from the rat heart. , 1969, Life sciences.

[42]  R. Wurtman,et al.  Regional Uptake of 3H-Melatonin from Blood or Cerebrospinal Fluid by Rat Brain , 1969, Nature.

[43]  D. Klein,et al.  Thin-layer chromatographic separation of pineal gland derivatives of serotonin-14C. , 1969, Analytical biochemistry.

[44]  R. Wurtman,et al.  Brain Serotonin Concentration: Elevation Following Intraperitoneal Administration of Melatonin , 1968, Science.

[45]  B. Weiss,et al.  SELECTIVE STIMULATION OF ADENYL CYCLASE OF RAT PINEAL GLAND BY PHARMACOLOGICALLY ACTIVE CATECHOLAMINES , 1968 .

[46]  R. Wurtman,et al.  Formation of Melatonin and 5-Hydroxyindole Acetic Acid from 14C-Tryptophan by Rat Pineal Glands in Organ Culture , 1968, Nature.

[47]  S. Pennington.  A note on the chromatography of melatonin. , 1968, Journal of chromatography.

[48]  Y. Nishizuka,et al.  Tryptophan-5-hydroxylase in mammalian brain. , 1968, Advances in pharmacology.

[49]  W. Lovenberg,et al.  Tryptophan hydroxylation in mammalian systems. , 1968, Advances in pharmacology.

[50]  C. Owman,et al.  Activities of tryptophan hydroxylase, dopa decarboxylase, and monoamine oxidase as correlated with the appearance of monoamines in developing rat pineal gland. , 1967, Life sciences.

[51]  B. Singer,et al.  Effect of chronic pinealectomy on adrenocortical hormone secretion rates in normal and hypertensive rats. , 1967, General and comparative endocrinology.

[52]  A. Kastin,et al.  Autoregulation of Release of Melanocyte Stimulating Hormone from the Rat Pituitary , 1967, Nature.

[53]  J. Axelrod,et al.  Synthesis of Serotonin by Pineal Glands of the Rat in Organ Culture , 1967, Nature.

[54]  W. Lovenberg,et al.  Tryptophan Hydroxylation: Measurement in Pineal Gland, Brainstem, and Carcinoid Tumor , 1967, Science.

[55]  M. Greer,et al.  Gas-chromatographic determination of melatonin and 6-hydroxymelatonin☆ , 1967 .

[56]  R. P. Maickel,et al.  Fluorescent products formed by reaction of indole derivatives and o-phthalaldehyde , 1966 .

[57]  P. Mcgeer,et al.  Circadian Rhythm in Pineal Tyrosine Hydroxylase , 1966, Science.

[58]  C. Owman,et al.  PINEAL DOPA DECARBOXYLASE AND MONOAMINE OXIDASE ACTIVITIES AS RELATED TO THE MONOAMINE STORES , 1966, Journal of neurochemistry.

[59]  R. Wurtman,et al.  A 24-hour rhythm in the content of norepinephrine in the pineal and salivary glands of the rat. , 1966, Life sciences.

[60]  L. M. Zieher,et al.  Central control of noradrenaline content in rat pineal and submaxillary glands. , 1966, Life sciences.

[61]  L. M. Zieher,et al.  Noradrenaline and dopamine content of normal, decentralized and denervated pineal gland of the rat. , 1966, Life sciences.

[62]  S H Snyder,et al.  A sensitive and specific fluorescence assay for tissue serotonin. , 1965, Biochemical pharmacology.

[63]  S. Snyder,et al.  Evidence for the presence of monoamine oxidase in sympathetic nerve endings , 1965 .

[64]  S. Snyder,et al.  CONTROL OF 5-HYDROXYTRYPTOPHAN DECARBOXYLASE ACTIVITY IN THE RAT PINEAL GLAND BY SYMPATHETIC NERVES. , 1965, The Journal of pharmacology and experimental therapeutics.

[65]  S. Snyder,et al.  CONTROL OF HYDROXYINDOLE O-METHYLTRANSFERASE ACTIVITY IN THE RAT PINEAL GLAND BY ENVIRONMENTAL LIGHTING. , 1965, The Journal of biological chemistry.

[66]  E. Horning,et al.  Gas Chromatographic Studies of Catecholamines, Tryptamines, and Other Biological Amines. Part I. Catecholamines and Related Compounds. , 1964 .

[67]  A. Iraldi,et al.  5-Hydroxytryptophan-decarboxylase activity in normal and denervated pineal gland of rats☆ , 1964 .

[68]  S. Snyder,et al.  A SENSITIVE ASSAY FOR 5-HYDROXYTRYPTOPHAN DECARBOXYLASE. , 1964, Biochemical pharmacology.

[69]  R. Wurtman,et al.  Melatonin Synthesis in the Pineal Gland: Effect of Light Mediated by the Sympathetic Nervous System , 1964, Science.

[70]  R. Wurtman,et al.  THE UPTAKE OF H3-MELATONIN IN ENDOCRINE AND NERVOUS TISSUES AND THE EFFECTS OF CONSTANT LIGHT EXPOSURE. , 1964, The Journal of pharmacology and experimental therapeutics.

[71]  R. Wurtman,et al.  A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE. , 1963, Biochemical pharmacology.

[72]  L. S. Phillips,et al.  Melatonin Synthesis in thePineal Gland: Control by Light , 1963, Science.

[73]  R. Wurtman,et al.  Melatonin, a Pineal Substance: Effect on the Rat Ovary , 1963, Science.

[74]  W. B. Quay.  Differential extractions for the spectrophotofluorometric measurement of diverse 5-hydroxy- and 5-methoxyindoles. , 1963, Analytical biochemistry.

[75]  W. Lovenberg,et al.  Aromatic L-amino acid decarboxylase. , 1962, The Journal of biological chemistry.

[76]  S. Kveder,et al.  The metabolism of melatonin (N-acetyl-5-methoxytryptamine) and 5-methoxytryptamine. , 1961, The Journal of biological chemistry.

[77]  H. Weissbach,et al.  The enzymic acetylation of serotonin and other naturally ocurring amines , 1961 .

[78]  H. Weissbach,et al.  The fate of melatonin in animals. , 1961, The Journal of biological chemistry.

[79]  U. S. Euler,et al.  Improved technique for the fluorimetric estimation of catecholamines. , 1961, Acta physiologica Scandinavica.

[80]  H. Weissbach,et al.  Purification and properties of hydroxyindole-O-methyl transferase. , 1961, The Journal of biological chemistry.

[81]  A. Lerner,et al.  A MICROSCOPIC BTOASSAY FOR MELATONIN1 , 1960 .

[82]  H. Weissbach,et al.  6-Hydroxylation, the major metabolic pathway for melatonin. , 1960, Biochimica et biophysica acta.

[83]  A. Lerner,et al.  STRUCTURE OF MELATONIN1 , 1959 .

[84]  N. J. Giarman,et al.  Presence of biogenic amines in the bovine pineal body , 1959 .

[85]  B. Brodie,et al.  Identification and assay of serotonin in brain. , 1956, The Journal of pharmacology and experimental therapeutics.

[86]  V. M. Fiske.  EFFECT OF LIGHT ON SEXUAL MATURATION, ESTROUS CYCLES, AND ANTERIOR PITUITARY OF THE RAT1 , 1941 .

[87]  C. P. Mccord,et al.  Evidences associating pineal gland function with alterations in pigmentation , 1917 .