The crystal structure and molecular conformation of threo 5-methylmetadone in relation to opioid receptor binding
暂无分享,去创建一个
[1] M. Froimowitz. Conformation-activity study of methadone and related compounds. , 1982, Journal of medicinal chemistry.
[2] D. L. Larson,et al. Synthesis, X-ray crystallographic determination, and opioid activity of erythro-5-methylmethadone enantiomers. Evidence which suggests that mu and delta opioid receptors possess different stereochemical requirements. , 1982, Journal of medicinal chemistry.
[3] P. Portoghese,et al. Stereochemical studies on medicinal agents. 21. Investigation of the role of conformational factors in the action of diphenylpropylamines. Synthesis and analgetic potency of 5-methylmethadone diastereomers. , 1976, Journal of medicinal chemistry.
[4] P. Portoghese,et al. Stereochemical studies on medicinal agents. 20. Absolute configuration and analgetic potency alpha-promedol enantiomers. The role of the C-4 chiral center in conferring stereoselectivity in axial- and equatorial-phenyl prodine congeners. , 1976, Journal of medicinal chemistry.
[5] G. Loew,et al. Quantum chemical studies of methadone. , 1976, Journal of medicinal chemistry.
[6] E. Shefter. Crystal structures of analgesics. Hydrochlorides of (minus)-isomethadone, alpha-methadol, and alpha-methadyl acetate. , 1974, Journal of medicinal chemistry.
[7] P. Portoghese,et al. Stereochemical studies on medicinal agents. VI. Bicyclic bases. Synthesis and pharmacology of epimeric bridged analogs of meperidine, 2-methyl-5-phenyl-5-carbethoxy-2-azabicyclo[2.2.1]heptane. , 1968, Journal of medicinal chemistry.
[8] P. Portoghese. Stereochemical factors and receptor interactions associated with narcotic analgesics. , 1966, Journal of pharmaceutical sciences.
[9] A. W. Hanson,et al. The crystal structure and absolute configuration of the monoclinic form of d‐methadone hydrobromide , 1958 .
[10] N. J. Harper,et al. ANALGESICS AND THEIR ANTAGONISTS: SOME STERIC AND CHEMICAL CONSIDERATIONS , 1956, The Journal of pharmacy and pharmacology.
[11] A H BECKETT,et al. SYNTHETIC ANALGESICS: STEREOCHEMICAL CONSIDERATIONS , 1954, The Journal of pharmacy and pharmacology.
[12] N. B. Eddy,et al. The Isomethadols and their Acetyl Derivatives , 1952 .
[13] E. Mosettig,et al. CHEMISTRY AND PHARMACOLOGY OF THE METHADOLS1 AND ACETYLMETHADOLS2 , 1952 .