Cellular responses to reactive oxygen species-induced DNA damage and aging
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[1] A. Tomkinson,et al. Translocation of XRCC1 and DNA ligase IIIα from centrosomes to chromosomes in response to DNA damage in mitotic human cells , 2005, Nucleic acids research.
[2] J. Shay,et al. Senescence and immortalization: role of telomeres and telomerase. , 2005, Carcinogenesis.
[3] G. Kanbak,et al. Age‐related changes in the glutathione redox system , 2002, Cell biochemistry and function.
[4] K. Wirtz,et al. The Peroxisome in Oxidative Stress , 2001, IUBMB life.
[5] M. Kruhøffer,et al. Down-modulation of poly(ADP-ribose) polymerase-1 (PARP-1) in human TUR leukemia cells restores transcriptional responsiveness for differentiation and cell cycle arrest. , 2005, European journal of cell biology.
[6] H. Yamawaki,et al. Thioredoxin: a multifunctional antioxidant enzyme in kidney, heart and vessels , 2005, Current opinion in nephrology and hypertension.
[7] A. Bürkle,et al. Poly(ADP-ribosyl)ation in mammalian ageing , 2007, Nucleic acids research.
[8] W. de Laat,et al. Molecular mechanism of nucleotide excision repair. , 1999, Genes & development.
[9] M. Verhaar,et al. Understanding eNOS for pharmacological modulation of endothelial function: a translational view. , 2007, Current pharmaceutical design.
[10] I. Rahman,et al. Oxidative stress in asthma and COPD: antioxidants as a therapeutic strategy. , 2006, Pharmacology & therapeutics.
[11] D. Levy,et al. Growth, telomere dynamics and successful and unsuccessful human aging , 2003, Mechanisms of Ageing and Development.
[12] E. Kun,et al. Regulation of the enzymatic catalysis of poly(ADP-ribose) polymerase by dsDNA, polyamines, Mg2+, Ca2+, histones H1 and H3, and ATP. , 2004, Biochemistry.
[13] V. Ullrich,et al. Redox regulation of vascular prostanoid synthesis by the nitric oxide-superoxide system. , 2005, Biochemical and biophysical research communications.
[14] L. Hayflick. THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS. , 1965, Experimental cell research.
[15] A. Carrano,et al. Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange , 1990, Molecular and cellular biology.
[16] G. Dianov,et al. Replication protein A stimulates proliferating cell nuclear antigen-dependent repair of abasic sites in DNA by human cell extracts. , 1999, Biochemistry.
[17] K. Summer,et al. Responses of mitochondrial superoxide dismutase, catalase and glutathione peroxidase activities to aging , 1979, Mechanisms of Ageing and Development.
[18] P. Carvey,et al. Age-related changes in glutathione and glutathione-related enzymes in rat brain , 2006, Brain Research.
[19] Daniel Offen,et al. The role of oxidative stress in the pathogenesis of multiple sclerosis: The need for effective antioxidant therapy , 2004, Journal of Neurology.
[20] M. Blasco,et al. Cellular Senescence in Cancer and Aging , 2007, Cell.
[21] D. Harrison,et al. Extracellular superoxide dismutase and cardiovascular disease. , 2002, Cardiovascular research.
[22] A. Bürkle. DNA repair and PARP in aging , 2006, Free radical research.
[23] C. Pagès,et al. Unraveling a role for dopamine in Huntington's disease: the dual role of reactive oxygen species and D2 receptor stimulation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[24] T. Graf,et al. Early reversible induction of leukotriene synthesis in chicken myelomonocytic cells transformed by a temperature-sensitive mutant of avian leukemia virus E26. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[25] A. de Bruin,et al. Cloning and Characterization of Mouse E2F8, a Novel Mammalian E2F Family Member Capable of Blocking Cellular Proliferation* , 2005, Journal of Biological Chemistry.
[26] E. Matunis,et al. Regeneration of Male Germline Stem Cells by Spermatogonial Dedifferentiation in Vivo , 2004, Science.
[27] M. Hottiger,et al. Nuclear ADP-Ribosylation Reactions in Mammalian Cells: Where Are We Today and Where Are We Going? , 2006, Microbiology and Molecular Biology Reviews.
[28] J. Campisi,et al. Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation , 2004, Journal of Cell Science.
[29] T. Weinert,et al. Toward maintaining the genome: DNA damage and replication checkpoints. , 2002, Annual review of genetics.
