Early warning of some notifiable infectious diseases in China by the artificial neural network

In order to accurately grasp the timing for the prevention and control of diseases, we established an artificial neural network model to issue early warning signals. The real-time recurrent learning (RTRL) and extended Kalman filter (EKF) methods were performed to analyse four types of respiratory infectious diseases and four types of digestive tract infectious diseases in China to comprehensively determine the epidemic intensities and whether to issue early warning signals. The numbers of new confirmed cases per month between January 2004 and December 2017 were used as the training set; the data from 2018 were used as the test set. The results of RTRL showed that the number of new confirmed cases of respiratory infectious diseases in September 2018 increased abnormally. The results of the EKF showed that the number of new confirmed cases of respiratory infectious diseases increased abnormally in January and February of 2018. The results of these two algorithms showed that the number of new confirmed cases of digestive tract infectious diseases in the test set did not have any abnormal increases. The neural network and machine learning can further enrich and develop the early warning theory.

[1]  Biao Xu,et al.  Establishing a web-based integrated surveillance system for early detection of infectious disease epidemic in rural China: a field experimental study , 2012, BMC Medical Informatics and Decision Making.

[2]  Scott M. Pappada,et al.  Neural network-based real-time prediction of glucose in patients with insulin-dependent diabetes. , 2011, Diabetes technology & therapeutics.

[3]  Dan Liu,et al.  Modeling seasonal measles transmission in China , 2015, Commun. Nonlinear Sci. Numer. Simul..

[4]  Dawei Guan,et al.  The epidemiological characteristics and genetic diversity of dengue virus during the third largest historical outbreak of dengue in Guangdong, China, in 2014. , 2016, The Journal of infection.

[5]  H. Robbins A Stochastic Approximation Method , 1951 .

[6]  Donald C. Wunsch,et al.  Recurrent neural network based prediction of epileptic seizures in intra- and extracranial EEG , 2000, Neurocomputing.

[7]  Virginia E. Pitzer,et al.  Seasonal dynamics of typhoid and paratyphoid fever , 2018, Scientific Reports.

[8]  Simon Haykin,et al.  Neural Networks and Learning Machines , 2010 .

[9]  R. F. Grais,et al.  Explaining Seasonal Fluctuations of Measles in Niger Using Nighttime Lights Imagery , 2011, Science.

[10]  Nancy Fullman,et al.  Global malaria mortality between 1980 and 2010: a systematic analysis , 2012, The Lancet.

[11]  Melissa Aczon,et al.  Dynamic Mortality Risk Predictions in Pediatric Critical Care Using Recurrent Neural Networks , 2017, ArXiv.

[12]  Jiming Liu,et al.  Inferring Plasmodium vivax Transmission Networks from Tempo-Spatial Surveillance Data , 2014, PLoS neglected tropical diseases.

[13]  John E. Moody,et al.  Towards Faster Stochastic Gradient Search , 1991, NIPS.

[14]  E. Mykhalovskiy,et al.  The Global Public Health Intelligence Network and Early Warning Outbreak Detection , 2006 .

[15]  Zhong-Jie Li,et al.  [Preliminary application on China Infectious Diseases Automated-alert and Response System (CIDARS), between 2008 and 2010]. , 2011, Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi.

[16]  Harold J. Kushner,et al.  wchastic. approximation methods for constrained and unconstrained systems , 1978 .

[17]  Mingxia Hu,et al.  Seasonal pattern of influenza activity in a subtropical city, China, 2010–2015 , 2017, Scientific Reports.

[18]  Ho-Jin Choi,et al.  Modeling long-term human activeness using recurrent neural networks for biometric data , 2017, BMC Medical Informatics and Decision Making.

[19]  Auda Fares,et al.  Seasonality of Hepatitis: A Review Update , 2015, Journal of family medicine and primary care.

[20]  Michael J. Ryan,et al.  The Global Outbreak Alert and Response Network , 2014, Global public health.

[21]  Feng-Feng Shao,et al.  High Mean Water Vapour Pressure Promotes the Transmission of Bacillary Dysentery , 2015, PloS one.