Volumetric Assessment of Breast Tissue Composition from FFDM Images

We present first results from a new automated algorithm for the volumetric measurement of the composition of breast tissue from digital mammograms. The new algorithm overcomes issues in previous implementations through better segmentation and use of additional information We measure the success of the new algorithm using an overall quality metric based upon the results from a large multi-site, multi-vendor, multi-detector set of digitally acquired mammograms.

[1]  Opper,et al.  HERITABILITY OF MAMMOGRAPHIC DENSITY, A RISK FACTOR FOR BREAST CANCER , 2002 .

[2]  Michael Brady,et al.  Evaluating the Effectiveness of Using Standard Mammogram Form to Predict Breast Cancer Risk: Case-Control Study , 2008, Cancer Epidemiology Biomarkers & Prevention.

[3]  Susan M. Astley,et al.  A New Step-Wedge for the Volumetric Measurement of Mammographic Density , 2006, Digital Mammography / IWDM.

[4]  D. Vanel The American College of Radiology (ACR) Breast Imaging and Reporting Data System (BI-RADS): a step towards a universal radiological language? , 2007, European journal of radiology.

[5]  R. Warren,et al.  Initial experiences of using an automated volumetric measure of breast density: the standard mammogram form. , 2006, The British journal of radiology.

[6]  M. Brady,et al.  Comparing measurements of breast density , 2007, Physics in medicine and biology.

[7]  Daniel B Kopans,et al.  Basic physics and doubts about relationship between mammographically determined tissue density and breast cancer risk. , 2008, Radiology.

[8]  Ralph Highnam,et al.  Comparison of a New and Existing Method of Mammographic Density Measurement: Intramethod Reliability and Associations with Known Risk Factors , 2007, Cancer Epidemiology Biomarkers & Prevention.

[9]  Nico Karssemeijer,et al.  Volumetric breast density estimation from full-field digital mammograms , 2006, IEEE Trans. Medical Imaging.

[10]  Michael Brady,et al.  Mammographic Image Analysis , 1999, Computational Imaging and Vision.

[11]  R. Warren,et al.  Breast density: agreement of measures from film and digital image. , 2003, The British journal of radiology.

[12]  Dan Rico,et al.  A volumetric method for estimation of breast density on digitized screen-film mammograms. , 2003, Medical physics.

[13]  J. Wolfe Breast patterns as an index of risk for developing breast cancer. , 1976, AJR. American journal of roentgenology.

[14]  George Davey Smith,et al.  Breast composition measurements using retrospective standard mammogram form (SMF) , 2006, Digital Mammography / IWDM.

[15]  Jennifer A Harvey,et al.  Quantitative assessment of mammographic breast density: relationship with breast cancer risk. , 2004, Radiology.

[16]  N. Boyd,et al.  The quantitative analysis of mammographic densities. , 1994, Physics in medicine and biology.