[30] J. Lis,et al. PARP Goes Transcription , 2003, Cell.
[31] D. Toczyski,et al. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. , 2001, Genes & development.
[32] O. Ullrich,et al. Proteasome activation by poly-ADP-ribose-polymerase in human myelomonocytic cells after oxidative stress. , 2000, Free radical biology & medicine.
[33] C. Cass,et al. Biophysical characterization of human XRCC1 and its binding to damaged and undamaged DNA. , 2004, Biochemistry.
[34] K. Khanna,et al. Chk2 Activation Dependence on Nbs1 after DNA Damage , 2001, Molecular and Cellular Biology.
[35] A. Holmgren. Thioredoxin and glutaredoxin systems , 1989 .
[36] J. Enghild,et al. Extracellular superoxide dismutase protects against matrix degradation of heparan sulfate in the lung. , 2008, Antioxidants & redox signaling.
[37] D. Butterfield,et al. Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer’s disease brain contribute to neuronal death , 2002, Neurobiology of Aging.
[38] K. Pong. Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics , 2003, Expert opinion on biological therapy.
[39] A. Brenner,et al. Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation , 1998, Oncogene.
[40] P. Yaswen,et al. Loss of p53 function accelerates acquisition of telomerase activity in indefinite lifespan human mammary epithelial cell lines , 2003, Oncogene.
[41] R. Hass. Retrodifferentiation--an alternative biological pathway in human leukemia cells. , 1992, European journal of cell biology.
[42] J. Campisi,et al. Cancer and aging: a model for the cancer promoting effects of the aging stroma. , 2002, The international journal of biochemistry & cell biology.
[43] T. Oury,et al. Extracellular superoxide dismutase in pulmonary fibrosis. , 2008, Antioxidants & redox signaling.
[44] H. Gendelman,et al. Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[45] A. Lomri,et al. Reactive oxygen species and superoxide dismutases: role in joint diseases. , 2007, Joint, bone, spine : revue du rhumatisme.
[46] T. Lange,et al. Shelterin: the protein complex that shapes and safeguards human telomeres , 2005 .
[47] J. Shay,et al. Toward a molecular understanding of human breast cancer: A hypothesis , 2004, Breast Cancer Research and Treatment.
[48] C. Szabó,et al. The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors , 2002, Pharmacological Reviews.
[49] Jinshui Fan,et al. XRCC1 co-localizes and physically interacts with PCNA. , 2004, Nucleic acids research.
[50] G. Peters,et al. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence , 1996, Molecular and cellular biology.
[51] S. Lowe,et al. Tumor suppression by Ink4a-Arf: progress and puzzles. , 2003, Current opinion in genetics & development.
[52] M. Freedman,et al. Increased Peroxidation and Reduced Antioxidant Enzyme Activity in Alzheimer's Disease , 1998, Experimental Neurology.
[53] Lynda Chin,et al. E.: “A Summary of , 1968 .
[54] C. Maier,et al. Book Review: Role of Superoxide Dismutases in Oxidative Damage and Neurodegenerative Disorders , 2002 .
[55] H. Kaneto,et al. Role of Oxidative Stress in Pancreatic β‐Cell Dysfunction , 2004 .
[56] Kunihiro Matsumoto,et al. Recruitment of Mec1 and Ddc1 Checkpoint Proteins to Double-Strand Breaks Through Distinct Mechanisms , 2001, Science.
[57] J. Campisi. Cellular senescence and apoptosis: how cellular responses might influence aging phenotypes , 2003, Experimental Gerontology.
[58] W. Oertel,et al. Glia Protects Neurons against Extracellular Human Neuromelanin , 2007, Neurodegenerative Diseases.
[59] R. Hass. Retrodifferentiation and cell death. , 1994, Critical reviews in oncogenesis.
[60] J. Slack. Metaplasia and transdifferentiation: from pure biology to the clinic , 2007, Nature Reviews Molecular Cell Biology.
[61] P. Maher. The effects of stress and aging on glutathione metabolism , 2005, Ageing Research Reviews.
[62] J. Troncoso,et al. S-Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function , 2004, Science.
[63] F. Bonomini,et al. Atherosclerosis and oxidative stress. , 2008, Histology and histopathology.
[64] Samuel H. Wilson,et al. Direct Interaction between Mammalian DNA Polymerase β and Proliferating Cell Nuclear Antigen* , 2002, The Journal of Biological Chemistry.
