Investigation of alternative data types for time-resolved optical tomography

The technique known as optical tomography involves reconstructing a two- or three-dimensional map of the internal distribution of optical properties of an object from a series of measurements made of the light transmitted between pairs of points on the surface. In this paper we consider the form in which time-resolved measurements should be provided in order to achieve optimum simultaneous reconstruction of scatter and absorption. Various data types are proposed, and an examination is reported of the effect of stochastic noise on their intrinsic uncertainty, and on the ability to uniquely specify the global internal optical properties using pairs of different data types.

[1]  D. Delpy,et al.  Time-resolved optical imaging of a solid tissue-equivalent phantom. , 1995, Applied optics.

[2]  H. Wabnitz,et al.  Time-resolved imaging of solid phantoms for optical mammography. , 1997, Applied optics.

[3]  S R Arridge,et al.  Statistical basis for the determination of optical pathlength in tissue. , 1995, Physics in medicine and biology.

[4]  S. Arridge,et al.  Optical imaging in medicine: II. Modelling and reconstruction , 1997, Physics in medicine and biology.

[5]  H Eda,et al.  Optical tomography by the temporally extrapolated absorbance method. , 1996, Applied optics.

[6]  K D Paulsen,et al.  Simultaneous reconstruction of optical absorption and scattering maps in turbid media from near-infrared frequency-domain data. , 1995, Optics letters.

[7]  Jochen G. Koelzer,et al.  Characterization of female breasts in vivo by time-resolved and spectroscopic measurements in the near infrared spectroscopy. , 1996, Journal of biomedical optics.

[8]  Philip Kohn,et al.  Image Reconstruction of the Interior of Bodies That Diffuse Radiation , 1990, Science.

[9]  S R Arridge,et al.  Direct calculation of the moments of the distribution of photon time of flight in tissue with a finite-element method. , 1995, Applied optics.

[10]  D. Boas,et al.  Experimental images of heterogeneous turbid media by frequency-domain diffusing-photon tomography. , 1995, Optics letters.

[11]  Harry L. Graber,et al.  Near-infrared absorption imaging of dense scattering media by steady-state diffusion tomography , 1993, Photonics West - Lasers and Applications in Science and Engineering.

[12]  S R Arridge,et al.  The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis. , 1992, Physics in medicine and biology.

[13]  Kevin Wells,et al.  UCL multichannel time-resolved system for optical tomography , 1997, Photonics West - Biomedical Optics.

[14]  S R Arridge,et al.  Direct calculation with a finite-element method of the Laplace transform of the distribution of photon time of flight in tissue. , 1997, Applied optics.