Identification of niclosamide as a novel antiviral agent against porcine epidemic diarrhea virus infection by targeting viral internalization
暂无分享,去创建一个
Wentao Li | Panpan Qin | Wenjuan Du | Shuai Li | Dongliang Li | Yue Wang | Chenxu Zhao | Yongtao Li | Ya-Qian Li | Huimin Huang | Xia Yang
[1] A. Fabro,et al. Identification of immunomodulatory drugs that inhibit multiple inflammasomes and impair SARS-CoV-2 infection , 2022, Science advances.
[2] Xiaoting Wang,et al. Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus In Vitro and In Vivo , 2022, Viruses.
[3] J. Julien,et al. Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells , 2022, bioRxiv.
[4] Gaiping Zhang,et al. The tyrosine phosphatase PTPN14 inhibits the activation of STAT3 in PEDV infected Vero cells. , 2022, Veterinary microbiology.
[5] P. Auewarakul,et al. Synergistic anti-SARS-CoV-2 activity of repurposed anti-parasitic drug combinations , 2021, BMC pharmacology & toxicology.
[6] Morten O. A. Sommer,et al. Niclosamide—A promising treatment for COVID‐19 , 2021, British journal of pharmacology.
[7] B. Hoen,et al. Niclosamide shows strong antiviral activity in a human airway model of SARS-CoV-2 infection and a conserved potency against the Alpha (B.1.1.7), Beta (B.1.351) and Delta variant (B.1.617.2) , 2021, PloS one.
[8] M. Peppelenbosch,et al. Niclosamide inhibits hepatitis E virus through suppression of NF-kappaB signalling. , 2021, Antiviral research.
[9] W. Bao,et al. miR-129a-3p Inhibits PEDV Replication by Targeting the EDA-Mediated NF-κB Pathway in IPEC-J2 Cells , 2021, International journal of molecular sciences.
[10] C. Conrad,et al. SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals , 2021, Nature Communications.
[11] M. Giacca,et al. Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia , 2021, Nature.
[12] B. Baradaran,et al. The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV , 2021, Archives of virology.
[13] Thomas S van Zanten,et al. Niclosamide inhibits SARS-CoV2 entry by blocking internalization through pH-dependent CLIC/GEEC endocytic pathway , 2020, bioRxiv.
[14] Dennis Brown,et al. The H+-ATPase (V-ATPase): from proton pump to signaling complex in health and disease , 2020, American journal of physiology. Cell physiology.
[15] T. Mak,et al. An aberrant STAT pathway is central to COVID-19 , 2020, Cell Death & Differentiation.
[16] Xiufan Liu,et al. Inhibition of porcine epidemic diarrhea virus (PEDV) replication by A77 1726 through targeting JAK and Src tyrosine kinases , 2020, Virology.
[17] Qiuhong Wang,et al. Porcine epidemic diarrhea virus (PEDV): An update on etiology, transmission, pathogenesis, and prevention and control , 2020, Virus Research.
[18] Shalini Sharma,et al. Host-Directed Antiviral Therapy , 2020, Clinical Microbiology Reviews.
[19] K. He,et al. Nonstructural protein 6 of porcine epidemic diarrhea virus induces autophagy to promote viral replication via the PI3K/Akt/mTOR axis , 2020, Veterinary Microbiology.
[20] David Shum,et al. Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs , 2020, Antimicrobial Agents and Chemotherapy.
[21] Jia Zhou,et al. Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential , 2020, ACS infectious diseases.
[22] Yongchang Cao,et al. PEDV enters cells through clathrin-, caveolae-, and lipid raft-mediated endocytosis and traffics via the endo-/lysosome pathway , 2020, Veterinary Research.
[23] M. Marsh,et al. Targeting viral entry as a strategy for broad-spectrum antivirals , 2019, F1000Research.
[24] H. Yue,et al. Emergence of porcine epidemic diarrhea viruses with the novel S genes in Tibetan pigs in the Qinghai-Tibetan Plateau in China. , 2019, Virus research.
[25] Baek Kim,et al. Neutralization of Acidic Intracellular Vesicles by Niclosamide Inhibits Multiple Steps of the Dengue Virus Life Cycle In Vitro , 2019, Scientific Reports.
[26] R. Angell,et al. Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry , 2019, Viruses.
