Controlled and uncontrolled asthma display distinct alveolar tissue matrix compositions

[1]  R. Dahl,et al.  Marked epithelial cell pathology and leukocyte paucity in persistently symptomatic severe asthma. , 2013, American journal of respiratory and critical care medicine.

[2]  Weining Yang,et al.  Roles of versican in cancer biology--tumorigenesis, progression and metastasis. , 2013, Histology and histopathology.

[3]  Monica Kraft,et al.  IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies. , 2012, The Journal of allergy and clinical immunology.

[4]  I. Kovalszky,et al.  Decorin–TGFβ Axis in Hepatic Fibrosis and Cirrhosis , 2012, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[5]  A. Bergqvist,et al.  Mast cell-associated alveolar inflammation in patients with atopic uncontrolled asthma. , 2011, The Journal of allergy and clinical immunology.

[6]  J. Erjefält,et al.  Altered matrix production in the distal airways of individuals with asthma , 2010, Thorax.

[7]  A. Oldberg,et al.  The role of small leucine-rich proteoglycans in collagen fibrillogenesis. , 2010, Matrix biology : journal of the International Society for Matrix Biology.

[8]  S. Holgate Novel targets of therapy in asthma , 2009, Current opinion in pulmonary medicine.

[9]  P. Black,et al.  Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease , 2008, Respiratory research.

[10]  P. Barnes Immunology of asthma and chronic obstructive pulmonary disease , 2008, Nature Reviews Immunology.

[11]  A. Gulsvik,et al.  Asthma control in Europe: a real-world evaluation based on an international population-based study. , 2007, The Journal of allergy and clinical immunology.

[12]  M. Tammi,et al.  Hyaluronan-dependent pericellular matrix. , 2007, Advanced drug delivery reviews.

[13]  P. Sterk,et al.  Asthma therapy and airway remodeling. , 2007, The Journal of allergy and clinical immunology.

[14]  R. Iozzo,et al.  The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis , 2007, The FEBS journal.

[15]  P. Roughley,et al.  SLRP interaction can protect collagen fibrils from cleavage by collagenases. , 2006, Matrix biology : journal of the International Society for Matrix Biology.

[16]  R. McAnulty,et al.  TGF-beta: its role in asthma and therapeutic potential. , 2006, Current drug targets.

[17]  M. Kosinski,et al.  Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists. , 2006, The Journal of allergy and clinical immunology.

[18]  Q. Hamid,et al.  Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: effect of hydrofluoroalkane-flunisolide. , 2005, The Journal of allergy and clinical immunology.

[19]  P. Roughley,et al.  Airway proteoglycans are differentially altered in fatal asthma , 2005, The Journal of pathology.

[20]  Marian F Young,et al.  The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. , 2005, The Journal of clinical investigation.

[21]  S. Fukuhara,et al.  Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma , 2005, Thorax.

[22]  T. Wight,et al.  Proteoglycans in atherosclerosis and restenosis: key roles for versican. , 2004, Circulation research.

[23]  G. Westergren-Thorsson,et al.  Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration , 2003, Journal of Cell Science.

[24]  T. Wight,et al.  Versican: a versatile extracellular matrix proteoglycan in cell biology. , 2002, Current opinion in cell biology.

[25]  S. Wenzel,et al.  Transbronchial biopsy as a tool to evaluate small airways in asthma , 2002, European Respiratory Journal.

[26]  Zenzo Isogai,et al.  Versican Interacts with Fibrillin-1 and Links Extracellular Microfibrils to Other Connective Tissue Networks* , 2002, The Journal of Biological Chemistry.

[27]  Richard J Martin Therapeutic significance of distal airway inflammation in asthma. , 2002, The Journal of allergy and clinical immunology.

[28]  R. Homer,et al.  Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1 , 2001, The Journal of experimental medicine.

[29]  M. Kobayashi,et al.  Elongated dermatan sulphate in post-inflammatory healing skin distributes among collagen fibrils separated by enlarged interfibrillar gaps. , 2001, The Biochemical journal.

[30]  P. Sime,et al.  Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung. , 2001, American journal of physiology. Lung cellular and molecular physiology.

[31]  L. Lichtenstein,et al.  Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts. , 2000, The Journal of pharmacology and experimental therapeutics.

[32]  R. Olivenstein,et al.  Enhanced proteoglycan deposition in the airway wall of atopic asthmatics. , 1999, American journal of respiratory and critical care medicine.

[33]  G. Canonica,et al.  Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma. , 1998, The Journal of clinical investigation.

[34]  R. Martin,et al.  Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. , 1997, American journal of respiratory cell and molecular biology.

[35]  Renato V. Iozzo,et al.  Targeted Disruption of Decorin Leads to Abnormal Collagen Fibril Morphology and Skin Fragility , 1997, Journal of Cell Biology.

[36]  R. Pauwels,et al.  GLOBAL STRATEGY FOR ASTHMA MANAGEMENT AND PREVENTION , 1996 .

[37]  E. Ruoslahti,et al.  Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta. , 1994, The Biochemical journal.

[38]  G. Raghu,et al.  Collagen synthesis by normal and fibrotic human lung fibroblasts and the effect of transforming growth factor-beta. , 1989, The American review of respiratory disease.

[39]  R. Kizek,et al.  Matrix metalloproteinases. , 2010, Current medicinal chemistry.

[40]  Wan-Wan Lin,et al.  Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis , 2009, Nature.

[41]  J. Bousquet,et al.  Sleep and allergic rhinitis. , 2008, Journal of investigational allergology & clinical immunology.

[42]  D. Broide,et al.  Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice. , 2006, American journal of physiology. Lung cellular and molecular physiology.

[43]  A. Miller-Larsson,et al.  Lung fibroblast proteoglycan production induced by serum is inhibited by budesonide and formoterol. , 2006, American journal of respiratory cell and molecular biology.

[44]  R. Djukanović,et al.  Lymphocyte and eosinophil influx into alveolar tissue in nocturnal asthma. , 1999, American journal of respiratory and critical care medicine.