Multilayered epithelium in a rat model and human Barrett's esophagus: Similar expression patterns of transcription factors and differentiation markers

[1]  B. Hogan,et al.  Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm , 2007, Development.

[2]  P. Hainaut,et al.  Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture. , 2007, American journal of physiology. Gastrointestinal and liver physiology.

[3]  Peng Wang,et al.  Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. , 2006, Carcinogenesis.

[4]  N. Nishioka,et al.  Multilayered Epithelium May Be Found in Patients With Barrett’s Epithelium and Dysplasia or Adenocarcinoma , 2006, Digestive Diseases and Sciences.

[5]  Jason S. Carroll,et al.  p63 regulates an adhesion programme and cell survival in epithelial cells , 2006, Nature Cell Biology.

[6]  D. Fitzpatrick,et al.  Mutations in SOX2 cause anophthalmia-esophageal-genital (AEG) syndrome. , 2006, Human molecular genetics.

[7]  D. Roop,et al.  P63 deficiency: a failure of lineage commitment or stem cell maintenance? , 2005, The journal of investigative dermatology. Symposium proceedings.

[8]  Y. Kadowaki,et al.  Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett’s epithelium , 2005, Gut.

[9]  T. Tsukamoto,et al.  Sox2 expression in human stomach adenocarcinomas with gastric and gastric‐and‐intestinal‐mixed phenotypes , 2005, Histopathology.

[10]  W. Bodmer,et al.  CDX1 is an important molecular mediator of Barrett's metaplasia. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[11]  N. Shaheen Advances in Barrett's esophagus and esophageal adenocarcinoma. , 2005, Gastroenterology.

[12]  R. Orlando Pathogenesis of reflux esophagitis and Barrett's esophagus. , 2005, The Medical clinics of North America.

[13]  P. Guillem How to Make a Barrett Esophagus: Pathophysiology of Columnar Metaplasia of the Esophagus , 2005, Digestive diseases and sciences.

[14]  R. Fitzgerald Barrett’s oesophagus and oesophageal adenocarcinoma: how does acid interfere with cell proliferation and differentiation? , 2005, Gut.

[15]  G. Groisman,et al.  Expression of the intestinal marker Cdx2 in the columnar-lined esophagus with and without intestinal (Barrett's) metaplasia , 2004, Modern Pathology.

[16]  P. A. Gregory,et al.  Regulation of UDP glucuronosyltransferases in the gastrointestinal tract. , 2004, Toxicology and applied pharmacology.

[17]  M. Oren,et al.  Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. , 2004, American journal of physiology. Cell physiology.

[18]  M. Klein,et al.  Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: similarity to human Barrett's esophagus , 2004, Laboratory Investigation.

[19]  Y. Jan,et al.  Aberrant expression of CDX2 is closely related to the intestinal metaplasia and MUC2 expression in intraductal papillary neoplasm of the liver in hepatolithiasis , 2004, Laboratory Investigation.

[20]  E. Suh,et al.  The role of Cdx proteins in intestinal development and cancer , 2004, Cancer biology & therapy.

[21]  T. Tsukamoto,et al.  Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2: inverse correlation during progression from gastric/intestinal-mixed to complete intestinal metaplasia , 2004, Journal of Cancer Research and Clinical Oncology.

[22]  Nicola J. Rinaldi,et al.  Control of Pancreas and Liver Gene Expression by HNF Transcription Factors , 2004, Science.

[23]  A. Mills,et al.  p63 is the molecular switch for initiation of an epithelial stratification program. , 2004, Genes & development.

[24]  Massimo Loda,et al.  Silencing of CDX2 Expression in Colon Cancer via a Dominant Repression Pathway* , 2003, Journal of Biological Chemistry.

[25]  H. Geddert,et al.  The role of p63 and deltaNp63 (p40) protein expression and gene amplification in esophageal carcinogenesis. , 2003, Human pathology.

[26]  M. Marchetti,et al.  Chronic acid exposure leads to activation of the cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytes , 2003, Journal of Cell Science.

[27]  P. Traber,et al.  Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene. , 2002, The Journal of biological chemistry.

