Autocorrelation of scattered laser light for ultrasound-modulated optical tomography in dense turbid media.

Based on measurement of the intensity autocorrelation function, a new method to determine the modulation depth of scattered laser light modulated by an ultrasonic wave in turbid media was applied to ultrasound-modulated optical tomography. Good signal-to-noise ratios and high sensitivities were demonstrated. Images of double optically absorbing objects buried in a highly optically scattering gel sample were obtained. The contrast was more than 10%, and the spatial resolution was approximately 2 mm.

[1]  Glen William Brooksby,et al.  Comprehensive approach to breast cancer detection using light: photon localization by ultrasound modulation and tissue characterization by spectral discrimination , 1993, Photonics West - Lasers and Applications in Science and Engineering.

[2]  G. Maret,et al.  Ultrasonic modulation of multiply scattered light , 1995 .

[3]  S L Jacques,et al.  Continuous-wave ultrasonic modulation of scattered laser light to image objects in turbid media. , 1995, Optics letters.

[4]  Azriel Z. Genack,et al.  Acousto-optic tomography with multiply scattered light , 1997 .

[5]  X. Zhao,et al.  Ultrasound-modulated optical tomography of absorbing objects buried in dense tissue-simulating turbid media. , 1997, Applied optics.

[6]  L V Wang,et al.  Frequency-swept ultrasound-modulated optical tomography of scattering media. , 1998, Optics letters.

[7]  G. Mahan,et al.  Ultrasonic tagging of light: theory. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[8]  A. Boccara,et al.  Ultrasonic tagging of photon paths in scattering media: parallel speckle modulation processing. , 1999, Optics letters.

[9]  L V Wang,et al.  Frequency-swept ultrasound-modulated optical tomography in biological tissue by use of parallel detection. , 2000, Optics letters.

[10]  L V Wang,et al.  Theoretical and experimental studies of ultrasound-modulated optical tomography in biological tissue. , 2000, Applied optics.

[11]  Z. Kotler,et al.  Ultrasound tagged light imaging in turbid media in a reflectance geometry. , 2000, Optics letters.

[12]  H U Voss,et al.  Dynamic long-term anticipation of chaotic states. , 2001, Physical review letters.

[13]  Lihong V. Wang.  Mechanisms of ultrasonic modulation of multiply scattered coherent light: an analytic model. , 2001 .

[14]  L V Wang,et al.  Mechanisms of ultrasonic modulation of multiply scattered coherent light: a Monte Carlo model. , 2001, Optics letters.