Motion Management in Stereotactic Body Radiotherapy

With the technologic advancements in image guidance and dose delivery, stereotactic body radiotherapy (SBRT) is being widely used for cancer treatment in various anatomical locations as a noninvasive alternative to surgery. To deliver ablative doses to tumors with limited normal tissue toxicity, SBRT requires high accuracy in treatment setup which requires taking tumor motion into account. Techniques are also applied in SBRT to minimize tumor motion during dose delivery. This paper reviews techniques for motion management in SBRT.

[1]  Michael Flentje,et al.  Stereotactic radiotherapy for primary lung cancer and pulmonary metastases: a noninvasive treatment approach in medically inoperable patients. , 2004, International journal of radiation oncology, biology, physics.

[2]  P J Keall,et al.  The application of the sinusoidal model to lung cancer patient respiratory motion. , 2005, Medical physics.

[3]  W. Lu,et al.  Comparison of helical, maximum intensity projection (MIP), and averaged intensity (AI) 4D CT imaging for stereotactic body radiation therapy (SBRT) planning in lung cancer. , 2006, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[4]  Cedric X. Yu,et al.  Real-time intra-fraction-motion tracking using the treatment couch: a feasibility study , 2005, Physics in medicine and biology.

[5]  G J Kutcher,et al.  Deep inspiration breath-hold technique for lung tumors: the potential value of target immobilization and reduced lung density in dose escalation. , 1999, International journal of radiation oncology, biology, physics.

[6]  A Fenster,et al.  Three-dimensional ultrasound imaging. , 2000, Annual review of biomedical engineering.

[7]  K. Lam,et al.  Uncertainties in CT-based radiation therapy treatment planning associated with patient breathing. , 1996, International journal of radiation oncology, biology, physics.

[8]  Jean Pouliot,et al.  Positional stability of electromagnetic transponders used for prostate localization and continuous, real-time tracking. , 2007, International journal of radiation oncology, biology, physics.

[9]  M. Schell,et al.  Stereotactic body radiation therapy: the report of AAPM Task Group 101. , 2010, Medical physics.

[10]  Tomoki Kimura,et al.  Reproducibility of organ position using voluntary breath-hold method with spirometer for extracranial stereotactic radiotherapy. , 2003, International journal of radiation oncology, biology, physics.

[11]  Hiroshi Onishi,et al.  Clinical outcomes of stereotactic radiotherapy for stage I non-small cell lung cancer using a novel irradiation technique: patient self-controlled breath-hold and beam switching using a combination of linear accelerator and CT scanner. , 2004, Lung cancer.

[12]  G Starkschall,et al.  Respiratory-driven lung tumor motion is independent of tumor size, tumor location, and pulmonary function. , 2001, International journal of radiation oncology, biology, physics.

[13]  Hiroki Shirato,et al.  Accuracy of tumor motion compensation algorithm from a robotic respiratory tracking system: a simulation study. , 2007, Medical physics.

[14]  Shinichi Shimizu,et al.  Tumor location, cirrhosis, and surgical history contribute to tumor movement in the liver, as measured during stereotactic irradiation using a real-time tumor-tracking radiotherapy system. , 2003, International journal of radiation oncology, biology, physics.

[15]  Thierry Gevaert,et al.  Geometric accuracy of a novel gimbals based radiation therapy tumor tracking system. , 2011, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[16]  Hiroshi Onishi,et al.  CT evaluation of patient deep inspiration self-breath-holding: how precisely can patients reproduce the tumor position in the absence of respiratory monitoring devices? , 2003, Medical physics.

[17]  Andrea Bezjak,et al.  Effect of immobilization and performance status on intrafraction motion for stereotactic lung radiotherapy: analysis of 133 patients. , 2011, International journal of radiation oncology, biology, physics.

[18]  Geoffrey G. Zhang,et al.  Elastic image mapping for 4-D dose estimation in thoracic radiotherapy. , 2005, Radiation protection dosimetry.

[19]  Alexander Markovic,et al.  Quality assurance of U.S.-guided external beam radiotherapy for prostate cancer: report of AAPM Task Group 154. , 2011, Medical physics.

