A federated DBMS-based integrated environment for molecular biology

Interest in database support for scientific information management has been considerably growing in the recent past. We look into one specific scientific area, i.e. molecular biology. The analysis of the current molecular biology working environment consisting of various independent software components shows several shortcomings and thus leads to requirements for an integrated working environment. We propose an architecture for an integrated system, the centre of which is a federated database system, the data repository. Its main benefits are a central data administration, a uniform data representation, the possibility of data reuse, and ad hoc query facilities. In addition, new application tools can be implemented on top of the repository easily and thus much faster than today.<<ETX>>

[1]  Jessie B. Kennedy,et al.  Modelling Ecological Data , 1992, SSDBM.

[2]  Victor M. Markowitz,et al.  Data Management for Genomic Mapping Applications: A Case Study , 1992, SSDBM.

[3]  David J. DeWitt,et al.  The Object-Oriented Database System Manifesto , 1994, Building an Object-Oriented Database System, The Story of O2.

[4]  John L. Pfaltz,et al.  Summary of the final report of the NSF workshop on scientific database management , 1990, SGMD.

[5]  G. H. Hamm,et al.  The EMBL data library , 1993, Nucleic Acids Res..

[6]  P. Pearson The genome data base (GDB)--a human gene mapping repository. , 1991, Nucleic acids research.

[7]  Changhwan Lee,et al.  Redesigning, implementing and integrating Escherichia coli genome software tools with an object-oriented database system , 1992, Comput. Appl. Biosci..

[8]  David Maier,et al.  Object-oriented Database Support for Computational Chemistry , 1992, SSDBM.

[9]  Harry K. T. Wong,et al.  Micro and macro statistical/scientific database management , 1984, 1984 IEEE First International Conference on Data Engineering.

[10]  Ali R. Hurson,et al.  A taxonomy and current issues in multidatabase systems , 1992, Computer.

[11]  Oliver Günther,et al.  Research issues in spatial databases , 1990, SGMD.

[12]  Carole A. Goble,et al.  A descriptive semantic formalism for medicine , 1993, Proceedings of IEEE 9th International Conference on Data Engineering.

[13]  L T Hunt,et al.  The PIR protein sequence database. , 1991, Nucleic acids research.

[14]  Francis Jack Smith,et al.  Integration of Scientific Data and Formulae in an Object-Oriented System , 1992, SSDBM.

[15]  Arie Shoshani,et al.  Characteristics of Scientific Databases , 1984, VLDB.

[16]  Karen A. Frenkel,et al.  The human genome project and informatics , 1991, CACM.