Thyroid hormone (T3)-modification of polyethyleneglycol (PEG)-polyethyleneimine (PEI) graft copolymers for improved gene delivery to hepatocytes.
暂无分享,去创建一个
J. Rosenecker | C. Rudolph | A. Thünemann | C. Plank | U. Schillinger | Nathalie Sieverling | E. Lesina | H. Schönberger
[1] J. Rosenecker,et al. Interaction of polyamine gene vectors with RNA leads to the dissociation of plasmid DNA‐carrier complexes , 2006, The journal of gene medicine.
[2] K. Millen,et al. Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice. , 2006, Endocrinology.
[3] J. Rosenecker,et al. Uronic acids functionalized polyethyleneimine (PEI)-polyethyleneglycol (PEG)-graft-copolymers as novel synthetic gene carriers. , 2006, Biomaterials.
[4] Jaroslav Pelisek,et al. Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.
[5] N. Ferry,et al. Liver gene therapy: advances and hurdles , 2004, Gene therapy.
[6] D. Fischer,et al. Effect of poly(ethylene imine) molecular weight and pegylation on organ distribution and pharmacokinetics of polyplexes with oligodeoxynucleotides in mice. , 2004, Drug metabolism and disposition: the biological fate of chemicals.
[7] J. Behr,et al. A model for non‐viral gene delivery: through syndecan adhesion molecules and powered by actin , 2004, The journal of gene medicine.
[8] A. Johansson,et al. Non-viral delivery of the porphobilinogen deaminase cDNA into a mouse model of acute intermittent porphyria. , 2004, Molecular genetics and metabolism.
[9] C. Densmore,et al. Biodistribution and pharmacokinetics of aerosol and intravenously administered DNA-polyethyleneimine complexes: optimization of pulmonary delivery and retention. , 2003, Molecular therapy : the journal of the American Society of Gene Therapy.
[10] S S Gambhir,et al. Optical imaging of transferrin targeted PEI/DNA complexes in living subjects , 2003, Gene Therapy.
[11] R. Müller,et al. Oligomers of the Arginine-rich Motif of the HIV-1 TAT Protein Are Capable of Transferring Plasmid DNA into Cells* 210 , 2003, The Journal of Biological Chemistry.
[12] G. De Rosa,et al. Spectrophotometric determination of polyethylenimine in the presence of an oligonucleotide for the characterization of controlled release formulations. , 2003, Journal of pharmaceutical and biomedical analysis.
[13] S. Kawakami,et al. Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. , 2003, Molecular therapy : the journal of the American Society of Gene Therapy.
[14] E. Wagner,et al. Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice , 2002, Hepatology.
[15] R. Müller,et al. Nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine. , 2002, Biochimica et biophysica acta.
[16] E. Wagner,et al. Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity , 2002, Cancer Gene Therapy.
[17] Clive J Roberts,et al. Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. , 2002, Bioconjugate chemistry.
[18] D. Fischer,et al. The Structure of PEG-Modified Poly(Ethylene Imines) Influences Biodistribution and Pharmacokinetics of Their Complexes with NF-κB Decoy in Mice , 2002, Pharmaceutical Research.
[19] S. W. Kim,et al. A new synthesis of galactose-poly(ethylene glycol)-polyethylenimine for gene delivery to hepatocytes. , 2002, Journal of controlled release : official journal of the Controlled Release Society.
[20] E. Wagner,et al. Design and gene delivery activity of modified polyethylenimines. , 2001, Advanced drug delivery reviews.
[21] T. Visser,et al. Plasma membrane transport of thyroid hormones and its role in thyroid hormone metabolism and bioavailability. , 2001, Endocrine reviews.
[22] S. Carotta,et al. Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo , 2001, The journal of gene medicine.
[23] D. Liu,et al. Hydrodynamics-based gene delivery. , 2001, Current opinion in molecular therapeutics.
[24] H. Cölfen,et al. Synthesis of double-hydrophilic block copolymers with hydrophobic moieties for the controlled crystallization of minerals. , 2001 .
[25] G. Levi,et al. Rapid crossing of the pulmonary endothelial barrier by polyethylenimine/DNA complexes , 2000, Gene Therapy.
[26] J. Behr,et al. Systemic linear polyethylenimine (L‐PEI)‐mediated gene delivery in the mouse , 2000, The journal of gene medicine.
[27] J. Wolff,et al. High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. , 1999, Human gene therapy.
[28] C. Steer,et al. Nucleotide Exchange in Genomic DNA of Rat Hepatocytes Using RNA/DNA Oligonucleotides , 1999, The Journal of Biological Chemistry.
[29] M. Ogris,et al. PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery , 1999, Gene Therapy.
[30] S. Cheng,et al. Hormone-induced Translocation of Thyroid Hormone Receptors in Living Cells Visualized Using a Receptor Green Fluorescent Protein Chimera* , 1998, The Journal of Biological Chemistry.
[31] J. Behr,et al. In vitro gene delivery to hepatocytes with galactosylated polyethylenimine. , 1997, Bioconjugate chemistry.
[32] E. Krenning,et al. Transport of 3,5,3'-triiodothyronine into the perfused rat liver and subsequent metabolism are inhibited by fasting. , 1992, Endocrinology.
[33] A. Pontecorvi,et al. Differential effect of a new thyromimetic on triiodothyronine transport into myoblasts and hepatoma and neuroblastoma cells. , 1992, Biochimica et biophysica acta.
[34] I. Pastan,et al. Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts. , 1980, Proceedings of the National Academy of Sciences of the United States of America.
[35] I. Pastan,et al. Fluorescent rhodamine‐labeled thyroid hormone derivatives , 1979, FEBS letters.
[36] E. Wagner,et al. Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application , 2001, Gene Therapy.
[37] S. Ricard-Blum,et al. Kinetics of internalization and subcellular binding sites for T3 in mouse liver , 1996, Biology of the cell.
[38] E. Krenning,et al. Uptake and metabolism of 3,5,3'-triiodothyronine and 3,3',5'-triiodothyronine by human liver-derived cells: HepG2 cells as a model for thyroid hormone handling by human liver. , 1996, The Journal of clinical endocrinology and metabolism.
[39] Smoryzanova Oa,et al. Distribution kinetics and metabolism of triiodothyronine and thyroxine in the organs and tissues of mice with transplanted Lewis carcinoma , 1985 .