[20]  Paul J Keall,et al.  The first clinical implementation of electromagnetic transponder-guided MLC tracking. , 2014, Medical physics.

[21]  Paul J Keall,et al.  Retrospective analysis of artifacts in four-dimensional CT images of 50 abdominal and thoracic radiotherapy patients. , 2008, International journal of radiation oncology, biology, physics.

[22]  K. Ohara,et al.  Irradiation synchronized with respiration gate. , 1989, International journal of radiation oncology, biology, physics.

[23]  E. B. Butler,et al.  A dose-response relationship for time to bone pain resolution after stereotactic body radiotherapy (SBRT) for renal cell carcinoma (RCC) bony metastases , 2012, Acta oncologica.

[24]  Rakesh Patel,et al.  3D-Ultrasound Guided Radiation Therapy in the Post-Prostatectomy Setting , 2003, Technology in cancer research & treatment.

[25]  Sasa Mutic,et al.  The ViewRay system: magnetic resonance-guided and controlled radiotherapy. , 2014, Seminars in radiation oncology.

[26]  David Djajaputra,et al.  Real-time 3D surface-image-guided beam setup in radiotherapy of breast cancer. , 2004, Medical physics.

[27]  Jenghwa Chang,et al.  Accuracy and feasibility of cone-beam computed tomography for stereotactic radiosurgery setup. , 2007, Medical physics.

[28]  Lei Dong,et al.  Use of portal images and BAT ultrasonography to measure setup error and organ motion for prostate IMRT: implications for treatment margins. , 2003, International journal of radiation oncology, biology, physics.

[29]  Matthias Guckenberger,et al.  Potential of image-guidance, gating and real-time tracking to improve accuracy in pulmonary stereotactic body radiotherapy. , 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[30]  J. Chavaudra,et al.  Prescribing, Recording, And Reporting Photon Beam Therapy Presentation Of The ICRU Report # 50 , 1992 .

[31]  Steve B. Jiang,et al.  Fluoroscopic tracking of multiple implanted fiducial markers using multiple object tracking , 2007, Physics in medicine and biology.

[32]  M. V. van Herk,et al.  Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy. , 2002, International journal of radiation oncology, biology, physics.

[33]  C. Lawton,et al.  Stereotactic body radiotherapy for localized prostate cancer: interim results of a prospective phase II clinical trial , 2010 .

[34]  Steve B. Jiang,et al.  Frame-less and mask-less cranial stereotactic radiosurgery: a feasibility study , 2010, Physics in medicine and biology.

[35]  Lech Papiez,et al.  Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[36]  Paul J Keall,et al.  Megavoltage image-based dynamic multileaf collimator tracking of a NiTi stent in porcine lungs on a linear accelerator. , 2012, International journal of radiation oncology, biology, physics.

[37]  Matthias Guckenberger,et al.  Precision of Image-Guided Radiotherapy (IGRT) in Six Degrees of Freedom and Limitations in Clinical Practice , 2007, Strahlentherapie und Onkologie.

[38]  Wei Lu,et al.  Assessment of intrafraction mediastinal and hilar lymph node movement and comparison to lung tumor motion using four-dimensional CT. , 2007, International journal of radiation oncology, biology, physics.

[39]  Steve B. Jiang,et al.  Fluoroscopic tumor tracking for image-guided lung cancer radiotherapy , 2009, Physics in medicine and biology.

[40]  Geoffrey Hugo,et al.  Image-guided radiotherapy via daily online cone-beam CT substantially reduces margin requirements for stereotactic lung radiotherapy. , 2007, International journal of radiation oncology, biology, physics.

[41]  Richard Pötter,et al.  Dosimetric comparison of stereotactic body radiotherapy in different respiration conditions: a modeling study. , 2006, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[42]  C. Cleeland,et al.  Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure. , 2007, Journal of neurosurgery. Spine.

[43]  V. Budach,et al.  Image guided respiratory gated hypofractionated Stereotactic Body Radiation Therapy (H-SBRT) for liver and lung tumors: Initial experience , 2006, Acta oncologica.

