A Calorie-Restricted DASH Diet Reduces Body Fat and Maintains Muscle Strength in Obese Older Adults

This study examined the effect of the Dietary Approaches to Stop Hypertension (DASH) diet containing lean red meat on measures of body composition and muscle strength in a cohort of obese adults 65 and older; 36 males (n = 15) and females (n = 21) consumed 1800 kcal/day for 12 weeks under controlled feeding conditions. The study diet included daily intakes of 126 g of meat. Measures of body composition and muscle strength were obtained at weeks 0, 3, 6, 9, and 12. Breakfast, lunch, and dinner were provided every day for 12 weeks, and equal portions of meat were distributed at each meal. Significant effects of the study diet were detected across time for total body weight, body mass index (BMI), waist circumference, hip circumference, body fat percentage, absolute fat mass (AFM), and blood pressure such that a decrease (p < 0.001) was observed over 12 weeks. Significant effects of the study diet were detected across time for sit/stand (p < 0.001) such that an increase was observed. From baseline to study end, total body weight decreased by 6.3% (p < 0.001), body fat percentage decreased by 2.5% (p < 0.001), and absolute fat mass (AFM) decreased by 4.4 kg (p < 0.001). By the study end, skeletal muscle mass (SMM) was positively correlated with handgrip strength (R2 = 0.75; p = 0.001) and resting energy expenditure (REE) (R2 = 0.29; p = 0.001). Handgrip strength, gait, balance, and resting energy expenditure (REE) were well maintained (p > 0.05) throughout the study. These findings suggest that the DASH diet has the potential to be a tool to preserve muscle strength while reducing fat mass in obese older adults.

[1]  C. Sieber Malnutrition and sarcopenia , 2019, Aging Clinical and Experimental Research.

[2]  René Rizzoli,et al.  Sarcopenia: revised European consensus on definition and diagnosis , 2018, Age and ageing.

[3]  M. Battino,et al.  Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies. , 2018, Pharmacological research.

[4]  D. Cameron-Smith,et al.  The effects of dietary protein intake on appendicular lean mass and muscle function in elderly men: a 10-wk randomized controlled trial. , 2017, The American journal of clinical nutrition.

[5]  Yunhwan Lee,et al.  Diet quality and osteosarcopenic obesity in community-dwelling adults 50 years and older. , 2017, Maturitas.

[6]  E. Feskens,et al.  The Dietary Approaches to Stop Hypertension Diet, Cognitive Function, and Cognitive Decline in American Older Women. , 2017, Journal of the American Medical Directors Association.

[7]  J. Ilich,et al.  Aging human body: changes in bone, muscle and body fat with consequent changes in nutrient intake. , 2017, The Journal of endocrinology.

[8]  Mark A Pereira,et al.  Brazilian dietary patterns and the dietary approaches to stop hypertension (DASH) diet-relationship with metabolic syndrome and newly diagnosed diabetes in the ELSA-Brasil study , 2017, Diabetology & Metabolic Syndrome.

[9]  G. Logroscino,et al.  Relationships of Dietary Patterns, Foods, and Micro- and Macronutrients with Alzheimer's Disease and Late-Life Cognitive Disorders: A Systematic Review. , 2017, Journal of Alzheimer's disease : JAD.

[10]  H. Poustchi,et al.  Adherence to the Dietary Approaches to Stop Hypertension (DASH) and risk of Nonalcoholic Fatty Liver Disease , 2016, International journal of food sciences and nutrition.

[11]  C. May,et al.  A feasibility study of implementing grip strength measurement into routine hospital practice (GRImP): study protocol , 2016, Pilot and Feasibility Studies.

[12]  Khalid Yusoff,et al.  Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study , 2015, The Lancet.

[13]  S. Kritchevsky,et al.  Protein and healthy aging. , 2015, The American journal of clinical nutrition.

[14]  E. Volpi,et al.  Protein intake and muscle function in older adults , 2015, Current opinion in clinical nutrition and metabolic care.