[28]  K. Sugano,et al.  Aberrant Expression of CDX2 in the Gastric Mucosa With and Without Intestinal Metaplasia: Effect of Eradication of Helicobacter pylori , 2002, Helicobacter.

[29]  Kathleen I. Pinson,et al.  Villin: A marker for development of the epithelial pyloric border , 2002, Developmental dynamics : an official publication of the American Association of Anatomists.

[30]  B. Ransil,et al.  Prospective evaluation of multilayered epithelium in Barrett's esophagus , 2001, American Journal of Gastroenterology.

[31]  R. Odze,et al.  Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders. , 2001, Human pathology.

[32]  C. S. Yang,et al.  Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention. , 2001, Carcinogenesis.

[33]  R. Odze,et al.  Phenotypic Characteristics of a Distinctive Multilayered Epithelium Suggests That It Is a Precursor in the Development of Barrett's Esophagus , 2001, The American journal of surgical pathology.

[34]  J. Molkentin The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6 , 2000, The Journal of Biological Chemistry.

[35]  P. Traber,et al.  Cdx1 and cdx2 expression during intestinal development. , 2000, Gastroenterology.

[36]  S. Waldman,et al.  Intestine-specific activity of the human guanylyl cyclase C promoter is regulated by Cdx2. , 2000, Gastroenterology.

[37]  D. Sakai,et al.  Role for cGATA-5 in transcriptional regulation of the embryonic chicken pepsinogen gene by epithelial-mesenchymal interactions in the developing chicken stomach. , 2000, Developmental biology.

[38]  H. Kondoh,et al.  Pairing SOX off: with partners in the regulation of embryonic development. , 2000, Trends in genetics : TIG.

[39]  Wei Ding,et al.  An esophagogastroduodenal anastomosis model for esophageal adenocarcinogenesis in rats and enhancement by iron overload. , 1999, Carcinogenesis.

[40]  Christopher P. Crum,et al.  p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development , 1999, Nature.

[41]  D. Beer,et al.  Identification of intestinal‐type Barrett's metaplasia by using the intestine‐specific protein villin and esophageal brush cytology , 1999, Molecular carcinogenesis.

[42]  M. Rex,et al.  Region‐specific expression of chicken Sox2 in the developing gut and lung epithelium: Regulation by epithelial‐mesenchymal interactions , 1998, Developmental dynamics : an official publication of the American Association of Anatomists.

[43]  D. Beer,et al.  Abundant expression of the intestinal protein villin in Barrett's metaplasia and esophageal adenocarcinomas , 1998, Molecular carcinogenesis.

[44]  B. Liu,et al.  Development of esophageal metaplasia and adenocarcinoma in a rat surgical model without the use of a carcinogen. , 1997, Carcinogenesis.

[45]  E. Furth,et al.  CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium. , 1997, Gastroenterology.

[46]  D. Antonioli,et al.  Distribution of cytokeratin markers in Barrett's specialized columnar epithelium. , 1997, Gastroenterology.

[47]  M. Omary,et al.  Multifocal heterogeneity in villin and Ep‐CAM expression in Barrett's esophagus , 1996, International journal of cancer.

[48]  J. Baert,et al.  Expression of cytokeratin mRNAs in normal human esophageal epithelium , 1995, The Anatomical record.

[49]  S. Sinha,et al.  A functional enhancer of keratin14 is a direct transcriptional target of deltaNp63. , 2007, The Journal of investigative dermatology.

[50]  K. Sugano,et al.  Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosa , 2003, Journal of Gastroenterology.

[51]  H. Sugihara,et al.  Cell kinetic study on histogenesis of Barrett's esophagus using rat reflux model. , 2003, Scandinavian journal of gastroenterology.

[52]  J. Gordon,et al.  Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium. , 2002, Developmental biology.

[53]  S. J. Darnton,et al.  Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action. , 2002, Oncogene.

[54]  T Mach,et al.  [Barrett's metaplasia]. , 1999, Folia medica Cracoviensia.

[55]  S. Gendler,et al.  Epithelial mucin genes. , 1995, Annual review of physiology.