[44]  Suresh Senan,et al.  Use of maximum intensity projections (MIP) for target volume generation in 4DCT scans for lung cancer. , 2005, International journal of radiation oncology, biology, physics.

[45]  J Yang,et al.  Evaluation of imaging performance of major image guidance systems , 2011, Biomedical imaging and intervention journal.

[46]  T. Guerrero,et al.  Acquiring 4D thoracic CT scans using a multislice helical method. , 2004, Physics in medicine and biology.

[47]  George T. Y. Chen,et al.  A phantom evaluation of a stereo-vision surface imaging system for radiotherapy patient setup. , 2005, Medical physics.

[48]  J. Mountz,et al.  Stereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: results of a phase I dose-escalation trial. , 2009, International journal of radiation oncology, biology, physics.

[49]  Geoffrey G. Zhang,et al.  Volumetric modulated arc planning for lung stereotactic body radiotherapy using conventional and unflattened photon beams: a dosimetric comparison with 3D technique , 2011, Radiation oncology.

[50]  Peter Balter,et al.  Implementation of feedback-guided voluntary breath-hold gating for cone beam CT-based stereotactic body radiotherapy. , 2011, International journal of radiation oncology, biology, physics.

[51]  Anton Mans,et al.  Volumetric-modulated arc therapy for stereotactic body radiotherapy of lung tumors: a comparison with intensity-modulated radiotherapy techniques. , 2011, International journal of radiation oncology, biology, physics.

[52]  Kathleen Malinowski,et al.  Fiducial-based translational localization accuracy of electromagnetic tracking system and on-board kilovoltage imaging system. , 2008, International journal of radiation oncology, biology, physics.

[53]  Tejinder Kataria,et al.  Image Guidance in Radiation Therapy: Techniques and Applications , 2014, Radiology research and practice.

[54]  Stephanie Frost,et al.  Extracranial stereotactic radioablation: results of a phase I study in medically inoperable stage I non-small cell lung cancer. , 2003, Chest.

[55]  W. O'Dell,et al.  Dose broadening due to target position variability during fractionated breath-held radiation therapy. , 2002, Medical physics.

[56]  F Lohr,et al.  Extracranial stereotactic radiation therapy: set-up accuracy of patients treated for liver metastases. , 2000, International journal of radiation oncology, biology, physics.

[57]  R K Ten Haken,et al.  The reproducibility of organ position using active breathing control (ABC) during liver radiotherapy. , 2001, International journal of radiation oncology, biology, physics.

[58]  Jan-Jakob Sonke,et al.  Frameless stereotactic body radiotherapy for lung cancer using four-dimensional cone beam CT guidance. , 2009, International journal of radiation oncology, biology, physics.

[59]  Kevin Cleary,et al.  Skin respiratory motion tracking for stereotactic radiosurgery using the CyberKnife , 2003, CARS.

[60]  D. Higginson,et al.  Stereotactic body radiotherapy (SBRT): Technological innovation and application in gynecologic oncology. , 2011, Gynecologic oncology.

[61]  Edward Clouser,et al.  Intensity-modulated radiotherapy-based stereotactic body radiotherapy for medically inoperable early-stage lung cancer: excellent local control. , 2010, International journal of radiation oncology, biology, physics.

[62]  Klaus Schilling,et al.  Tumor tracking and motion compensation with an adaptive tumor tracking system (ATTS): System description and prototype testing. , 2008, Medical physics.

[63]  Kenneth E Rosenzweig,et al.  Acute skin toxicity following stereotactic body radiation therapy for stage I non-small-cell lung cancer: who's at risk? , 2008, International journal of radiation oncology, biology, physics.

[64]  Robert D Timmerman,et al.  The North American Experience with Stereotactic Body Radiation Therapy in Non-small Cell Lung Cancer , 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[65]  Sanford L Meeks,et al.  Commissioning and quality assurance of an optically guided three-dimensional ultrasound target localization system for radiotherapy. , 2002, Medical physics.

[66]  Dong Han Lee,et al.  Stereotactic body radiotherapy for isolated paraaortic lymph node recurrence from colorectal cancer. , 2009, World journal of gastroenterology.

