Docetaxel plus oral metronomic cyclophosphamide: A phase II study with pharmacodynamic and pharmacogenetic analyses in castration‐resistant prostate cancer patients
暂无分享,去创建一个
G. Francia | R. Danesi | T. Di Desidero | P. Orlandi | G. Bocci | A. Fioravanti | A. Falcone | L. Derosa | A. Fontana | L. Galli | A. Antonuzzo | R. Marconcini | E. Biasco | A. Farnesi
[1] R. Gomis,et al. Cyclooxygenase‐2 inhibitor suppresses tumour progression of prostate cancer bone metastases in nude mice , 2014, BJU international.
[2] M. Picardo,et al. Functional and pharmacodynamic evaluation of metronomic cyclophosphamide and docetaxel regimen in castration-resistant prostate cancer. , 2013, Future oncology.
[3] G. Francia,et al. VEGF-A polymorphisms predict progression-free survival among advanced castration-resistant prostate cancer patients treated with metronomic cyclophosphamide , 2013, British Journal of Cancer.
[4] Thierry Gil,et al. Aflibercept versus placebo in combination with docetaxel and prednisone for treatment of men with metastatic castration-resistant prostate cancer (VENICE): a phase 3, double-blind randomised trial. , 2013, The Lancet. Oncology.
[5] S. Olgac,et al. Phase II trial of neoadjuvant docetaxel and CG1940/CG8711 followed by radical prostatectomy in patients with high-risk clinically localized prostate cancer. , 2013, The oncologist.
[6] M. Gleave,et al. Phase III, randomized, placebo-controlled study of docetaxel in combination with zibotentan in patients with metastatic castration-resistant prostate cancer. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[7] E. Yu,et al. Castrate-resistant prostate cancer: postdocetaxel management , 2013, Current opinion in urology.
[8] P. Paliwal,et al. Long-term use of dasatinib in patients with metastatic castration-resistant prostate cancer after receiving the combination of dasatinib and docetaxel , 2013, Cancer management and research.
[9] N. Clarke. Landmarks in non‐hormonal pharmacological therapies for castration‐resistant prostate cancer , 2012, BJU international.
[10] J. Burke,et al. Randomized phase II trial of docetaxel plus prednisone in combination with placebo or AT-101, an oral small molecule Bcl-2 family antagonist, as first-line therapy for metastatic castration-resistant prostate cancer. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.
[11] H. Mackay,et al. Vascular Endothelial Growth Factor Pathway Polymorphisms as Prognostic and Pharmacogenetic Factors in Cancer: A Systematic Review and Meta-analysis , 2012, Clinical Cancer Research.
[12] P. Kantoff,et al. Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[13] G. Bocci,et al. Cyclophosphamide-based metronomic chemotherapy: after 10 years of experience, where do we stand and where are we going? , 2012, Critical reviews in oncology/hematology.
[14] T. Nelius,et al. Oral/metronomic cyclophosphamide-based chemotherapy as option for patients with castration-refractory prostate cancer: review of the literature. , 2011, Cancer treatment reviews.
[15] P. Albers,et al. Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] R. Danesi,et al. Metronomic Chemotherapy for Metastatic Prostate Cancer , 2010, Drugs & aging.
[17] L. Landi,et al. METRONOMIC CYCLOPHOSPHAMIDE IN ELDERLY PATIENTS WITH ADVANCED, CASTRATION‐RESISTANT PROSTATE CANCER , 2010, Journal of the American Geriatrics Society.
[18] S. Steinberg,et al. Phase II trial of bevacizumab, thalidomide, docetaxel, and prednisone in patients with metastatic castration-resistant prostate cancer. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[19] A. Goldhirsch,et al. Predictive Potential of Angiogenic Growth Factors and Circulating Endothelial Cells in Breast Cancer Patients Receiving Metronomic Chemotherapy Plus Bevacizumab , 2009, Clinical Cancer Research.
[20] D. Venzon,et al. The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors , 2009, Molecular Cancer Therapeutics.
[21] L. Landi,et al. Clinical and Pharmacodynamic Evaluation of Metronomic Cyclophosphamide, Celecoxib, and Dexamethasone in Advanced Hormone-refractory Prostate Cancer , 2009, Clinical Cancer Research.
[22] R. Kerbel,et al. Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. , 2008, Cancer cell.
[23] S. Solomon,et al. Cardiovascular Risk of Celecoxib in 6 Randomized Placebo-Controlled Trials: The Cross Trial Safety Analysis , 2008, Circulation.
[24] I. Tannock,et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] C. Pfister,et al. Preliminary results of the Prostacox phase II trial in hormonal refractory prostate cancer , 2007, BJU international.
[26] R. Kerbel,et al. Pharmacodynamic and pharmacokinetic study of chronic low-dose metronomic cyclophosphamide therapy in mice , 2007, Molecular Cancer Therapeutics.
[27] M. Gross,et al. A phase II trial of docetaxel and erlotinib as first-line therapy for elderly patients with androgen-independent prostate cancer , 2007, BMC cancer.
[28] C. Tangen,et al. Evaluation of prostate-specific antigen declines for surrogacy in patients treated on SWOG 99-16. , 2006, Journal of the National Cancer Institute.
[29] S. Steinberg,et al. A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer. , 2006, Clinical cancer research : an official journal of the American Association for Cancer Research.
[30] R. Kerbel,et al. Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy. , 2005, Cancer research.
[31] Marc A Pfeffer,et al. Cardiovascular Risk Associated With Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention , 2005, The New England journal of medicine.
[32] C. Cordon-Cardo,et al. Celecoxib Inhibits Prostate Cancer Growth: Evidence of a Cyclooxygenase-2-Independent Mechanism , 2005, Clinical Cancer Research.
[33] Kristian Pietras,et al. A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[34] E. Maltezos,et al. VEGF gene sequence variation defines VEGF gene expression status and angiogenic activity in non-small cell lung cancer. , 2004, Lung cancer.
[35] C. Tangen,et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. , 2004, The New England journal of medicine.
[36] S. Steinberg,et al. Randomized phase II trial of docetaxel plus thalidomide in androgen-independent prostate cancer. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[37] R. Pruthi,et al. A pilot study of use of the cyclooxygenase‐2 inhibitor celecoxib in recurrent prostate cancer after definitive radiation therapy or radical prostatectomy , 2004, BJU international.
[38] W. Oh,et al. A Phase II study of estramustine, docetaxel, and carboplatin with granulocyte–colony‐stimulating factor support in patients with hormone‐refractory prostate carcinoma , 2003, Cancer.
[39] A. Barqawi,et al. Metronomic therapy with cyclophosphamide and dexamethasone for prostate carcinoma , 2003, Cancer.
[40] R. Kerbel,et al. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[41] R. Kerbel,et al. Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells. , 2003, Cancer research.
[42] M. Egorin,et al. Weekly high-dose calcitriol and docetaxel in metastatic androgen-independent prostate cancer. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[43] B. Teicher,et al. An in vitro tumor model: analysis of angiogenic factor expression after chemotherapy. , 2002, Cancer research.
[44] Peter Bohlen,et al. Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water. , 2002, Cancer research.
[45] R. Kerbel,et al. A role for survivin in chemoresistance of endothelial cells mediated by VEGF , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[46] J. Masferrer,et al. Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. , 2002, Cancer research.
[47] B. Freidlin,et al. Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[48] R. Danesi,et al. Vascular endothelial growth factor pharmacogenetics: a new perspective for anti-angiogenic therapy. , 2007, Pharmacogenomics.
[49] P. Carmeliet,et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death , 2003, Nature Genetics.