Teaching cardiac autonomic function dynamics employing the Valsalva (Valsalva-Weber) maneuver.

In this report, a brief history of the Valsalva (Valsalva-Weber) maneuver is outlined, followed by an explanation on the use of this approach for the evaluation of cardiac autonomic function based on underlying heart rate changes. The most important methodological and interpretative aspects of the Valsalva-Weber maneuver are critically updated, and some guidelines are established for simple application of the maneuver in a teaching or research laboratory setting. These include the hemodynamic and cardiac autonomic mechanisms involved, technical aspects such as the intensity and duration of the expiratory straining, frequency of maneuver sessions, training and posture of the individuals tested, different time- and grade change-dependent indexes of heart interval variation, and clinical application of the maneuver.

[1]  L. Lunsford,et al.  Surgery for acoustic neurinomas. , 1991, Journal of neurosurgery.

[2]  P A Low,et al.  Autonomic Nervous System Function , 1993, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[3]  N. Accornero,et al.  Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease and multiple system atrophy with autonomic failure , 2000, Movement disorders : official journal of the Movement Disorder Society.

[4]  J R Hampton,et al.  Assessment of Methods for Estimating Autonomic Nervous Control of the Heart in Patients with Diabetes Mellitus , 1978, Diabetes.

[5]  L. Sawin,et al.  Renal Sympathetic Nerve Activity and the Exaggerated Natriuresis of the Spontaneous Hypertensive Rat , 1981, Hypertension.

[6]  D. Paprika,et al.  Measures of cardiovascular autonomic regulation derived from spontaneous methods and the Valsalva maneuver , 2003, Autonomic Neuroscience.

[7]  D. Ewing,et al.  Heart rate response to Valsalva manoeuvre. Reproducibility in normals, and relation to variation in resting heart rate in diabetics. , 1977, British heart journal.

[8]  L. Gallo,et al.  Degeneration of the Cardiac Nerves in Chagas' Disease: Further Studies , 1969, Circulation.

[9]  J. Kalbfleisch,et al.  Evaluation of the heart rate response to the Valsalva maneuver. , 1978, American heart journal.

[10]  A. F. Lyon,et al.  A reappraisal of the circulatory effects of the Valsalva maneuver. , 1965, The American journal of medicine.

[11]  P. Stein,et al.  Insights from the study of heart rate variability. , 1999, Annual review of medicine.

[12]  E. Sharpey-Schafer Effects of respiratory acts on the circulation , 1965 .

[13]  L. Rodriguez,et al.  Valsalva maneuver: a test of the functional state of cardiac innervation in Chagasic myocarditis. , 1988, International journal of cardiology.

[14]  D. Ewing,et al.  The Value of Cardiovascular Autonomic Function Tests: 10 Years Experience in Diabetes , 1985, Diabetes Care.

[15]  E. Elisberg HEART RATE RESPONSE TO THE VALSALVA MANEUVER AS A TEST OF CIRCULATORY INTEGRITY. , 1963, JAMA.

[16]  G. Gensini,et al.  Prognostic value of baroreflex sensitivity assessed by phase IV of Valsalva manoeuvre in patients with mild‐to‐moderate heart failure , 2000, European journal of heart failure.

[17]  A. Levin,et al.  A simple test of cardiac function based upon the heart rate changes induced by the Valsalva maneuver. , 1966, The American journal of cardiology.

[18]  B. Maciel,et al.  Cardiac autonomic impairment and early myocardial damage involving the right ventricle are independent phenomena in Chagas' disease. , 1998, International journal of cardiology.

[19]  B. Zweifach Handbook of Physiology. Circulation , 1966 .

[20]  G Mancia,et al.  Reflex control of the human cardiovascular system. , 1986, Reviews of physiology, biochemistry and pharmacology.

[21]  A. Ribeiro,et al.  The Valsalva maneuver in Chagas disease patients without cardiopathy. , 2002, International Journal of Cardiology.

[22]  L. F. Junqueira,et al.  Impaired autonomic control of heart interval changes to Valsalva manoeuvre in Chagas' disease without overt manifestation , 2002, Autonomic Neuroscience.

