Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction
暂无分享,去创建一个
Paul A. Townsend | Michael P. Lisanti | F. Sotgia | M. Lisanti | P. Townsend | R. Pestell | U. Martinez-outschoorn | B. Ózsvári | Duncan L Smith | A. Howell | H. Harrison | R. Lamb | Thomas Jackson | Rebecca Lamb | Hannah Harrison | Duncan L. Smith | Thomas Jackson | Bela Ozsvari | Ubaldo E. Martinez-Outschoorn | Richard G. Pestell | Anthony Howell | Federica Sotgia
[1] D. Ruggero. The role of Myc-induced protein synthesis in cancer. , 2009, Cancer research.
[2] N. Lee,et al. Identification of c-myc responsive genes using rat cDNA microarray. , 2000, Cancer research.
[3] C. Proud. mTOR Signalling in Health and Disease. , 2011, Biochemical Society transactions.
[4] R. Hoffman,et al. Human tumors are methionine dependent in vivo. , 1995, Anticancer research.
[5] S. Baylin,et al. Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance. , 2014, Molecular cell.
[6] R. Pearson,et al. Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k , 1997, The EMBO journal.
[7] J. Kopchick,et al. Growth hormone signaling is necessary for lifespan extension by dietary methionine , 2014, Aging cell.
[8] N. Mendell,et al. Intensive lifestyle changes may affect the progression of prostate cancer. , 2005, The Journal of urology.
[9] H. Scherthan,et al. Up-regulation of the embryonic self-renewal network through reversible polyploidy in irradiated p53-mutant tumour cells. , 2010, Experimental Cell Research.
[10] D. Nathans,et al. PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS: INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINS. , 1964, Proceedings of the National Academy of Sciences of the United States of America.
[11] N. Hagiwara,et al. Elimination of remaining undifferentiated induced pluripotent stem cells in the process of human cardiac cell sheet fabrication using a methionine-free culture condition. , 2015, Tissue engineering. Part C, Methods.
[12] M. Mccarty,et al. The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy. , 2009, Medical hypotheses.
[13] Danila Coradini,et al. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. , 2005, Cancer research.
[14] J. Rosen,et al. Stem cells in the etiology and treatment of cancer. , 2006, Current opinion in genetics & development.
[15] M. Todaro,et al. Therapeutic implications of cancer initiating cells , 2009, Expert opinion on biological therapy.
[16] C. Grandori,et al. Activation by c-Myc of transcription by RNA polymerases I, II and III. , 2006, Biochemical Society symposium.
[17] C. Proud. Cell signaling. mTOR, unleashed. , 2007, Science.
[18] A. D. Grey. Mitochondrial Free Radical Theory of Aging , 2021, Encyclopedia of Gerontology and Population Aging.
[19] D. Rowitch,et al. The metabolic defect of methionine dependence occurs frequently in human tumor cell lines. , 1983, Biochemical and biophysical research communications.
[20] W. Woodward,et al. Wnt/β-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line , 2007, Journal of Cell Science.
[21] P. Vogt. PI 3-kinase, mTOR, protein synthesis and cancer. , 2001, Trends in molecular medicine.
[22] L. Foster,et al. Evaluation of mTOR-regulated mRNA translation. , 2012, Methods in molecular biology.
[23] Christine C. Hudson,et al. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. , 1997, Science.
[24] H. Aburatani,et al. Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells. , 2014, Cell metabolism.
[25] P. Townsend,et al. DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells , 2013, Cell cycle.
[26] J. Ai,et al. Methionine and cystine double deprivation stress suppresses glioma proliferation via inducing ROS/autophagy. , 2015, Toxicology letters.
[27] D. Epner,et al. Nutrient Intake and Nutritional Indexes in Adults With Metastatic Cancer on a Phase I Clinical Trial of Dietary Methionine Restriction , 2002, Nutrition and cancer.
[28] M. Wahlqvist,et al. Cardiovascular Disease Mortality and Cancer Incidence in Vegetarians: A Meta-Analysis and Systematic Review , 2012, Annals of Nutrition and Metabolism.
[29] A. Szalay,et al. Biotherapeutic approaches to target cancer stem cells. , 2013, Journal of stem cells.
[30] N. Simone,et al. Nutrient restriction and radiation therapy for cancer treatment: when less is more. , 2013, The oncologist.
[31] M. Orlich,et al. Vegetarian dietary patterns and mortality in Adventist Health Study 2. , 2013, JAMA internal medicine.
[32] C. Proud,et al. The mTOR pathway in the control of protein synthesis. , 2006, Physiology.
[33] S. Snyder,et al. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[34] E. Lander,et al. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[35] Timothy Hunter,et al. Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer , 2009, Breast Cancer Research and Treatment.
[36] M. Dean. ABC Transporters, Drug Resistance, and Cancer Stem Cells , 2009, Journal of Mammary Gland Biology and Neoplasia.
[37] M. Quinn,et al. Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden , 2013, Molecular Cancer.
