BMP 9 / COX-2 axial mediates high phosphate-induced calcification in vascular smooth muscle cells via Wnt / β-catenin pathway † Running title : BMP 9 / COX-2 and vascular smooth muscle cells calcification

1 Department of Nephrology, First Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China 2 Key Laboratory for Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing, People’s Republic of China, 400016 3 Department of pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing, People’s Republic of China, 400016 4 Infectious Disease Laboratory of Chongqing Medical University, Chongqing, People’s Republic of China 5 Department of orthorpedic, Second Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China 6 Department of orthorpedic, Children Hospital of Chongqing Medical University, Chongqing, People’s Republic of China

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