[67]  Jan-Jakob Sonke,et al.  Mid-ventilation CT scan construction from four-dimensional respiration-correlated CT scans for radiotherapy planning of lung cancer patients. , 2006, International journal of radiation oncology, biology, physics.

[68]  Francis Lilley,et al.  Opto-electronic sensing of body surface topology changes during radiotherapy for rectal cancer. , 2003, International journal of radiation oncology, biology, physics.

[69]  Hiroki Shirato,et al.  Stereotactic body radiotherapy (SBRT) for operable stage I non-small-cell lung cancer: can SBRT be comparable to surgery? , 2011, International journal of radiation oncology, biology, physics.

[70]  K. Kelly,et al.  A phase I/II trial of stereotactic body radiation therapy (SBRT) for lung metastases : Initial report of dose escalation and early toxicity , 2006 .

[71]  Riccardo Calandrino,et al.  Simultaneous tumour dose escalation and liver sparing in Stereotactic Body Radiation Therapy (SBRT) for liver tumours due to CTV-to-PTV margin reduction. , 2008, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[72]  I. Lax,et al.  Stereotactic radiotherapy of malignancies in the abdomen. Methodological aspects. , 1994, Acta oncologica.

[73]  George Starkschall,et al.  Dosimetric benefits of respiratory gating: a preliminary study , 2004, Journal of applied clinical medical physics.

[74]  Arthur L Boyer,et al.  Respiratory gated beam delivery cannot facilitate margin reduction, unless combined with respiratory correlated image guidance. , 2008, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[75]  Dwight E Heron,et al.  Stereotactic Body Radiotherapy in the Treatment of Advanced Adenocarcinoma of the Pancreas , 2011, American journal of clinical oncology.

[76]  John D Fenwick,et al.  Tomotherapy and other innovative IMRT delivery systems. , 2006, Seminars in radiation oncology.

[77]  C. Ling,et al.  Technical aspects of the deep inspiration breath-hold technique in the treatment of thoracic cancer. , 2000, International journal of radiation oncology, biology, physics.

[78]  Y. Rong,et al.  Improving Intra-Fractional Target Position Accuracy Using a 3D Surface Surrogate for Left Breast Irradiation Using the Respiratory-Gated Deep-Inspiration Breath-Hold Technique , 2014, PloS one.

[79]  Mitsuhiro Nakamura,et al.  Positional reproducibility of pancreatic tumors under end-exhalation breath-hold conditions using a visual feedback technique. , 2011, International journal of radiation oncology, biology, physics.

[80]  Martin J Murphy,et al.  Tracking moving organs in real time. , 2004, Seminars in radiation oncology.

[81]  Stuart Crozier,et al.  The Australian magnetic resonance imaging-linac program. , 2014, Seminars in radiation oncology.

[82]  Lei Dong,et al.  Experience of ultrasound-based daily prostate localization. , 2003, International journal of radiation oncology, biology, physics.

[83]  Ben Heijmen,et al.  Reduction of respiratory liver tumor motion by abdominal compression in stereotactic body frame, analyzed by tracking fiducial markers implanted in liver. , 2008, International journal of radiation oncology, biology, physics.

[84]  T E Schultheiss,et al.  A comparison of daily CT localization to a daily ultrasound-based system in prostate cancer. , 1999, International journal of radiation oncology, biology, physics.

[85]  Gabor Fichtinger,et al.  Monitoring tumor motion by real time 2D/3D registration during radiotherapy , 2012, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[86]  Geoffrey D. Hugo,et al.  Advances in 4D radiation therapy for managing respiration: part I - 4D imaging. , 2012, Zeitschrift fur medizinische Physik.

[87]  Samuel Ryu,et al.  American Society for Therapeutic Radiology and Oncology (ASTRO) and American College of Radiology (ACR) practice guideline for the performance of stereotactic body radiation therapy. , 2004, International journal of radiation oncology, biology, physics.

[88]  I. Lax,et al.  The role of radiotherapy in treatment of stage I non-small cell lung cancer. , 2003, Lung cancer.

[89]  Alan Pollack,et al.  Noninvasive Real-time Prostate Tracking Using a Transperineal Ultrasound Approach , 2012 .

