Berberine

[1]  Jian-Dong Jiang,et al.  Gut Microbiota-Regulated Pharmacokinetics of Berberine and Active Metabolites in Beagle Dogs After Oral Administration , 2018, Front. Pharmacol..

[2]  Yan-Ling Zhao,et al.  Natural products berberine and curcumin exhibited better ameliorative effects on rats with non-alcohol fatty liver disease than lovastatin. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[3]  M. Goudarzi,et al.  Hepatoprotective effect of berberine against methotrexate induced liver toxicity in rats. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[4]  F. Watt,et al.  Osteoarthritis biomarkers: year in review. , 2017, Osteoarthritis and cartilage.

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[7]  B. Saha,et al.  Differential modes of photosensitisation in cancer cells by berberine and coralyne , 2017, Free radical research.

[8]  Xiao Zheng,et al.  Preparation, pharmacokinetics and tumour‐suppressive activity of berberine liposomes , 2017, The Journal of pharmacy and pharmacology.

[9]  B. Lyoussi,et al.  Berberis vulgaris L. effects on oxidative stress and liver injury in lead-intoxicated mice , 2017, Journal of complementary & integrative medicine.

[10]  H. Hosseinzadeh,et al.  Berberis Vulgaris and Berberine: An Update Review , 2016, Phytotherapy research : PTR.

[11]  Z. Cai,et al.  Role of berberine in Alzheimer’s disease , 2016, Neuropsychiatric disease and treatment.

[12]  M. Luo,et al.  Study progress of berberine for treating cardiovascular disease , 2015, Chronic diseases and translational medicine.

[13]  Shan-Chi Liu,et al.  Berberine attenuates CCN2-induced IL-1β expression and prevents cartilage degradation in a rat model of osteoarthritis. , 2015, Toxicology and applied pharmacology.

[14]  N. Colburn,et al.  Berberine regulates AMP‐activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice , 2015, Molecular carcinogenesis.

[15]  Jian-Dong Jiang,et al.  Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters , 2015, Journal of Translational Medicine.

[16]  K. Chopra,et al.  Current knowledge and pharmacological profile of berberine: An update. , 2015, European journal of pharmacology.

[17]  W. Ni,et al.  Berberine as a promising anti-diabetic nephropathy drug: An analysis of its effects and mechanisms. , 2015, European journal of pharmacology.

[18]  Xi Chen,et al.  Transforming berberine into its intestine-absorbable form by the gut microbiota , 2015, Scientific Reports.

[19]  Tian-Yu Zhao,et al.  Application of Berberine on Treating Type 2 Diabetes Mellitus , 2015, International journal of endocrinology.

[20]  Yanyun Zhao,et al.  Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. , 2015, Journal of ethnopharmacology.

[21]  Yanwen Wang,et al.  Berberine decreases cholesterol levels in rats through multiple mechanisms, including inhibition of cholesterol absorption. , 2014, Metabolism: clinical and experimental.

[22]  A. A. Abdel Moneim,et al.  The potential effect of berberine in mercury-induced hepatorenal toxicity in albino rats. , 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[23]  G. Derosa,et al.  Dietary and nutraceutical approach to type 2 diabetes , 2014, Archives of medical science : AMS.

[24]  Jing Li,et al.  Hepatoprotective effects of berberine on liver fibrosis via activation of AMP-activated protein kinase. , 2014, Life sciences.

[25]  Jian-Dong Jiang,et al.  Excretion of berberine and its metabolites in oral administration in rats. , 2013, Journal of pharmaceutical sciences.

[26]  D. Ghareeb,et al.  In vitro biological assessment of berberis vulgaris and its active constituent, berberine: antioxidants, anti-acetylcholinesterase, anti-diabetic and anticancer effects , 2013, BMC Complementary and Alternative Medicine.

[27]  F. Lu,et al.  Berberine in the Treatment of Type 2 Diabetes Mellitus: A Systemic Review and Meta-Analysis , 2012, Evidence-based complementary and alternative medicine : eCAM.

[28]  Ming Zhang,et al.  Berberine in type 2 diabetes therapy: a new perspective for an old antidiarrheal drug? , 2012 .

[29]  F. Pelliccia,et al.  Long-term effects of nutraceuticals (berberine, red yeast rice, policosanol) in elderly hypercholesterolemic patients , 2011, Advances in therapy.

[30]  Jian-ning Sun,et al.  Berberine attenuates cardiac dysfunction in hyperglycemic and hypercholesterolemic rats. , 2011, European journal of pharmacology.

[31]  P. Bhutada,et al.  Protection of cholinergic and antioxidant system contributes to the effect of berberine ameliorating memory dysfunction in rat model of streptozotocin-induced diabetes , 2011, Behavioural Brain Research.