[38] R. Theuer. Effect of essential amino acid restriction on the growth of female C57BL mice and their implanted BW10232 adenocarcinomas. , 1971, The Journal of nutrition.
[39] C. Proud,et al. mTOR signaling regulates the processing of pre-rRNA in human cells , 2011, Nucleic acids research.
[40] T. Sugimura,et al. Quantitative nutritional studies with water-soluble, chemically defined diets. VIII. The forced feeding of diets each lacking in one essential amino acid. , 1959, Archives of biochemistry and biophysics.
[41] A. Tsirigos,et al. Mitochondria “fuel” breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells , 2012, Cell cycle.
[42] P. Booth,et al. Biochemical Society Symposium , 2005 .
[43] R. Eisenman,et al. c-Myc enhances protein synthesis and cell size during B lymphocyte development. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[44] T. Hunter,et al. Oncogenic kinase signalling , 2001, Nature.
[45] Mark W. Dewhirst,et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response , 2006, Nature.
[46] F. Clavel-Chapelon,et al. Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition , 2013, BMC Medicine.
[47] B. Amati,et al. Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis. , 2000, Nucleic acids research.
[48] R. Clarke,et al. A Detailed Mammosphere Assay Protocol for the Quantification of Breast Stem Cell Activity , 2012, Journal of Mammary Gland Biology and Neoplasia.
[49] C. Proud,et al. When translation meets transformation: the mTOR story , 2006, Oncogene.
[50] Frank Pajonk,et al. The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. , 2006, Journal of the National Cancer Institute.
[51] R. Smith,et al. The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture. , 1974, Proceedings of the National Academy of Sciences of the United States of America.
[52] W. Cao,et al. Methionine-dependence and combination chemotherapy on human gastric cancer cells in vitro. , 2002, World journal of gastroenterology.
[53] C. Proud. mTOR, Unleashed , 2007, Science.
[54] G. Barja,et al. Regulation of longevity and oxidative stress by nutritional interventions: Role of methionine restriction , 2013, Experimental Gerontology.
[55] Charlotte Kuperwasser,et al. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy , 2008, Breast Cancer Research.
[56] N. Mabbott,et al. Progress in Molecular Biology and Translational Science , 2017 .
[57] Davide Ruggero,et al. Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency , 2008, Nature.
[58] R. Sinha,et al. Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice , 2014, The Prostate.
[59] Z. Miao,et al. Multi-drug-resistant cells enriched from chronic myeloid leukemia cells by Doxorubicin possess tumor-initiating-cell properties. , 2013, Journal of pharmacological sciences.
[60] B. Dutrillaux,et al. Methionine depletion enhances the antitumoral efficacy of cytotoxic agents in drug-resistant human tumor xenografts. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[61] S. Lyle,et al. Quiescent, Slow-Cycling Stem Cell Populations in Cancer: A Review of the Evidence and Discussion of Significance , 2010, Journal of oncology.
[62] E. Lagasse,et al. Cancerous stem cells: deviant stem cells with cancer-causing misbehavior , 2010, Stem Cell Research & Therapy.
[63] Kathryn A. O’Donnell,et al. The c-Myc target gene network. , 2006, Seminars in cancer biology.
[64] Philippe P Roux,et al. Translational control by oncogenic signaling pathways. , 2015, Biochimica et biophysica acta.
[65] V. Anisimov,et al. Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin , 2014, Cancer biology & therapy.
[66] F. Johnson,et al. Methionine Restriction Activates the Retrograde Response and Confers Both Stress Tolerance and Lifespan Extension to Yeast, Mouse and Human Cells , 2014, PloS one.
[67] G. Barja. The mitochondrial free radical theory of aging. , 2014, Progress in molecular biology and translational science.
[68] F. Sotgia,et al. Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug. , 2012, The American journal of pathology.
[69] E. Lagasse,et al. Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1 , 2013, Oncotarget.
[70] James B. Mitchell,et al. Caloric restriction augments radiation efficacy in breast cancer , 2013, Cell cycle.
[71] Alex Groce,et al. Therapeutic tumor-specific cell cycle block induced by methionine starvation in vivo. , 1993, Cancer research.
[72] R. Wiesner,et al. Methionine restriction slows down senescence in human diploid fibroblasts , 2014, Aging cell.
[73] M. Fenech,et al. A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension. , 2012, Cancer treatment reviews.
[74] F. Sotgia,et al. Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition , 2014, Oncotarget.
[75] M. Poupon,et al. Decreased rat rhabdomyosarcoma pulmonary metastases in response to a low methionine diet. , 1987, Anticancer research.
[76] MatsuuraKatsuhisa,et al. Elimination of Remaining Undifferentiated Induced Pluripotent Stem Cells in the Process of Human Cardiac Cell Sheet Fabrication Using a Methionine-Free Culture Condition , 2015 .
[77] P. Panda,et al. Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer. , 2013, Oral oncology.
[78] C. Proud,et al. Amino acids and mTOR signalling in anabolic function. , 2007, Biochemical Society transactions.