A brain serine/threonine protein kinase activated by Cdc42 and Rac1

[1]  P. Warne,et al.  Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro , 1993, Nature.

[2]  S. Elledge,et al.  Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1 , 1993, Nature.

[3]  Jonathan A. Cooper,et al.  Mammalian Ras interacts directly with the serine/threonine kinase raf , 1993, Cell.

[4]  M. Weber,et al.  Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase. , 1993, Science.

[5]  L. Lim,et al.  A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42 , 1993, Nature.

[6]  K. Kaibuchi,et al.  Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin , 1993, Molecular and cellular biology.

[7]  B. Errede,et al.  A conserved kinase cascade for MAP kinase activation in yeast. , 1993, Current opinion in cell biology.

[8]  H. Shuntoh,et al.  Autoactivation of catalytic (C alpha) subunit of cyclic AMP-dependent protein kinase by phosphorylation of threonine 197 , 1993, Molecular and cellular biology.

[9]  A. Hall,et al.  Different structural organization of Ras and Rho effector domains. , 1993, Oncogene.

[10]  L. Lim,et al.  Germ cell beta-chimaerin, a new GTPase-activating protein for p21rac, is specifically expressed during the acrosomal assembly stage in rat testis. , 1993, The Journal of biological chemistry.

[11]  K. Kaibuchi,et al.  A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[12]  R. W. Davis,et al.  A dominant truncation allele identifies a gene, STE20, that encodes a putative protein kinase necessary for mating in Saccharomyces cerevisiae. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[13]  A. Levitzki,et al.  Phosphorylation of the S. cerevisiae Cdc25 in response to glucose results in its dissociation from Ras , 1992, Nature.

[14]  T. M. Roberts.  A signal chain of events , 1992, Nature.

[15]  E. Krebs,et al.  The mitogen-activated protein kinase activator. , 1992, Current opinion in cell biology.

[16]  M. Whiteway,et al.  The protein kinase homologue Ste20p is required to link the yeast pheromone response G‐protein beta gamma subunits to downstream signalling components. , 1992, The EMBO journal.

[17]  T. Kataoka,et al.  The 70-kilodalton adenylyl cyclase-associated protein is not essential for interaction of Saccharomyces cerevisiae adenylyl cyclase with RAS proteins , 1992, Molecular and cellular biology.

[18]  O. Witte,et al.  A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. , 1992, Science.

[19]  M. Pazin,et al.  Triggering signaling cascades by receptor tyrosine kinases. , 1992, Trends in biochemical sciences.

[20]  R. Weinberg,et al.  Association between GTPase activators for Rho and Ras families , 1992, Nature.

[21]  C. Wollheim,et al.  The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins. , 1992, The Journal of biological chemistry.

[22]  P. Sluijs,et al.  The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway , 1992, Cell.

[23]  Kai Simons,et al.  The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway , 1992, Cell.

[24]  E. Hertzberg,et al.  Low molecular weight GTP-binding proteins in cardiac muscle. Association with a 32-kDa component related to connexins. , 1992, The Journal of biological chemistry.

[25]  C. Hall,et al.  Diversity and versatility of GTPase activating proteins for the p21rho subfamily of ras G proteins detected by a novel overlay assay. , 1992, Journal of Biological Chemistry.

[26]  Anne J. Ridley,et al.  The small GTP-binding protein rac regulates growth factor-induced membrane ruffling , 1992, Cell.

[27]  Anne J. Ridley,et al.  The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.

[28]  S. Vincent,et al.  Growth-regulated expression of rhoG, a new member of the ras homolog gene family , 1992, Molecular and cellular biology.

[29]  J. Parsons,et al.  pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[30]  P. Casey,et al.  Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties. , 1992, European journal of biochemistry.

[31]  A. Hall,et al.  Signal transduction through small GTPases—A tale of two GAPs , 1992, Cell.

[32]  A. Brown,et al.  GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents. , 1992, Science.

[33]  G. Bokoch,et al.  Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2. , 1991, Science.

[34]  S. Aaronson,et al.  Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product , 1991, Nature.

[35]  J. Woodgett,et al.  Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini , 1991, Molecular and cellular biology.

[36]  K. Kaibuchi,et al.  A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[37]  C. Hall,et al.  Bcr encodes a GTPase-activating protein for p21rac , 1991, Nature.

[38]  J. Shabanowitz,et al.  Identification of the regulatory phosphorylation sites in pp42/mitogen‐activated protein kinase (MAP kinase). , 1991, The EMBO journal.

[39]  F. McCormick,et al.  Regulators and effectors of ras proteins. , 1991, Annual review of cell biology.

[40]  I. Herskowitz,et al.  Signal transduction during pheromone response in yeast. , 1991, Annual review of cell biology.

[41]  A. Ullrich,et al.  Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42 , 1990, Molecular and cellular biology.

[42]  A. Hall,et al.  The cellular functions of small GTP-binding proteins. , 1990, Science.

[43]  W. Kabsch,et al.  Refined crystal structure of the triphosphate conformation of H‐ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis. , 1990, The EMBO journal.

[44]  J. Pringle,et al.  Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity , 1990, The Journal of cell biology.

[45]  J. Ferrell,et al.  Identification of a 42-kilodalton phosphotyrosyl protein as a serine(threonine) protein kinase by renaturation , 1990, Molecular and cellular biology.

[46]  A. Hall,et al.  Inhibition by phospholipids of the interaction between R-ras, rho, and their GTPase-activating proteins , 1989, Molecular and cellular biology.

[47]  G M Bokoch,et al.  rac, a novel ras-related family of proteins that are botulinum toxin substrates. , 1989, The Journal of biological chemistry.

[48]  A. Hall,et al.  Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins. , 1989, The Journal of biological chemistry.