[90]  Frieda Trichter,et al.  Prostate localization using transabdominal ultrasound imaging. , 2003, International journal of radiation oncology, biology, physics.

[91]  C. Enke,et al.  Prostate motion and isocenter adjustment from ultrasound-based localization during delivery of radiation therapy. , 2005, International journal of radiation oncology, biology, physics.

[92]  Derek Liu,et al.  An evaluation of the Clarity 3D ultrasound system for prostate localization , 2012, Journal of applied clinical medical physics.

[93]  E. Larsen,et al.  A method for incorporating organ motion due to breathing into 3D dose calculations. , 1999, Medical physics.

[94]  S. Kalnicki,et al.  CyberKnife Frameless Stereotactic Radiosurgery for Spinal Lesions: Clinical Experience in 125 Cases , 2004, Neurosurgery.

[95]  Robert D Timmerman,et al.  A phase I trial of stereotactic body radiation therapy (SBRT) for liver metastases. , 2005, International journal of radiation oncology, biology, physics.

[96]  CyberKnife Frameless Stereotactic Radiosurgery for Spinal Lesions: Clinical Experience in 125 Cases. , 2005, Neurosurgery.

[97]  Geoffrey G. Zhang,et al.  Four-dimensional computed tomography scan analysis of tumor and organ motion at varying levels of abdominal compression during stereotactic treatment of lung and liver. , 2008, International journal of radiation oncology, biology, physics.

[98]  Benjamin Movsas,et al.  A technique of quantitatively monitoring both respiratory and nonrespiratory motion in patients using external body markers. , 2007, Medical physics.

[99]  Fang-Fang Yin,et al.  Use of the BrainLAB ExacTrac X-Ray 6D system in image-guided radiotherapy. , 2008, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

[100]  R Jeraj,et al.  Monte Carlo study of a highly efficient gas ionization detector for megavoltage imaging and image-guided radiotherapy. , 2002, Medical physics.

[101]  D Ruan,et al.  Real-time profiling of respiratory motion: baseline drift, frequency variation and fundamental pattern change , 2009, Physics in medicine and biology.

[102]  M Kono,et al.  Intrafractional tumor position stability during computed tomography (CT)-guided frameless stereotactic radiation therapy for lung or liver cancers with a fusion of CT and linear accelerator (FOCAL) unit. , 2000, International journal of radiation oncology, biology, physics.

[103]  James Welsh,et al.  American Society for Therapeutic Radiology and Oncology and American College of Radiology practice guideline for the performance of stereotactic body radiation therapy. , 2004, International journal of radiation oncology, biology, physics.

[104]  Y. Ueda,et al.  Craniocaudal safety margin calculation based on interfractional changes in tumor motion in lung SBRT assessed with an EPID in cine mode. , 2012, International journal of radiation oncology, biology, physics.

[105]  U Oppitz,et al.  Stereotactic radiotherapy of extracranial targets: CT-simulation and accuracy of treatment in the stereotactic body frame. , 2000, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[106]  C. Ling,et al.  Respiration-correlated spiral CT: a method of measuring respiratory-induced anatomic motion for radiation treatment planning. , 2002, Medical physics.

[107]  F. Lohr,et al.  Noninvasive patient fixation for extracranial stereotactic radiotherapy. , 1999, International journal of radiation oncology, biology, physics.

[108]  T E Schultheiss,et al.  Ultrasound-based stereotactic guidance in prostate cancer--quantification of organ motion and set-up errors in external beam radiation therapy. , 2000, Computer aided surgery : official journal of the International Society for Computer Aided Surgery.

[109]  J. Bradley.  A review of radiation dose escalation trials for non-small cell lung cancer within the Radiation Therapy Oncology Group. , 2005, Seminars in oncology.

[110]  Gregory C Sharp,et al.  Integrated radiotherapy imaging system (IRIS): design considerations of tumour tracking with linac gantry-mounted diagnostic x-ray systems with flat-panel detectors , 2004, Physics in medicine and biology.

[111]  B. Fallone,et al.  The rotating biplanar linac-magnetic resonance imaging system. , 2014, Seminars in radiation oncology.

