PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism.

[1]  S. Minoshima,et al.  Immunohistochemical and subcellular localization of parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients , 1999, Annals of neurology.

[2]  N. Shimizu,et al.  Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals , 1998, Annals of neurology.

[3]  R. Krüger,et al.  Genetic dissection of familial Parkinson's disease. , 1998, Molecular medicine today.

[4]  Georg Auburger,et al.  The ubiquitin pathway in Parkinson's disease , 1998, Nature.

[5]  M. Polymeropoulos,et al.  Deletions in the Parkin gene and genetic heterogeneity in a Greek family with early onset Parkinson’s disease , 1998, Human Genetics.

[6]  T. Gasser.  Genetics of parkinson's disease , 1998, Annals of neurology.

[7]  A. Brookes,et al.  Point Mutations (Thr240Arg and Ala311Stop) in theParkinGene , 1998 .

[8]  T Gasser,et al.  Phenotypic expression of the DYT1 mutation: A family with writer's cramp of juvenile onset , 1998, Annals of neurology.

[9]  M. H. Polymeropoulos,et al.  Alpha synuclein in neurodegenerative disorders: Murderer or accomplice? , 1998, Nature Medicine.

[10]  S. Minoshima,et al.  Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism , 1998, Nature.

[11]  Y Mizuno,et al.  A microdeletion of D6S305 in a family of autosomal recessive juvenile parkinsonism (PARK2). , 1998, Genomics.

[12]  Olaf Riess,et al.  AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease , 1998, Nature Genetics.

[13]  N. Shimizu.  HUMAN GENOME PROJECT : CURRENT STATUS, KEIO STRATEGY AND PROSPECTS , 1997 .

[14]  Robert L. Nussbaum,et al.  Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease , 1997 .

[15]  N. Shimizu,et al.  Human BAC library: construction and rapid screening. , 1997, Gene.

[16]  A A Schäffer,et al.  Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27. , 1997, American journal of human genetics.

[17]  M. Polymeropoulos,et al.  Mapping of a Gene for Parkinson's Disease to Chromosome 4q21-q23 , 1996, Science.

[18]  A. Ishikawa,et al.  Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism , 1996, Neurology.

[19]  J. Trojanowski,et al.  Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease. , 1996, The American journal of pathology.

[20]  W. V. Van Nostrand,et al.  Amyloid β-Protein Inhibits Ubiquitin-dependent Protein Degradation in Vitro(*) , 1995, The Journal of Biological Chemistry.

[21]  M. Hochstrasser.  Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. , 1995, Current opinion in cell biology.

[22]  Aaron Ciechanover,et al.  The ubiquitin-proteasome proteolytic pathway , 1994, Cell.

[23]  S. Tsuji,et al.  Familial juvenile parkinsonism , 1994, Neurology.

[24]  Yasuo Ihara,et al.  Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments , 1993, Neuron.

[25]  K. Arihiro,et al.  [Early-onset parkinsonism with diurnal fluctuation--clinical and pathological studies]. , 1993, Rinsho shinkeigaku = Clinical neurology.

[26]  C. Marsden,et al.  New insights into the cause of Parkinson's disease , 1992, Neurology.

[27]  P. Mulvihill,et al.  Filaments of Lewy bodies contain insoluble cytoskeletal elements. , 1992, The American journal of pathology.

[28]  L. Pinna.  Casein kinase 2: an 'eminence grise' in cellular regulation? , 1990, Biochimica et biophysica acta.

[29]  V. Chau,et al.  A uniform isopeptide-linked multiubiquitin chain is sufficient to target substrate for degradation in ubiquitin-mediated proteolysis. , 1990, The Journal of biological chemistry.

[30]  Alexander Varshavsky,et al.  The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis , 1989, Nature.

[31]  Y. Ihara,et al.  Ubiquitin is a component of paired helical filaments in Alzheimer's disease. , 1987, Science.

[32]  D. Calne,et al.  AETIOLOGY OF PARKINSON'S DISEASE , 1983, The Lancet.

[33]  J. Parkinson.  An Essay on the Shaking Palsy , 2002 .