Connections of area 8 with area 6 in the brain of the macaque monkey

The corticocortical connections between the arcuate area (Walker's areas 8A and 45 or Brodmann's area 8) and the premotor and supplementary motor areas (Vogts' area 6) in the brain of the macaque monkey were studied microscopically with wheat germ agglutinin‐conjugated horseradish peroxidase (WGA‐HRP), which was injected into Brodmann's area 8 primarily to elucidate the projections of area 8 into area 6. In addition, in the same material, the pattern of connections between the arcuate area and area 46 of the prefrontal cortex was studied. On the basis of the findings of the present study, an anatomical cortical hierarchy for areas 8, 6, and 46 is discussed.

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