[112]  G. Christensen,et al.  A method for the reconstruction of four-dimensional synchronized CT scans acquired during free breathing. , 2003, Medical physics.

[113]  John Wong,et al.  Accuracy of a wireless localization system for radiotherapy. , 2005, International journal of radiation oncology, biology, physics.

[114]  T Kozuka,et al.  Lung cancer: intermittent irradiation synchronized with respiratory motion--results of a pilot study. , 1998, Radiology.

[115]  Timothy D. Solberg,et al.  Infrared patient positioning for stereotactic radiosurgery of extracranial tumors , 1999, Comput. Biol. Medicine.

[116]  E. Yorke,et al.  Deep inspiration breath hold and respiratory gating strategies for reducing organ motion in radiation treatment. , 2004, Seminars in radiation oncology.

[117]  S Nill,et al.  Standardized accuracy assessment of the calypso wireless transponder tracking system , 2014, Physics in medicine and biology.

[118]  H. Honda,et al.  Stereotactic radiotherapy for lung and liver tumors using a body cast system: setup accuracy and preliminary clinical outcome. , 2005, Radiation medicine.

[119]  Steve B. Jiang,et al.  Residual motion of lung tumours in gated radiotherapy with external respiratory surrogates , 2005, Physics in medicine and biology.

[120]  Masahiro Hiraoka,et al.  Clinical outcomes of a phase I/II study of 48 Gy of stereotactic body radiotherapy in 4 fractions for primary lung cancer using a stereotactic body frame. , 2005, International journal of radiation oncology, biology, physics.

[121]  T. Krieger,et al.  Stereotactic body radiotherapy for local boost irradiation in unfavourable locally recurrent gynaecological cancer. , 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[122]  Achim Schweikard,et al.  Respiration tracking in radiosurgery. , 2004, Medical physics.

[123]  Reto J. Bale,et al.  Reproducibility of Patient Positioning for Fractionated Extracranial Stereotactic Radiotherapy Using a Double-Vacuum Technique , 2004, Strahlentherapie und Onkologie.

[124]  Shinichi Shimizu,et al.  Three-dimensional intrafractional movement of prostate measured during real-time tumor-tracking radiotherapy in supine and prone treatment positions. , 2002, International journal of radiation oncology, biology, physics.

[125]  I. Barillot,et al.  Clinical assessment of the use of the Sonarray system for daily prostate localization. , 2006, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[126]  S. Ryu,et al.  Stereotactic body radiation therapy for primary, recurrent, and metastatic tumors in the head-and-neck region. , 2009, International journal of radiation oncology, biology, physics.

[127]  Matthias Guckenberger,et al.  Mid-ventilation concept for mobile pulmonary tumors: internal tumor trajectory versus selective reconstruction of four-dimensional computed tomography frames based on external breathing motion. , 2009, International journal of radiation oncology, biology, physics.

[128]  Steve B. Jiang,et al.  The management of imaging dose during image-guided radiotherapy: report of the AAPM Task Group 75. , 2007, Medical physics.

[129]  T Mizowaki,et al.  The effectiveness of an immobilization device in conformal radiotherapy for lung tumor: reduction of respiratory tumor movement and evaluation of the daily setup accuracy. , 2001, International journal of radiation oncology, biology, physics.

[130]  E Brian Butler,et al.  Versatility of the Novalis System to Deliver Image-Guided Stereotactic Body Radiation Therapy (SBRT) for Various Anatomical Sites , 2007, Technology in cancer research & treatment.

[131]  A. Nathan,et al.  Fabrication of Gd2O2S:Tb based phosphor films coupled with photodetectors for x-ray imaging applications , 2002 .

[132]  Koichi Yamazaki,et al.  Feasibility of insertion/implantation of 2.0-mm-diameter gold internal fiducial markers for precise setup and real-time tumor tracking in radiotherapy. , 2003, International journal of radiation oncology, biology, physics.

[133]  Lakshmi Santanam,et al.  Quality assurance for nonradiographic radiotherapy localization and positioning systems: report of Task Group 147. , 2012, Medical physics.

