High-resolution EEG: modeling time, space and phase of SEPs following upper limb stimulation

Abstract High-resolution electroencephalography (HREEG) includes an elevated spatial sampling of scalp potentials (to 128 channels) and the reduction of head volume conduction effects by surface Laplacian transformation over (un)realistic head models. The HREEG has a high temporal resolution (in ms) and an acceptable spatial resolution (in cm) in the estimation of both radially and tangentially oriented cortical sources. This allows the modeling of short-term cortical responses evoked by median nerve stimulation based on phase-locked somatosensory-evoked potentials (SEPs). Phase-locked SEPs have the whole (ms) temporal resolution of EEG data, compared to the temporal resolution of nonphase-locked EEG oscillatory reactivity (i.e. about 100 ms for alpha rhythm, 8–12 Hz). In this report, the HREEG (128 channels) modeled temporal, spatial and phase-locked features of SEPs during sensorimotor interactions.

[1]  J E Desmedt,et al.  Bit-mapped color imaging of human evoked potentials with reference to the N20, P22, P27 and N30 somatosensory responses. , 1987, Electroencephalography and clinical neurophysiology.

[2]  S C Gandevia,et al.  Interfering cutaneous stimulation and the muscle afferent contribution to cortical potentials. , 1988, Electroencephalography and clinical neurophysiology.

[3]  Stephen J. Jones,et al.  Potentials evoked in human and monkey cerebral cortex by stimulation of the median nerve. A review of scalp and intracranial recordings. , 1991, Brain : a journal of neurology.

[4]  G Cheron,et al.  Specific gating of the early somatosensory evoked potentials during active movement. , 1987, Electroencephalography and clinical neurophysiology.

[5]  P. Rossini,et al.  Topography of spatially enhanced human shortlatency somatosensory evoked potentials , 1997, Neuroreport.

[6]  M. Wagner,et al.  N30 and the effect of explorative finger movements: a model of the contribution of the motor cortex to early somatosensory potentials , 1999, Clinical Neurophysiology.

[7]  Febo Cincotti,et al.  Spatial enhancement of EEG data by surface Laplacian estimation: the use of magnetic resonance imaging-based head models , 2001, Clinical Neurophysiology.

[8]  Claudio Babiloni,et al.  “Gating” of human short-latency somatosensory evoked cortical responses during execution of movement. A high resolution electroencephalography study , 1999, Brain Research.

[9]  A. Urbano,et al.  Spline Laplacian estimate of EEG potentials over a realistic magnetic resonance-constructed scalp surface model. , 1996, Electroencephalography and clinical neurophysiology.