Intracellular Staphylococcus aureus persisters upon antibiotic exposure

[1]  B. Conlon,et al.  Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection , 2019, Nature Microbiology.

[2]  Namiko Mitarai,et al.  Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells , 2019, Scientific Reports.

[3]  C. Wolz,et al.  Inactivation of TCA cycle enhances Staphylococcus aureus persister cell formation in stationary phase , 2018, Scientific Reports.

[4]  Tanel Tenson,et al.  Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells , 2018, mBio.

[5]  P. Tulkens,et al.  Cellular Pharmacokinetics and Intracellular Activity of Gepotidacin against Staphylococcus aureus Isolates with Different Resistance Phenotypes in Models of Cultured Phagocytic Cells , 2018, Antimicrobial Agents and Chemotherapy.

[6]  M. Sørensen,et al.  Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells , 2017, mBio.

[7]  M. Fraunholz,et al.  Inside job: Staphylococcus aureus host-pathogen interactions. , 2017, International journal of medical microbiology : IJMM.

[8]  Thomas Cokelaer,et al.  'Sequana': a Set of Snakemake NGS pipelines , 2017, J. Open Source Softw..

[9]  A. Charbit,et al.  Intracellular Survival of Staphylococcus aureus in Endothelial Cells: A Matter of Growth or Persistence , 2017, Front. Microbiol..

[10]  R. Fisher,et al.  Persistent bacterial infections and persister cells , 2017, Nature Reviews Microbiology.

[11]  Robert Powers,et al.  Amino Acid Catabolism in Staphylococcus aureus and the Function of Carbon Catabolite Repression , 2017, mBio.

[12]  R. Santhosh,et al.  What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin–Antitoxin Systems and Persistence? , 2016, Front. Microbiol..

[13]  Matthias Heinemann,et al.  Molecular Systems Biology Peer Review Process File Bacterial Persistence Is an Active Σ S Stress Response to Metabolic Flux Limitation Transaction Report , 2022 .

[14]  Ofer Fridman,et al.  Distinguishing between resistance, tolerance and persistence to antibiotic treatment , 2016, Nature Reviews Microbiology.

[15]  S. Foster,et al.  Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages , 2015, Cellular microbiology.

[16]  Stephanie M. Amato,et al.  Persister Heterogeneity Arising from a Single Metabolic Stress , 2015, Current Biology.

[17]  Tanel Tenson,et al.  Recent functional insights into the role of (p)ppGpp in bacterial physiology , 2015, Nature Reviews Microbiology.

[18]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[19]  P. E. Granum,et al.  Staphylococcus aureus competence genes: mapping of the SigH, ComK1 and ComK2 regulons by transcriptome sequencing , 2014, Molecular microbiology.

[20]  David W. Schryer,et al.  The general mode of translation inhibition by macrolide antibiotics , 2014, Proceedings of the National Academy of Sciences.

[21]  B. Conlon,et al.  Staphylococcus aureus chronic and relapsing infections: Evidence of a role for persister cells , 2014, BioEssays : news and reviews in molecular, cellular and developmental biology.

[22]  N. Reiling,et al.  Isolation of Human Monocytes by Double Gradient Centrifugation and Their Differentiation to Macrophages in Teflon-coated Cell Culture Bags , 2014, Journal of visualized experiments : JoVE.

[23]  K. Gerdes,et al.  Molecular Mechanisms Underlying Bacterial Persisters , 2014, Cell.

[24]  G. Reid,et al.  Selective Target Inactivation Rather than Global Metabolic Dormancy Causes Antibiotic Tolerance in Uropathogens , 2014, Antimicrobial Agents and Chemotherapy.

[25]  David W. Holden,et al.  Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters , 2014, Science.

[26]  C. Wolz,et al.  Two Small (p)ppGpp Synthases in Staphylococcus aureus Mediate Tolerance against Cell Envelope Stress Conditions , 2013, Journal of bacteriology.

[27]  Thomas K. Wood,et al.  Bacterial Persister Cell Formation and Dormancy , 2013, Applied and Environmental Microbiology.

[28]  J. Collins,et al.  Microbial persistence and the road to drug resistance. , 2013, Cell host & microbe.