[15]  H. Escobar-Morreale,et al.  Surrogate Markers of Visceral Adiposity in Young Adults: Waist Circumference and Body Mass Index Are More Accurate than Waist Hip Ratio, Model of Adipose Distribution and Visceral Adiposity Index , 2014, PloS one.

[16]  Sunita Ghosh,et al.  New Insight into Fat, Muscle and Bone Relationship in Women: Determining the Threshold at Which Body Fat Assumes Negative Relationship with Bone Mineral Density , 2014, International journal of preventive medicine.

[17]  J. V. Vanden Heuvel,et al.  Effects of a DASH-like diet containing lean beef on vascular health , 2014, Journal of Human Hypertension.

[18]  M. Siervo,et al.  Osteosarcopenic obesity: the role of bone, muscle, and fat on health , 2014, Journal of cachexia, sarcopenia and muscle.

[19]  H. Leidy,et al.  Dietary protein and muscle in older persons , 2014, Current opinion in clinical nutrition and metabolic care.

[20]  J. Stevens,et al.  Development of STEADI , 2013, Health promotion practice.

[21]  N. Peel,et al.  Gait speed as a measure in geriatric assessment in clinical settings: a systematic review. , 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

[22]  J. V. Vanden Heuvel,et al.  Beef in an Optimal Lean Diet study: effects on lipids, lipoproteins, and apolipoproteins123 , 2011, The American journal of clinical nutrition.

[23]  C. Meyerhoefer,et al.  The Medical Care Costs of Obesity: an Instrumental Variables Approach , 2010, Journal of Health Economics.

[24]  S. Studenski,et al.  Gait speed and survival in older adults. , 2011, JAMA.

[25]  M. Tinetti,et al.  Summary of the Updated American Geriatrics Society/british Geriatrics Society Clinical Practice Guideline for Prevention of Falls in Older Persons , 2022 .

[26]  Rasch Analysis of the Fullerton Advanced Balance (FAB) Scale. , 2011, Physiotherapy Canada. Physiotherapie Canada.

[27]  T. Astorino,et al.  Recommendations for Improved Data Processing from Expired Gas Analysis Indirect Calorimetry , 2010, Sports medicine.

[28]  M. Inzitari,et al.  Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force , 2009, The journal of nutrition, health & aging.

[29]  D. Rose,et al.  Predicting which older adults will or will not fall using the Fullerton Advanced Balance scale. , 2008, Archives of physical medicine and rehabilitation.

[30]  D. Allison,et al.  Waist Circumference and Cardiometabolic Risk , 2007, Diabetes Care.

[31]  P. Trumbo,et al.  Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. , 2002, Journal of the American Dietetic Association.

[32]  K Huber,et al.  Appendix 2 , 2021, European Journal of Human Genetics.

[33]  E. Protas,et al.  Sensitivity of a clinical scale of balance and gait in frail nursing home residents. , 2000, Disability and rehabilitation.

[34]  Suzanne G. Leveille,et al.  Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. , 2000, The journals of gerontology. Series A, Biological sciences and medical sciences.

[35]  W. Beam,et al.  A 30-s chair-stand test as a measure of lower body strength in community-residing older adults. , 1999, Research quarterly for exercise and sport.

[36]  D. Sellen,et al.  Genetics of Criminal and Antisocial Behaviour. Ciba Foundation Symposium 194. Pp. 283. Edited by G. R. Bock & J. A. Goode. (Wiley, Chichester, 1996.) £50.00. , 1998, Journal of Biosocial Science.

[37]  G. Blackburn,et al.  Effect of degree of weight loss on health benefits. , 1995, Obesity research.

[38]  P. Thompson,et al.  ACSM's Guidelines for Exercise Testing and Prescription , 1995 .

[39]  M. Tinetti Performance‐Oriented Assessment of Mobility Problems in Elderly Patients , 1986, Journal of the American Geriatrics Society.

[40]  D. A. Seaton Losing weight. , 1966, Nursing mirror and midwives journal.