Aqueous and hydro-alcoholic extracts of Echinacea purpurea (L) Moench as traditional herbal remedies with immunotropic activity

Correspondence: Ewa Skopinska-Ro?ewska, Department of Pathology, Biostructure Center, Medical University of Warsaw, Cha3ubinskiego 5, 02-004 Warsaw, Poland. Phone number: +48 600 47 94 95, Email: ewaskop@hotmail.com Echinacea purpurea preparations are derived from the aerial parts of purple coneflower, Echinacea purpurea (L) Moench Asteraceae=Compositae, which grows throughout North America and Europe. Information about use of Echinacea first came from American Indians. They used leaves and roots/rhizomes of Echinacea purpurea, Echinacea angustifolia DC and Echinacea pallida Nutt, internally and externally, as remedies for many ailments. Plants were used fresh or, most often, dried, as infusion, succus or decoction [1-6]. The most ancient form of medical herbs use , aside from consuming the fresh or dried plant, is aqueous extract which may be dried to form powder. According to Materia Medica [7] contemporary “Echinacea purpurea preparations include liquid(aqueous or hydro-alcoholic)extracts of fresh or dried whole plant or aerial parts; fresh or dried preparations of Review paper

[1]  D. Moerman Native American herbal prescription sticks , 2008 .

[2]  R. Bauer,et al.  Echinacea for preventing and treating the common cold. , 2008, Planta medica.

[3]  R. Bauer,et al.  The Role of Alkamides as an Active Principle of Echinacea , 2007, Planta medica.

[4]  F. Chaves,et al.  Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response. , 2003, Revista de biologia tropical.

[5]  A. Meyer,et al.  Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins. , 2005, Journal of agricultural and food chemistry.

[6]  R. Rychlik,et al.  Nutzenbewertung der Therapie chronisch rezidivierender Atemwegsinfekte mit Echinacin , 2005 .

[7]  J. Hudson,et al.  Echinacea purpurea. Aerial Parts Contain Multiple Antiviral Compounds , 2005 .

[8]  R. Rychlik,et al.  [Effectiveness of echinacin in therapy of chronic recurrent respiratory disease]. , 2005, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)).

[9]  S. Yale,et al.  Echinacea purpurea therapy for the treatment of the common cold: a randomized, double-blind, placebo-controlled clinical trial. , 2004, Archives of internal medicine.

[10]  U. Demkow,et al.  The in vivo effect of Echinacea purpurea succus on various functions of human blood leukocytes , 2004 .

[11]  S. Moreno,et al.  Assessment of the Biological Effects of a Natural Extract of Equinacea Purpurea: An In Vitro Analysis , 2004 .

[12]  E. Skopińska-Różewska,et al.  Experimental immunology The effect of Centella asiatica, Echinacea purpurea and Melaleuca alternifolia on cellular immunity in mice , 2003 .

[13]  K. Hostettmann Geschichte einer Pflanze am Beispiel von Echinacea , 2003, Complementary Medicine Research.

[14]  K. Hostettmann [History of a plant: the example of Echinacea]. , 2003, Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine.

[15]  D. Freier,et al.  Enhancement of the Humoral Immune Response by Echinacea purpurea in Female Swiss Mice , 2003, Immunopharmacology and immunotoxicology.

[16]  E. Skopińska-Różewska,et al.  Echinacea purpurea stimulates cellular immunity and anti-bacterial defence independently of the strain of mice. , 2003, Polish journal of veterinary sciences.

[17]  E. Skopińska-Różewska,et al.  The effect of herbal remedy on the development of Trichinella spiralis infection in mice. , 2003, Polish journal of veterinary sciences.

[18]  K. Bone Echinacea: What Makes It Work? , 2002 .

[19]  M. Schäfer,et al.  Efficacy of Echinacea purpurea in Patients with a Common Cold , 2001, Arzneimittelforschung.

[20]  J. Barnes Principles and practice of phytotherapy modern herbal medicine , 2001 .

[21]  T. Durance,et al.  Retention of caffeic acid derivatives in dried Echinacea purpurea. , 2000, Journal of agricultural and food chemistry.

[22]  T. Durance,et al.  Retention of alkamides in dried Echinacea purpurea. , 2000, Journal of agricultural and food chemistry.

[23]  G. F. Lindenmuth,et al.  The efficacy of echinacea compound herbal tea preparation on the severity and duration of upper respiratory and flu symptoms: a randomized, double-blind placebo-controlled study. , 2000, Journal of alternative and complementary medicine.

[24]  R. Bauer,et al.  Echinacea for preventing and treating the common cold. , 2000, The Cochrane database of systematic reviews.

[25]  Daniel E. Moerman,et al.  Native American Ethnobotany , 1998 .

[26]  N. Beuscher,et al.  Studies on Antigen Specifity of Immunoreactive Arabinogalactan Proteins Extracted from Baptisia tinctoria and Echinacea purpurea , 1992, Planta medica.

[27]  A. Wacker,et al.  [Virus-inhibition by echinacea purpurea (author's transl)]. , 1978, Planta medica.