Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication.
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J. Prieto | I. Melero | J. Pérez-Gracia | I. Tirapu | E. Huarte | A. Arina | O. Murillo | S. Hervás-Stubbs | E. Larrea | J. Riezu-Boj | M. Civeira | C. Alfaro | R. Hernández-Alcoceba | A. Azpilicueta | S. Bortolanza | J. Prieto
[1] J. Curtsinger,et al. Signal 3 Tolerant CD8 T Cells Degranulate in Response to Antigen but Lack Granzyme B to Mediate Cytolysis1 , 2005, The Journal of Immunology.
[2] J. Sprent,et al. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection , 2005, The Journal of experimental medicine.
[3] K. Matsushima,et al. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs , 2005, The Journal of experimental medicine.
[4] C. Meijer,et al. Antigen Gene Transfer to Human Plasmacytoid Dendritic Cells Using Recombinant Adenovirus and Vaccinia Virus Vectors , 2005, Cellular oncology : the official journal of the International Society for Cellular Oncology.
[5] K. Conzelmann,et al. Viruses know it all: new insights into IFN networks. , 2005, Trends in immunology.
[6] J. Prieto,et al. Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.
[7] R. Schreiber,et al. A critical function for type I interferons in cancer immunoediting , 2005, Nature Immunology.
[8] Osamu Takeuchi,et al. Cell type-specific involvement of RIG-I in antiviral response. , 2005, Immunity.
[9] J. Barrio,et al. Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients. , 2005, Gastroenterology.
[10] A. Narbey. Update on viral hepatitis. , 2005, Nursing times.
[11] D. Larkin,et al. Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy. , 2005, Blood.
[12] L. Platanias. Mechanisms of type-I- and type-II-interferon-mediated signalling , 2005, Nature Reviews Immunology.
[13] Giovanna Lombardi,et al. Type I interferons and the innate immune response--more than just antiviral cytokines. , 2005, Molecular immunology.
[14] A. Lok,et al. Update on viral hepatitis in 2004 , 2005, Current opinion in gastroenterology.
[15] P. Darcy,et al. Gene modification strategies to induce tumor immunity. , 2005, Immunity.
[16] E. Fish,et al. Diversity and relatedness among the type I interferons. , 2004, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[17] G. Trinchieri,et al. Plasmacytoid dendritic cells in immunity , 2004, Nature Immunology.
[18] C. D. Krause,et al. Interferons, interferon‐like cytokines, and their receptors , 2004, Immunological reviews.
[19] J. Prieto,et al. IFN-α5 Mediates Stronger Tyk2-Stat-Dependent Activation and Higher Expression of 2′,5′-Oligoadenylate Synthetase Than IFN-α2 in Liver Cells , 2004 .
[20] C. Rinaldo,et al. Virus infection of dendritic cells: portal for host invasion and host defense. , 2004, Trends in microbiology.
[21] R. Hill,et al. E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models , 2003, Nature Biotechnology.
[22] J. Prieto,et al. Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses , 2003, Journal of Virology.
[23] N. Bhardwaj,et al. Type I interferons promote cross-priming: more functions for old cytokines , 2003, Nature Immunology.
[24] M. Magnusson,et al. The Maturation of Murine Dendritic Cells Induced by Human Adenovirus Is Mediated by the Fiber Knob Domain* , 2003, Journal of Biological Chemistry.
[25] P. Borrow,et al. Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon , 2003, Nature Immunology.
[26] Persephone Borrow,et al. Viral infection switches non-plasmacytoid dendritic cells into high interferon producers , 2003, Nature.
[27] J. Prieto,et al. Pancreatic cancer escape variants that evade immunogene therapy through loss of sensitivity to IFNγ-induced apoptosis , 2003, Gene Therapy.
[28] Y. Takakura,et al. Therapeutic effect of intravenous interferon gene delivery with naked plasmid DNA in murine metastasis models. , 2002, Molecular therapy : the journal of the American Society of Gene Therapy.
[29] R. DeMatteo,et al. Adenovirus infection enhances dendritic cell immunostimulatory properties and induces natural killer and T-cell-mediated tumor protection. , 2002, Cancer research.
[30] Michael G. Katze,et al. Viruses and interferon: a fight for supremacy , 2002, Nature Reviews Immunology.
[31] Molecular therapy , 2002, Journal of the Neurological Sciences.
[32] Yong‐jun Liu,et al. Mouse and human dendritic cell subtypes , 2002, Nature Reviews Immunology.
[33] T. Taniguchi,et al. The interferon-α/β system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors , 2002 .
[34] Marc Dalod,et al. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology , 2001, Nature Immunology.
[35] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[36] J. Prieto,et al. αvβ3 Integrin-Mediated Adenoviral Transfer of Interleukin-12 at the Periphery of Hepatic Colon Cancer Metastases Induces VCAM-1 Expression and T-Cell Recruitment , 2001 .
[37] F. Belardelli,et al. Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. , 2001, Immunity.
[38] J. Prieto,et al. Alpha(v)beta(3) integrin-mediated adenoviral transfer of interleukin-12 at the periphery of hepatic colon cancer metastases induces VCAM-1 expression and T-cell recruitment. , 2001, Molecular therapy : the journal of the American Society of Gene Therapy.
[39] C. Maliszewski,et al. Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures. , 2000, Blood.
[40] A. Thomson,et al. Recombinant Adenovirus Induces Maturation of Dendritic Cells via an NF-κB-Dependent Pathway , 2000, Journal of Virology.
[41] D. Levy,et al. Distinct Requirements for IFNs and STAT1 in NK Cell Function1 , 2000, The Journal of Immunology.
[42] L. Falo,et al. Intravenous injection of naked DNA encoding secreted flt3 ligand dramatically increases the number of dendritic cells and natural killer cells in vivo. , 2000, Human gene therapy.
[43] A. Enk,et al. Dendritic cell‐based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti‐melanoma immunity , 1999, The journal of gene medicine.
[44] J. Prieto,et al. Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas , 1999, Gene Therapy.
[45] P. Liljeström,et al. Two-Helper RNA System for Production of Recombinant Semliki Forest Virus Particles , 1999, Journal of Virology.
[46] R. Roberts,et al. The Evolution of the Type I Interferons1 , 1998 .
[47] R. Khan,et al. Update on Viral Hepatitis , 1997, Journal of the Royal College of Physicians of London.
[48] K. Anderson,et al. Adenovirus early region 1A modulation of interferon antiviral activity , 1987, Journal of virology.
[49] G. Trinchieri,et al. Production of type I interferons: plasmacytoid dendritic cells and beyond , 2005 .
[50] Yong‐jun Liu,et al. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. , 2005, Annual review of immunology.
[51] J. Prieto,et al. IFN-alpha5 mediates stronger Tyk2-stat-dependent activation and higher expression of 2',5'-oligoadenylate synthetase than IFN-alpha2 in liver cells. , 2004, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[52] T. Michiels,et al. Characterization of interferon-alpha 13, a novel constitutive murine interferon-alpha subtype. , 2003 .
[53] T. Taniguchi,et al. The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. , 2002, Current opinion in immunology.
[54] R. Alemany,et al. A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[55] C Caux,et al. Immunobiology of dendritic cells. , 2000, Annual review of immunology.
[56] R. Roberts,et al. The evolution of the type I interferons. , 1998, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[57] Thomas D. Schmittgen,et al. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method , 2022 .