[29]  Wei Shi,et al.  featureCounts: an efficient general purpose program for assigning sequence reads to genomic features , 2013, Bioinform..

[30]  Mehmet A. Orman,et al.  Dormancy Is Not Necessary or Sufficient for Bacterial Persistence , 2013, Antimicrobial Agents and Chemotherapy.

[31]  P. François,et al.  The Stringent Response of Staphylococcus aureus and Its Impact on Survival after Phagocytosis through the Induction of Intracellular PSMs Expression , 2012, PLoS pathogens.

[32]  Anchal Singh,et al.  An insight into the significance of the DnaK heat shock system in Staphylococcus aureus. , 2012, International journal of medical microbiology : IJMM.

[33]  P. François,et al.  Global Analysis of the Staphylococcus aureus Response to Mupirocin , 2011, Antimicrobial Agents and Chemotherapy.

[34]  F. Lépine,et al.  Active Starvation Responses Mediate Antibiotic Tolerance in Biofilms and Nutrient-Limited Bacteria , 2011, Science.

[35]  F. Vandenesch,et al.  A novel flow cytometry-based assay for the quantification of Staphylococcus aureus adhesion to and invasion of eukaryotic cells. , 2011, Journal of microbiological methods.

[36]  Clinton C. Dawson,et al.  “Persisters”: Survival at the Cellular Level , 2011, PLoS pathogens.

[37]  Jan Michiels,et al.  Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies. , 2011, Journal of medical microbiology.

[38]  Marcel Martin Cutadapt removes adapter sequences from high-throughput sequencing reads , 2011 .

[39]  L. Ramakrishnan,et al.  Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism , 2011, Cell.

[40]  P. Tulkens,et al.  Activity of moxifloxacin against intracellular community-acquired methicillin-resistant Staphylococcus aureus: comparison with clindamycin, linezolid and co-trimoxazole and attempt at defining an intracellular susceptibility breakpoint. , 2011, The Journal of antimicrobial chemotherapy.

[41]  W. Kelley,et al.  Return of the Trojan horse: intracellular phenotype switching and immune evasion by Staphylococcus aureus , 2011, EMBO molecular medicine.

[42]  H. Šanderová,et al.  Rapid changes in gene expression: DNA determinants of promoter regulation by the concentration of the transcription initiating NTP in Bacillus subtilis , 2011, Nucleic acids research.

[43]  N. McCallum,et al.  Induction kinetics of the Staphylococcus aureus cell wall stress stimulon in response to different cell wall active antibiotics , 2011, BMC Microbiology.

[44]  S. Lory,et al.  Emergence of Pseudomonas aeruginosa Strains Producing High Levels of Persister Cells in Patients with Cystic Fibrosis , 2010, Journal of bacteriology.

[45]  M. K. Kadowaki,et al.  DnaK and GroEL are induced in response to antibiotic and heat shock in Acinetobacter baumannii. , 2010, Journal of medical microbiology.

[46]  J. Mckinney,et al.  Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice , 2010, Proceedings of the National Academy of Sciences.

[47]  J. Collins,et al.  How antibiotics kill bacteria: from targets to networks , 2010, Nature Reviews Microbiology.

[48]  Manuel Liebeke,et al.  Role of the (p)ppGpp Synthase RSH, a RelA/SpoT Homolog, in Stringent Response and Virulence of Staphylococcus aureus , 2010, Infection and Immunity.

[49]  Jessica A. Thompson,et al.  Dynamics of intracellular bacterial replication at the single cell level , 2010, Proceedings of the National Academy of Sciences.

[50]  M. Vulić,et al.  SOS Response Induces Persistence to Fluoroquinolones in Escherichia coli , 2009, PLoS genetics.

[51]  Cole Trapnell,et al.  Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.

[52]  Xilin Zhao,et al.  Contribution of Oxidative Damage to Antimicrobial Lethality , 2009, Antimicrobial Agents and Chemotherapy.

[53]  J. Davies,et al.  Effects of Subinhibitory Concentrations of Antibiotics on SOS and DNA Repair Gene Expression in Staphylococcus aureus , 2008, Antimicrobial Agents and Chemotherapy.

[54]  Tanel Tenson,et al.  Cell division in Escherichia coli cultures monitored at single cell resolution , 2008, BMC Microbiology.

