IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade

[1]  J. Wahren,et al.  New Tricks by an Old Dog , 2008, Experimental diabetes research.

[2]  W. Bahou,et al.  Development of Hepatocellular Carcinoma in Iqgap2-Deficient Mice Is IQGAP1 Dependent , 2008, Molecular and Cellular Biology.

[3]  Ido Amit,et al.  Regulation of MAPKs by growth factors and receptor tyrosine kinases. , 2007, Biochimica et biophysica acta.

[4]  Michalis V. Karamouzis,et al.  Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets , 2007, Nature Reviews Drug Discovery.

[5]  Alfred Wittinghofer,et al.  GEFs and GAPs: Critical Elements in the Control of Small G Proteins , 2007, Cell.

[6]  J. Pouysségur,et al.  The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition , 2007, Oncogene.

[7]  K. Kaibuchi,et al.  IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth , 2007, Journal of Cell Science.

[8]  Suzanne Schubbert,et al.  Deregulated Ras signaling in developmental disorders: new tricks for an old dog. , 2007, Current opinion in genetics & development.

[9]  E. Nishida,et al.  ERK MAP kinase in G1 cell cycle progression and cancer , 2006, Cancer science.

[10]  O. Meyuhas,et al.  Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. , 2006, Trends in biochemical sciences.

[11]  L. Cantley,et al.  Ras, PI(3)K and mTOR signalling controls tumour cell growth , 2006, Nature.

[12]  D. Sacks,et al.  IQGAP1 in cellular signaling: bridging the GAP. , 2006, Trends in cell biology.

[13]  R. Assoian,et al.  Regulation of growth factor signaling and cell cycle progression by cell adhesion and adhesion-dependent changes in cellular tension. , 2005, Cytokine & growth factor reviews.

[14]  K. Kaibuchi,et al.  IQGAP1: a key regulator of adhesion and migration , 2005, Journal of Cell Science.

[15]  Hans Clevers,et al.  Self-Renewal and Cancer of the Gut: Two Sides of a Coin , 2005, Science.

[16]  Mike Tyers,et al.  How Cells Coordinate Growth and Division , 2004, Current Biology.

[17]  T. Akiyama,et al.  Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration. , 2004, Developmental cell.

[18]  Michael F. Olson,et al.  RAS and RHO GTPases in G1-phase cell-cycle regulation , 2004, Nature Reviews Molecular Cell Biology.

[19]  K. Kaibuchi,et al.  Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact. , 2003, Molecular biology of the cell.

[20]  D. Sacks,et al.  IQGAP1 Is a Component of Cdc42 Signaling to the Cytoskeleton* , 2002, The Journal of Biological Chemistry.

[21]  S. Kuroda,et al.  Rac1 and Cdc42 Capture Microtubules through IQGAP1 and CLIP-170 , 2002, Cell.

[22]  R. Bernards,et al.  A System for Stable Expression of Short Interfering RNAs in Mammalian Cells , 2002, Science.

[23]  D. Sacks,et al.  The Effect of IQGAP1 on XenopusEmbryonic Ectoderm Requires Cdc42* , 2001, The Journal of Biological Chemistry.

[24]  M. Cobb,et al.  Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. , 2001, Endocrine reviews.

[25]  R. Bronson,et al.  Gastric Hyperplasia in Mice Lacking the Putative Cdc42 Effector IQGAP1 , 2000, Molecular and Cellular Biology.

[26]  T. P. Neufeld,et al.  Connections between growth and the cell cycle. , 1998, Current opinion in cell biology.

[27]  N. Ahn,et al.  Signal transduction through MAP kinase cascades. , 1998, Advances in cancer research.

[28]  G. Bloom,et al.  IQGAP1, a Rac- and Cdc42-binding Protein, Directly Binds and Cross-links Microfilaments , 1997, The Journal of cell biology.

[29]  J. Downward,et al.  Cell cycle: Routine role for Ras , 1997, Current Biology.

[30]  B. Gumbiner,et al.  Cell contact-dependent signaling. , 1996, Developmental biology.

[31]  N. Nomura,et al.  Identification of IQGAP as a Putative Target for the Small GTPases, Cdc42 and Rac1* , 1996, The Journal of Biological Chemistry.

[32]  D. Church,et al.  The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases , 1996, Molecular and cellular biology.

[33]  P. Polakis,et al.  IQGAP1, a calmodulin‐binding protein with a rasGAP‐related domain, is a potential effector for cdc42Hs. , 1996, The EMBO journal.

[34]  J. Settleman,et al.  Identification of a human rasGAP-related protein containing calmodulin-binding motifs. , 1994, The Journal of biological chemistry.

[35]  M. Itoh,et al.  Submembranous junctional plaque proteins include potential tumor suppressor molecules , 1993, The Journal of cell biology.

[36]  H Stein,et al.  Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. , 1984, Journal of immunology.

[37]  F L STONE,et al.  TWO SIDES OF THE COIN. , 1963, Journal of medical education.