Reduced kappa-opioid activity in a rat model of cholestasis.

[1]  Ulrike Holzgrabe,et al.  Comparison of Pharmacological Activities of Three Distinct κ Ligands (Salvinorin A, TRK-820 and 3FLB) on κ Opioid Receptors in Vitro and Their Antipruritic and Antinociceptive Activities in Vivo , 2005, Journal of Pharmacology and Experimental Therapeutics.

[2]  H. Nagase,et al.  Inhibitory effects of TRK-820 on systemic skin scratching induced by morphine in rhesus monkeys. , 2004, Life sciences.

[3]  A. Cowan,et al.  Kappa opioid agonists suppress chloroquine-induced scratching in mice. , 2004, European journal of pharmacology.

[4]  M. Greaves,et al.  Itch: More than Skin Deep , 2004, International Archives of Allergy and Immunology.

[5]  N. Bergasa Pruritus in chronic liver disease: Mechanisms and treatment , 2004, Current gastroenterology reports.

[6]  J. Traynor,et al.  The [35S]GTPγS binding assay: approaches and applications in pharmacology , 2003 .

[7]  H. Mosberg,et al.  Activation of κ-Opioid Receptors Inhibits Pruritus Evoked by Subcutaneous or Intrathecal Administration of Morphine in Monkeys , 2003, Journal of Pharmacology and Experimental Therapeutics.

[8]  M. Niculescu,et al.  Cocaine alters mu but not delta or kappa opioid receptor‐stimulated in situ [35S]GTPγS binding in rat brain , 2003, Synapse.

[9]  J. Neuberger,et al.  Opiate antagonist therapy for the pruritus of cholestasis: the avoidance of opioid withdrawal-like reactions. , 2002, QJM : monthly journal of the Association of Physicians.

[10]  J. Kamei,et al.  Antipruritic activity of the κ-opioid receptor agonist, TRK-820 , 2002 .

[11]  B. Gulyás,et al.  An overview on functional receptor autoradiography using [35S]GTPγS , 2001, Brain Research Reviews.

[12]  M. Ko,et al.  An Experimental Itch Model in Monkeys: Characterization of Intrathecal Morphine-induced Scratching and Antinociception , 2000, Anesthesiology.

[13]  H. Meltzer,et al.  Selective Increases in Phosphoinositide Signaling Activity and G Protein Levels in Postmortem Brain from Subjects with Schizophrenia or Alcohol Dependence , 1998, Journal of neurochemistry.

[14]  S. Childers,et al.  Anatomical distribution of mu, delta, and kappa opioid‐ and nociceptin/orphanin FQ‐stimulated [35S]Guanylyl‐5′‐O‐(γ‐Thio)‐triphosphate binding in guinea pig brain , 1997, The Journal of comparative neurology.

[15]  G. Celesia,et al.  Regional alterations in M1 muscarinic receptor-G protein coupling in Alzheimer's disease. , 1995, Journal of neuropathology and experimental neurology.

[16]  D. Selley,et al.  In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[17]  W. Young,et al.  Cholestasis is associated with preproenkephalin mRNA expression in the adult rat liver. , 1995, The American journal of physiology.

[18]  N. Bergasa,et al.  Endogenous opioids accumulate in plasma in a rat model of acute cholestasis. , 1992, Gastroenterology.

[19]  N. Bergasa,et al.  Central mu-opioid receptors are down-regulated in a rat model of cholestasis. , 1992, Journal of hepatology.

[20]  G. Vauquelin,et al.  Coupling of D1 dopamine receptors to the guanine nucleotide binding protein Gs is deficient in Huntington's disease , 1989, Brain Research.

[21]  J. Szepietowski,et al.  Itch: scratching more than the surface. , 2003, QJM : monthly journal of the Association of Physicians.

[22]  D. Alling,et al.  Cholestasis in the male rat is associated with naloxone-reversible antinociception. , 1994, Journal of hepatology.

[23]  M. Turner,et al.  Plasma from patients with the pruritus of cholestasis induces opioid receptor-mediated scratching in monkeys. , 1993, Life sciences.