[134]  Steve B. Jiang,et al.  The management of respiratory motion in radiation oncology report of AAPM Task Group 76. , 2006, Medical physics.

[135]  A. Brahme,et al.  4D laser camera for accurate patient positioning, collision avoidance, image fusion and adaptive approaches during diagnostic and therapeutic procedures. , 2008, Medical physics.

[136]  T. Landberg,et al.  What margins should be added to the clinical target volume in radiotherapy treatment planning for lung cancer? , 1998, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[137]  Aaron Fenster,et al.  Three-dimensional ultrasound imaging and its use in quantifying organ and pathology volumes , 2003, Analytical and bioanalytical chemistry.

[138]  S. J. Marshall,et al.  Human body 3D imaging by speckle texture projection photogrammetry , 2000 .

[139]  Warren Kilby,et al.  The effect of the Varian amorphous silicon electronic portal imaging device on exit skin dose. , 2003, Physics in medicine and biology.

[140]  Abraham Philip,et al.  Stereotactic Body Radiation Therapy (SBRT) for lung metastases , 2006, Acta oncologica.

[141]  F. Lohr,et al.  Stereotactic single-dose radiation therapy of liver tumors: results of a phase I/II trial. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[142]  M. Schell,et al.  Hypofractionated stereotactic body radiation therapy (SBRT) for limited hepatic metastases. , 2007, International journal of radiation oncology, biology, physics.

[143]  S. Jaywant,et al.  Immobilization in stereotactic radiotherapy: the head and neck localizer frame. , 2001, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

[144]  Peter C Levendag,et al.  Stereotactic body radiation therapy for primary and metastatic liver tumors: A single institution phase i-ii study , 2006, Acta oncologica.

[145]  E. Wallen,et al.  A simple algorithm to assess patient suitability for Calypso‐seed implantation for four‐dimensional prostate localization , 2009, Journal of applied clinical medical physics.

[146]  [Simple method of stereotactic radiotherapy without stereotactic body frame for extracranial tumors]. , 2001, Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica.

[147]  M. V. van Herk,et al.  Physical aspects of a real-time tumor-tracking system for gated radiotherapy. , 2000, International journal of radiation oncology, biology, physics.

[148]  J. Severinghaus,et al.  Regulation of respiration (first of three parts). , 1977, The New England journal of medicine.

[149]  S Richardson,et al.  The treatment of primary and metastatic renal cell carcinoma (RCC) with image-guided stereotactic body radiation therapy (SBRT) , 2007, Biomedical imaging and intervention journal.

[150]  Eric Strom,et al.  Ultrasound-based localization. , 2005, Seminars in radiation oncology.

[151]  Jan Nyman,et al.  Outcome in a prospective phase II trial of medically inoperable stage I non-small-cell lung cancer patients treated with stereotactic body radiotherapy. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[152]  S. Lo,et al.  Diagnosis and treatment options including stereotactic body radiation therapy (SBRT) for adrenal metastases , 2012, Journal of Radiation Oncology.

[153]  Koichi Yamazaki,et al.  Real‐time tumor‐tracking radiation therapy for lung carcinoma by the aid of insertion of a gold marker using bronchofiberscopy , 2002, Cancer.

[154]  F. Wenz,et al.  A novel surface imaging system for patient positioning and surveillance during radiotherapy , 2013, Strahlentherapie und Onkologie.

[155]  Patrick A Kupelian,et al.  Real-time tumor tracking in the lung using an electromagnetic tracking system. , 2013, International journal of radiation oncology, biology, physics.

[156]  Masoom A. Haider,et al.  Comparison of liver tumor motion with and without abdominal compression using cine-magnetic resonance imaging. , 2011, International journal of radiation oncology, biology, physics.

[157]  Quynh-Thu Le,et al.  Results of a Phase I Dose-Escalation Study Using Single-Fraction Stereotactic Radiotherapy for Lung Tumors , 2006, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[158]  M. Hoogeman,et al.  Clinical accuracy of the respiratory tumor tracking system of the cyberknife: assessment by analysis of log files. , 2009, International journal of radiation oncology, biology, physics.