[65] Hanh T. Nguyen,et al. Reversibility of muscle differentiation in the absence of commitment: Analysis of a myogenic cell line temperature-sensitive for commitment , 1983, Cell.
[66] Y. Matsumoto,et al. Molecular mechanism of PCNA-dependent base excision repair. , 2001, Progress in nucleic acid research and molecular biology.
[67] G. Maga,et al. Human Proliferating Cell Nuclear Antigen, Poly(ADP-ribose) Polymerase-1, and p21waf1/cip1 , 2003, Journal of Biological Chemistry.
[68] High dose antioxidant supplementation to MS patients , 1990, Biological Trace Element Research.
[69] A. Spradling,et al. Chromatin Loosening by Poly(ADP)-Ribose Polymerase (PARP) at Drosophila Puff Loci , 2003, Science.
[70] J. Campisi,et al. Secretion of Vascular Endothelial Growth Factor by Primary Human Fibroblasts at Senescence* , 2006, Journal of Biological Chemistry.
[71] L. Haupt,et al. Loss of Chromosomal Integrity in Human Mammary Epithelial Cells Subsequent to Escape from Senescence , 2001, Journal of mammary gland biology and neoplasia.
[72] C. Harley,et al. Telomeres shorten during ageing of human fibroblasts , 1990, Nature.
[73] In-kyu Lee,et al. The modulating effects of the overexpression of uncoupling protein 2 on the formation of reactive oxygen species in vascular cells. , 2007, Diabetes research and clinical practice.
[74] O. Ullrich,et al. Retrodifferentiation and rejuvenation of senescent monocytic cells requires PARP-1 , 2007, Experimental Gerontology.
[75] J. Stamler,et al. NO/redox disequilibrium in the failing heart and cardiovascular system. , 2005, The Journal of clinical investigation.
[76] Thomas B. L. Kirkwood,et al. Stress, DNA damage and ageing — an integrative approach , 2001, Experimental Gerontology.
[77] M. Kastan,et al. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation , 2003, Nature.
[78] K. Hasan,et al. Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease , 2006, Clinical Neuroscience Research.
[79] D. Kufe,et al. Phorbol Ester-induced Generation of Reactive Oxygen Species Is Protein Kinase Cβ-dependent and Required for SAPK Activation* , 2000, The Journal of Biological Chemistry.
[80] J. Lambeth. Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. , 2007, Free radical biology & medicine.
[81] Thea D. Tlsty,et al. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes , 2001, Nature.
[82] T. Tlsty,et al. Inactivation of p53 Function in Cultured Human Mammary Epithelial Cells Turns the Telomere-Length Dependent Senescence Barrier from Agonescence into Crisis , 2007, Cell cycle.
[83] S. Pieczenik,et al. Mitochondrial dysfunction and molecular pathways of disease. , 2007, Experimental and molecular pathology.
[84] Junjie Chen,et al. p53 Binding Protein 53BP1 Is Required for DNA Damage Responses and Tumor Suppression in Mice , 2003, Molecular and Cellular Biology.
[85] E. Blackburn,et al. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis , 1989, Nature.
[86] D. Rubinsztein,et al. Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin. , 2002, Human molecular genetics.
[87] P. Dollé,et al. Poly(ADP-ribose) Polymerase-2 (PARP-2) Is Required for Efficient Base Excision DNA Repair in Association with PARP-1 and XRCC1* , 2002, The Journal of Biological Chemistry.
[88] Qin M. Chen,et al. Measurements of hydrogen peroxide induced premature senescence:senescence-associated β-galactosidase and DNA synthesis index in human diploid fibroblasts with down-regulated p53 or Rb , 2004, Biogerontology.
[89] M. Smith,et al. Causes of oxidative stress in Alzheimer disease , 2007, Cellular and Molecular Life Sciences.
[90] O. Ullrich,et al. Regulation of the nuclear proteasome activity in myelomonocytic human leukemia cells after adriamycin treatment. , 2001, Blood.
[91] John M Sedivy,et al. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). , 2004, Molecular cell.
[92] R. Bonner,et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks , 2003, Nature Cell Biology.
[93] J. Keski‐Oja,et al. Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species. , 2008, Antioxidants & redox signaling.
[94] R. Abraham. Cell cycle checkpoint signaling through the ATM and ATR kinases. , 2001, Genes & development.