[55]  Eric P. Skaar,et al.  Neutrophil Microbicides Induce a Pathogen Survival Response in Community-Associated Methicillin-Resistant Staphylococcus aureus1 , 2008, The Journal of Immunology.

[56]  R. Jayaswal,et al.  Role for dnaK locus in tolerance of multiple stresses in Staphylococcus aureus. , 2007, Microbiology.

[57]  A. Tomasz,et al.  Extensive and Genome-Wide Changes in the Transcription Profile of Staphylococcus aureus Induced by Modulating the Transcription of the Cell Wall Synthesis Gene murF , 2006, Journal of bacteriology.

[58]  S. Peterson,et al.  Complete and SOS-Mediated Response of Staphylococcus aureus to the Antibiotic Ciprofloxacin , 2006, Journal of bacteriology.

[59]  R. Overbeek,et al.  Characterization of the Staphylococcus aureus Heat Shock, Cold Shock, Stringent, and SOS Responses and Their Effects on Log-Phase mRNA Turnover , 2006, Journal of bacteriology.

[60]  U. Varshney,et al.  Peptidyl-tRNA hydrolase and its critical role in protein biosynthesis. , 2006, Microbiology.

[61]  P. Tulkens,et al.  Pharmacodynamic Evaluation of the Intracellular Activities of Antibiotics against Staphylococcus aureus in a Model of THP-1 Macrophages , 2006, Antimicrobial Agents and Chemotherapy.

[62]  Dong-Eun Chang,et al.  Guanosine 3′,5′-bispyrophosphate coordinates global gene expression during glucose-lactose diauxie in Escherichia coli , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[63]  Adeline R. Whitney,et al.  Insights into Mechanisms Used by Staphylococcus aureus to Avoid Destruction by Human Neutrophils1 , 2005, The Journal of Immunology.

[64]  T. Raivio Faculty Opinions recommendation of SOS response induction by beta-lactams and bacterial defense against antibiotic lethality. , 2004 .

[65]  S. Leibler,et al.  Bacterial Persistence as a Phenotypic Switch , 2004, Science.

[66]  Stanley N Cohen,et al.  SOS Response Induction by ß-Lactams and Bacterial Defense Against Antibiotic Lethality , 2004, Science.

[67]  V. Singh,et al.  Genome-wide transcriptional profiling of the response of Staphylococcus aureus to cell-wall-active antibiotics reveals a cell-wall-stress stimulon. , 2003, Microbiology.

[68]  Måns Ehrenberg,et al.  The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. , 2003, Journal of molecular biology.

[69]  P. Tulkens,et al.  Quantitative Analysis of Gentamicin, Azithromycin, Telithromycin, Ciprofloxacin, Moxifloxacin, and Oritavancin (LY333328) Activities against Intracellular Staphylococcus aureus in Mouse J774 Macrophages , 2003, Antimicrobial Agents and Chemotherapy.

[70]  S. Foster,et al.  σB Modulates Virulence Determinant Expression and Stress Resistance: Characterization of a Functional rsbU Strain Derived from Staphylococcus aureus 8325-4 , 2002, Journal of bacteriology.

[71]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[72]  M. Palma,et al.  Evaluation of a Tetracycline-Inducible Promoter inStaphylococcus aureus In Vitro and In Vivo and Its Application in Demonstrating the Role of sigB in Microcolony Formation , 2001, Infection and Immunity.

[73]  B. D. Davis Mechanism of Bactericidal Action of Aminoglycosides , 1987, Microbiological reviews.

[74]  B. D. Davis Mechanism of bactericidal action of aminoglycosides , 1987, Microbiological reviews.

[75]  R. Snyderman,et al.  Biologic and biochemical activities of continuous macrophage cell lines P388D1 and J774.1. , 1977, Journal of immunology.

[76]  J. Bigger TREATMENT OF STAPHYLOCOCCAL INFECTIONS WITH PENICILLIN BY INTERMITTENT STERILISATION , 1944 .

[77]  J. Adkins,et al.  Persister formation in Staphylococcus aureus is associated with ATP depletion. , 2016, Nature microbiology.

[78]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[79]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .