Connecting Transistors and Proteins

We connect transistors and proteins in two ways. The first is by showing that they have much in common as fundamental devices of electronics and life. The second is by describing how an evolvable wiring of electronic devices can parallel the wiring of proteins into genetic regulatory networks. We then transform this connection into a methodology for the study of the evolutionary properties of circuits. The approach is based on the use of analog electronic circuit simulators. We present an example of implementation with the first results obtained

[1]  A. Holmes-Siedle,et al.  Semiconductor Devices , 1976, 2018 International Semiconductor Conference (CAS).

[2]  J. Davies,et al.  Molecular Biology of the Cell , 1983, Bristol Medico-Chirurgical Journal.

[3]  Wen-Hsiung Li,et al.  Fundamentals of molecular evolution , 1990 .

[4]  D. Mindell Fundamentals of molecular evolution , 1991 .

[5]  Howard H. Pattee,et al.  Artificial Life Needs a Real Epistemology , 1995, ECAL.

[6]  P. Halling Proteins: Structures and molecular properties (2nd edition). by Thomas E. Creighton, W. H. Freeman, New York, 1992, xiii + 512 pp, price £22.95. ISBN 0‐7167‐7030‐X , 1995 .

[7]  M Conrad,et al.  Molecular and evolutionary computation: the tug of war between context freedom and context sensitivity. , 1999, Bio Systems.

[8]  N. Packard,et al.  Levels of Compartmentalization in Alife , 2000 .

[9]  John S. McCaskill,et al.  Open Problems in Artificial Life , 2000, Artificial Life.

[10]  Shane S. Sturrock,et al.  Time Warps, String Edits, and Macromolecules – The Theory and Practice of Sequence Comparison . David Sankoff and Joseph Kruskal. ISBN 1-57586-217-4. Price £13.95 (US$22·95). , 2000 .

[11]  A. Telser Molecular Biology of the Cell, 4th Edition , 2002 .

[12]  B. Alberts,et al.  Molecular Biology of the Cell 4th edition , 2007 .

[13]  Dario Floreano,et al.  Evolution of analog networks using local string alignment on highly reorganizable genomes , 2004, Proceedings. 2004 NASA/DoD Conference on Evolvable Hardware, 2004..