[23]  A. Camm,et al.  Arterial baroreflex sensitivity assessed from phase IV of the Valsalva maneuver. , 1996, The American journal of cardiology.

[24]  A. Ajayi,et al.  Cardiac autonomic function in Blacks with congestive heart failure: vagomimetic action, alteration in sympathovagal balance, and the effect of ACE inhibition on central and peripheral vagal tone. , 2001, Cellular and molecular biology.

[25]  B. J. Peters,et al.  Alterations of postural and Valsalva responses in coronary heart disease. , 1977, The American journal of physiology.

[26]  A. Gaber,et al.  Reliability and Validity of Cardiovascular and Vasomotor Autonomic Function Tests , 1994, Diabetes Care.

[27]  L. Gallo,et al.  Chagas' heart disease as an experimental model for studies of cardiac autonomic function in man. , 1982, Mayo Clinic proceedings.

[28]  W. Hörl,et al.  A preceding exchange with polyglucose versus glucose solution modifies peritoneal equilibration test results. , 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[29]  R GORLIN,et al.  The Valsalva maneuver as a test of cardiac function; pathologic physiology and clinical significance. , 1957, The American journal of medicine.

[30]  W. Hamilton,et al.  PHYSIOLOGIC RELATIONSHIPS BETWEEN INTRATHORACIC, INTRASPINAL AND ARTERIAL PRESSURES , 1936 .

[31]  D. Spodick,et al.  Effect of beta-adrenergic blockade on beat-to-beat response to Valsalva manoeuvre. , 1974, British heart journal.

[32]  R. Looga The bradycardic response to the Valsalva manoeuvre in normal man. , 2001, Respiration physiology.

[33]  J. Halter,et al.  Sensitivity of R-R Variation and Valsalva Ratio in Assessment of Cardiovascular Diabetic Autonomic Neuropathy , 1987, Diabetes Care.

[34]  A. Malliani,et al.  Cardiovascular Neural Regulation Explored in the Frequency Domain , 1991, Circulation.

[35]  D. Santoro,et al.  Autonomic dysfunction in uremia. , 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[36]  T. Caeiro,et al.  Baroreceptor Reflex Sensitivity Index Derived from Phase 4 of the Valsalva Maneuver , 1981, Hypertension.

[37]  Yih-Ru Wu,et al.  A Longitudinal Cardiovascular Autonomic Function Study in Mild Guillain-Barré Syndrome , 2002, European Neurology.

[38]  D. Eckberg Parasympathetic cardiovascular control in human disease: a critical review of methods and results. , 1980, The American journal of physiology.

[39]  M. Condorelli,et al.  Valsalva maneuver in the assessment of baroreflex responsiveness in borderline hypertensives. , 1983, Cardiology.

[40]  D. Ewing Cardiovascular reflexes and autonomic neuropathy. , 1978, Clinical science and molecular medicine.

[41]  V. Derbes,et al.  Valsalva's maneuver and Weber's experiment. , 1955, The New England journal of medicine.

[42]  P. Stein,et al.  Heart rate variability: a measure of cardiac autonomic tone. , 1994, American heart journal.

[43]  C. Rodolico,et al.  Cardiovascular autonomic control in Becker muscular dystrophy , 2001, Journal of the Neurological Sciences.

[44]  G. Barker,et al.  Diffusion-weighted imaging of the spinal cord and optic nerve , 2001, Journal of the Neurological Sciences.

[45]  M. Ducher,et al.  Limits of clinical tests to screen autonomic function in diabetes type 1. , 2001, Diabetes & metabolism.

[46]  L. F. Junqueira Júnior Ambulatory assessment of cardiac autonomic function in Chagas' heart disease patients based on indexes of R-R interval variation in the Valsalva maneuver. , 1990, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[47]  R. F. Rushmer Circulatory effects of three modifications of the Valsalva experiment: an experimental survey. , 1947, American heart journal.

[48]  A J Tajik,et al.  The Valsalva maneuver and response revisited. , 1986, Mayo Clinic proceedings.

[49]  D J Ewing,et al.  Autonomic function in patients with chronic renal failure on intermittent haemodialysis. , 1975, Nephron.

[50]  W. Singer,et al.  Influence of posture on the Valsalva manoeuvre. , 2001, Clinical science.