[32]  Xing Tang,et al.  Bioavailability Study of Berberine and the Enhancing Effects of TPGS on Intestinal Absorption in Rats , 2011, AAPS PharmSciTech.

[33]  Li-Dong Wu,et al.  Protective Effects of Berberine in an Experimental Rat Osteoarthritis Model , 2011, Phytotherapy research : PTR.

[34]  R. Domitrović,et al.  Hepatoprotective activity of berberine is mediated by inhibition of TNF-α, COX-2, and iNOS expression in CCl(4)-intoxicated mice. , 2011, Toxicology.

[35]  Wei-Jia Kong,et al.  Protein kinase D activation stimulates the transcription of the insulin receptor gene , 2010, Molecular and Cellular Endocrinology.

[36]  L. Saccá,et al.  Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study. , 2010, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[37]  M. Yuen,et al.  Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats , 2010, Chinese medicine.

[38]  V. Mercurio,et al.  Cardiovascular and metabolic effects of Berberine. , 2010, World journal of cardiology.

[39]  M. Kheir,et al.  Acute toxicity of berberine and its correlation with the blood concentration in mice. , 2010, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[40]  Lisa M. Miller,et al.  Berberine and plant stanols synergistically inhibit cholesterol absorption in hamsters. , 2010, Atherosclerosis.

[41]  A. Dhir,et al.  Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders , 2010, Phytotherapy research : PTR.

[42]  Wei-Jia Kong,et al.  Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. , 2010, Metabolism: clinical and experimental.

[43]  R. Pi,et al.  Neuropharmacological and pharmacokinetic properties of berberine: a review of recent research , 2009 .

[44]  George Perry,et al.  The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease , 2009, Journal of neurochemistry.

[45]  F. Lu,et al.  Facilitating effects of berberine on rat pancreatic islets through modulating hepatic nuclear factor 4 alpha expression and glucokinase activity. , 2008, World journal of gastroenterology.

[46]  K. Huse,et al.  Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver , 2008, Drug Metabolism and Disposition.

[47]  H. Hosseinzadeh,et al.  Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine , 2008, Phytotherapy research : PTR.

[48]  S. Kulkarni,et al.  On the mechanism of antidepressant-like action of berberine chloride. , 2008, European journal of pharmacology.

[49]  G. Ning,et al.  Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. , 2008, The Journal of clinical endocrinology and metabolism.

[50]  Le Zhang,et al.  Chronic effects of berberine on blood, liver glucolipid metabolism and liver PPARs expression in diabetic hyperlipidemic rats. , 2008, Biological & pharmaceutical bulletin.

[51]  Jianping Ye,et al.  Efficacy of berberine in patients with type 2 diabetes mellitus. , 2008, Metabolism: clinical and experimental.

[52]  Hyun-Joung Lim,et al.  Berberine-induced LDLR up-regulation involves JNK pathway. , 2007, Biochemical and biophysical research communications.

[53]  C. Hyun,et al.  Berberine activates GLUT1-mediated glucose uptake in 3T3-L1 adipocytes. , 2007, Biological & pharmaceutical bulletin.

[54]  Ying-Chih Lin,et al.  Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. , 2007, Life sciences.

[55]  T. Saido,et al.  Berberine alters the processing of Alzheimer's amyloid precursor protein to decrease Abeta secretion. , 2007, Biochemical and biophysical research communications.

[56]  Ji-won Park,et al.  Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte , 2006, Experimental & Molecular Medicine.

[57]  Feiqi Zhu,et al.  Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer's disease , 2006, BMC Neuroscience.

[58]  N. Nakamura,et al.  Pharmacokinetics of Berberine and Its Main Metabolites in Conventional and Pseudo Germ-Free Rats Determined by Liquid Chromatography/Ion Trap Mass Spectrometry , 2006, Drug Metabolism and Disposition.

[59]  Yuebo Zhang,et al.  Berberine inhibits 3T3-L1 adipocyte differentiation through the PPARγ pathway , 2006 .

[60]  D. James,et al.  Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States , 2006, Diabetes.

[61]  Yu Huang,et al.  Cardiovascular actions of berberine. , 2006, Cardiovascular drug reviews.

[62]  J. Brusq,et al.  Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine Published, JLR Papers in Press, February 28, 2006. , 2006, Journal of Lipid Research.

[63]  K. Ingkaninan,et al.  Acetylcholinesterase inhibitors from Stephania venosa tuber , 2006, The Journal of pharmacy and pharmacology.

[64]  K. Yoo,et al.  Berberry extract reduces neuronal damage and N-Methyl-D-aspartate receptor 1 immunoreactivity in the gerbil hippocampus after transient forebrain ischemia. , 2006, Biological & pharmaceutical bulletin.

[65]  Yi Ding,et al.  Kinetic difference of berberine between hippocampus and plasma in rat after intravenous administration of Coptidis rhizoma extract. , 2005, Life sciences.

