Lymph node metastases in early rectal cancer

Local excision of early rectal tumours is an attractive proposition, avoiding the morbidity and mortality of major resection and possible permanent stoma. This study was designed to investigate the incidence of lymph node metastases associated with tumours that are locally confined to the bowel wall. A total of 454 rectal excision specimens were reviewed. Twenty‐two (20 per cent) of 109 patients with tumours locally confined to the bowel wall had metastases in local lymph nodes, although 14 of these had only one or two involved nodes. Three of 27 patients with tumours that did not penetrate through the submucosa had lymph node metastases. Less well differentiated tumours were more likely to have metastasized but there was no significant difference in the height or size of tumours or in the depth of invasion between patients with or without lymph node metastases.

[1]  Dixon Ar,et al.  Carcinoma of the rectum: a 10-year experience. , 1991 .

[2]  A. Horn,et al.  Transanal extirpation for early rectal cancer , 1989, Diseases of the colon and rectum.

[3]  R. Thoeni,et al.  CT for the evaluation of carcinomas in the colon and rectum. , 1989, Seminars in ultrasound, CT, and MR.

[4]  J. Jass,et al.  Prognostic value of direct spread in Dukes' C cases of rectal cancer , 1989, Diseases of the colon and rectum.

[5]  J. Virjee,et al.  Preoperative assessment of mesorectal lymph node involvement in rectal cancer , 1989, The British journal of surgery.

[6]  K. Bland,et al.  What's New In General Surgery. Sphincter‐Saving Procedures for Distal Carcinoma of the Rectum , 1989, Annals of surgery.

[7]  R. Heald,et al.  RECURRENCE AND SURVIVAL AFTER TOTAL MESORECTAL EXCISION FOR RECTAL CANCER , 1986, The Lancet.

[8]  S. Cawthorn,et al.  Clearance technique for the detection of lymph nodes in colorectal cancer , 1986, The British journal of surgery.

[9]  B. Fisher,et al.  The relationship of depth of penetration and tumor size to the number of positive nodes in dukes C colorectal cancer , 1984, Cancer.

[10]  A. Dixon,et al.  The clinical staging of rectal cancer , 1982, The British journal of surgery.

[11]  M. R. Lock,et al.  The treatment of early colorectal cancer by local excision , 1978, The British journal of surgery.

[12]  H. Bussey,et al.  Policy of local excision for early cancer of the colorectum. , 1977, Gut.

[13]  Mason Ay.  Role of local surgery in carcinoma of the rectum. , 1976 .

[14]  R. Jones,et al.  Prognostic factors in carcinoma of the colon and rectum. , 1968, American journal of surgery.

[15]  L. Ackerman,et al.  Small primary adenocarcinomas of the colon and rectum. , 1962, JAMA.

[16]  F. A. Coller,et al.  THE PROGNOSTIC SIGNIFICANCE OF DIRECT EXTENSION OF CARCINOMA OF THE COLON AND RECTUM , 1954, Annals of surgery.