[95] D. Butterfield,et al. Redox regulation of cellular stress response in neurodegenerative disorders. , 2006, The Italian journal of biochemistry.
[96] Ji-Hoon Lee,et al. Direct Activation of the ATM Protein Kinase by the Mre11/Rad50/Nbs1 Complex , 2004, Science.
[97] John A. Murphy,et al. Reactions of oxyl radicals with DNA. , 1995, Free radical biology & medicine.
[98] B. Troen,et al. The biology of aging. , 2003, The Mount Sinai journal of medicine, New York.
[99] S. Croul,et al. Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis , 2000, Journal of the Neurological Sciences.
[100] C. Franceschi,et al. Aging, Longevity, Inflammation, and Cancer , 2004, Annals of the New York Academy of Sciences.
[101] N. Carter,et al. A DNA damage checkpoint response in telomere-initiated senescence , 2003, Nature.
[102] V. Víctor,et al. Targeting antioxidants to mitochondria: a potential new therapeutic strategy for cardiovascular diseases. , 2007, Current pharmaceutical design.
[103] R. Reddel. The role of senescence and immortalization in carcinogenesis. , 2000, Carcinogenesis.
[104] Dean P. Jones,et al. Extracellular redox state: refining the definition of oxidative stress in aging. , 2006, Rejuvenation research.
[105] R. Wiesner,et al. Mitochondrial DNA damage and the aging process–facts and imaginations , 2006, Free radical research.
[106] M. Newton,et al. Overcoming cellular senescence in human cancer pathogenesis. , 1998, Genes & development.
[107] B. Day. Antioxidants as potential therapeutics for lung fibrosis. , 2008, Antioxidants & redox signaling.
[108] C. Rinehart,et al. Aging and cancer: The role of stromal interactions with epithelial cells , 1997, Molecular carcinogenesis.
[109] I. Esaulenko,et al. Oxidant stress in the pathogenesis of multiple sclerosis , 2007, Neuroscience and Behavioral Physiology.
[110] G. Hannon,et al. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[111] Louis H Philipson,et al. Oxidative Reactive Species in Cell Injury: Mechanisms in Diabetes Mellitus and Therapeutic Approaches , 2005, Annals of the New York Academy of Sciences.
[112] A. Yasui,et al. Spatial and Temporal Cellular Responses to Single-Strand Breaks in Human Cells , 2003, Molecular and Cellular Biology.
[113] D. Kufe,et al. Internucleosomal DNA fragmentation during phorbol ester-induced monocytic differentiation and G0/G1 arrest. , 1992, The Journal of clinical investigation.
[114] T. Jacks,et al. Restoration of p53 function leads to tumour regression in vivo , 2007, Nature.
[115] E. Appella,et al. Chk2‐deficient mice exhibit radioresistance and defective p53‐mediated transcription , 2002, The EMBO journal.
[116] J. C. Romero,et al. Role of oxidative stress in angiotensin-induced hypertension. , 2003, American journal of physiology. Regulatory, integrative and comparative physiology.
[117] T. Lindahl,et al. Second pathway for completion of human DNA base excision‐repair: reconstitution with purified proteins and requirement for DNase IV (FEN1) , 1997, The EMBO journal.
[118] E. Kun,et al. Coenzymatic Activity of Randomly Broken or Intact Double-stranded DNAs in Auto and Histone H1 Trans-poly(ADP-ribosylation), Catalyzed by Poly(ADP-ribose) Polymerase (PARP I)* , 2002, The Journal of Biological Chemistry.
[119] T. Oury,et al. Extracellular superoxide dismutase in biology and medicine. , 2003, Free radical biology & medicine.
[120] P. Mander,et al. Microglia Proliferation Is Regulated by Hydrogen Peroxide from NADPH Oxidase1 , 2006, The Journal of Immunology.
[121] S. Elledge,et al. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases , 1993, Cell.
[122] R. Verdun,et al. Functional human telomeres are recognized as DNA damage in G2 of the cell cycle. , 2005, Molecular cell.
[123] M. Philbert,et al. Distribution of glutathione and glutathione-related enzyme systems in mitochondria and cytosol of cultured cerebellar astrocytes and granule cells , 1995, Brain Research.
[124] A. Giaccia,et al. The complexity of p53 modulation: emerging patterns from divergent signals. , 1998, Genes & development.