[66]  Jingwen Liu,et al.  Extracellular Signal-Regulated Kinase–Dependent Stabilization of Hepatic Low-Density Lipoprotein Receptor mRNA by Herbal Medicine Berberine , 2005, Arteriosclerosis, thrombosis, and vascular biology.

[67]  Satoru Inaba,et al.  Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins , 2004, Nature Medicine.

[68]  T. Tsai,et al.  Hepatobiliary excretion of berberine. , 2004, Drug metabolism and disposition: the biological fate of chemicals.

[69]  Fang Wang,et al.  Effects of berberine on potassium currents in acutely isolated CA1 pyramidal neurons of rat hippocampus , 2004, Brain Research.

[70]  Xianghong Zeng,et al.  Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. , 2003, The American journal of cardiology.

[71]  J. P. Fawcett,et al.  The antihyperglycaemic activity of berberine arises from a decrease of glucose absorption. , 2003, Planta medica.

[72]  J. P. Fawcett,et al.  The involvement of P-glycoprotein in berberine absorption. , 2002, Pharmacology & toxicology.

[73]  R. Tan,et al.  Monoamine Oxidase Inhibitors from Rhizoma of Coptis chinensis , 2001, Planta medica.

[74]  X. Yao,et al.  Vasorelaxant and antiproliferative effects of berberine. , 2000, European journal of pharmacology.

[75]  A. Gilani,et al.  Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. , 2000, Fitoterapia.

[76]  J. Silverman,et al.  Inhibition of P-Glycoprotein by D-α-Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS) , 1999, Pharmaceutical Research.

[77]  Y. X. Wang,et al.  Ionic mechanism responsible for prolongation of cardiac action-potential duration by berberine. , 1997, Journal of cardiovascular pharmacology.

[78]  N. Chou,et al.  Mechanical and electrophysiological effects of 8‐oxoberberine (JKL1073A) on atrial tissue , 1996, British journal of pharmacology.

[79]  J. Sánchez-Chapula,et al.  Increase in action potential duration and inhibition of the delayed rectifier outward current IK by berberine in cat ventricular myocytes , 1996, British journal of pharmacology.

[80]  H. S. Kim,et al.  Inhibitory Effects of Protoberberine Alkaloids from the Roots of Coptis japonica on Catecholamine Biosynthesis in PC12 Cells , 1996, Planta medica.

[81]  F. R. Neto.  Electropharmacological effects of berberine on canine cardiac Purkinje fibres and ventricular muscle and atrial muscle of the rabbit , 1993 .

[82]  C. Sninsky,et al.  Effect of berberine on myoelectric activity and transit of the small intestine in rats. , 1989, Gastroenterology.

[83]  B. Maciel,et al.  Cardiovascular effects of berberine in patients with severe congestive heart failure , 1988, Clinical cardiology.

[84]  A. Ghosh,et al.  Leishmania donovani: amastigote inhibition and mode of action of berberine. , 1985, Experimental parasitology.

[85]  L. Rothenberg,et al.  Digital angiography in the pediatric patient with congenital heart disease: comparison with standard methods. , 1983, Circulation.

[86]  R. Sack,et al.  Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins , 1982, Infection and immunity.

[87]  D. Lim,et al.  Influence of berberine on the blood pressure of rabbits , 1980 .

[88]  Ramesh C. Gupta.  Nutraceuticals in arthritis , 2021, Nutraceuticals.

[89]  Ramesh C. Gupta,et al.  Osteoarthritis Biomarkers , 2019, Biomarkers in Toxicology.

[90]  Hany E. A. Ahmed,et al.  Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats. , 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[91]  Yue-qin Tang,et al.  A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. , 2015, Molecular bioSystems.

[92]  E. Martínez-Abundis,et al.  Effect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretion. , 2013, Metabolic syndrome and related disorders.

[93]  Wei-Jia Kong,et al.  Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression. , 2009, Metabolism: clinical and experimental.

[94]  Jianping Ye,et al.  Berberine improves glucose metabolism through induction of glycolysis. , 2008, American journal of physiology. Endocrinology and metabolism.

[95]  G. King,et al.  Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes , 2007, Nature Clinical Practice Endocrinology &Metabolism.

[96]  Siu-Chun Hui,et al.  Effect of berberine on regression of pressure-overload induced cardiac hypertrophy in rats. , 2002, The American journal of Chinese medicine.

[97]  Jun Liang Yu,et al.  Interaction of berberine with human platelet α2 adrenoceptors , 1991 .

[98]  M. Torii,et al.  In vitro effects of berberine sulphate on the growth and structure of Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. , 1991, Annals of tropical medicine and parasitology.

[99]  T. Yip,et al.  A biochemical study on the hypotensive effect of berberine in rats. , 1979, General pharmacology.