[27] Matthias Ernst,et al. Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map , 2018, Nature Reviews Cancer.
[28] Yuxin Wang,et al. A new STAT3 function: pH regulation , 2018, Cell Research.
[29] B. Liu,et al. STAT3 associates with vacuolar H+-ATPase and regulates cytosolic and lysosomal pH , 2018, Cell Research.
[30] Chiou-Feng Lin,et al. The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR , 2018, PLoS neglected tropical diseases.
[31] Xin Zhou,et al. STAT3 roles in viral infection: antiviral or proviral? , 2018, Future virology.
[32] Qiuhong Wang,et al. New variants of porcine epidemic diarrhea virus with large deletions in the spike protein, identified in the United States, 2016-2017 , 2018, Archives of Virology.
[33] Y. Mehellou,et al. Niclosamide, a Drug with Many (Re)purposes , 2018, ChemMedChem.
[34] Li Feng,et al. Porcine Epidemic Diarrhea Virus-Induced Epidermal Growth Factor Receptor Activation Impairs the Antiviral Activity of Type I Interferon , 2018, Journal of Virology.
[35] R. Premont,et al. Niclosamide: Beyond an antihelminthic drug , 2017, Cellular Signalling.
[36] Yanping Jiang,et al. TMPRSS2 and MSPL Facilitate Trypsin-Independent Porcine Epidemic Diarrhea Virus Replication in Vero Cells , 2017, Viruses.
[37] V. Gerdts,et al. Vaccines for porcine epidemic diarrhea virus and other swine coronaviruses , 2016, Veterinary Microbiology.
[38] Tzong-Yuan Wu,et al. Antiviral activities of niclosamide and nitazoxanide against chikungunya virus entry and transmission , 2016, Antiviral Research.
[39] Shibo Jiang,et al. Cell Entry of Porcine Epidemic Diarrhea Coronavirus Is Activated by Lysosomal Proteases* , 2016, The Journal of Biological Chemistry.
[40] Yudong Ren,et al. Porcine epidemic diarrhea virus infection induces NF-κB activation through the TLR2, TLR3 and TLR9 pathways in porcine intestinal epithelial cells. , 2015, The Journal of general virology.
[41] H. Moon,et al. Porcine epidemic diarrhea: a review of current epidemiology and available vaccines , 2015, Clinical and Experimental Vaccine Research.
[42] Gary R. Whittaker,et al. Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis , 2014, Virus Research.
[43] L. Pelkmans,et al. Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner , 2014, PLoS pathogens.
[44] Jung-Eun Park,et al. Clathrin- and serine proteases-dependent uptake of porcine epidemic diarrhea virus into Vero cells , 2014, Virus Research.
[45] Donald J Buchsbaum,et al. Multi-targeted therapy of cancer by niclosamide: A new application for an old drug. , 2014, Cancer letters.
[46] A. Aloia,et al. Signal transducer and activator of transcription 3 is a proviral host factor for hepatitis C virus , 2013, Hepatology.
[47] Li Fang,et al. Origin, Evolution, and Genotyping of Emergent Porcine Epidemic Diarrhea Virus Strains in the United States , 2013, mBio.
[48] K. Schwartz,et al. Emergence of Porcine epidemic diarrhea virus in the United States: clinical signs, lesions, and viral genomic sequences , 2013, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
[49] E. Chiocca,et al. STAT3 Activation Promotes Oncolytic HSV1 Replication in Glioma Cells , 2013, PloS one.
[50] R. Schwendener,et al. Niclosamide Is a Proton Carrier and Targets Acidic Endosomes with Broad Antiviral Effects , 2012, PLoS pathogens.
[51] Qigai He,et al. New Variants of Porcine Epidemic Diarrhea Virus, China, 2011 , 2012, Emerging infectious diseases.
[52] G. Whittaker,et al. Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein , 2012, Viruses.
[53] D. Smee,et al. Inhibition of Severe Acute Respiratory Syndrome Coronavirus Replication in a Lethal SARS-Cov Balb/C Mouse Model by Stinging Nettle Lectin, Urtica Dioica Agglutinin (UDA) , 2010, Antiviral Research.
[54] O. V. Sergeev. [Porcine epidemic diarrhea]. , 2009, Voprosy virusologii.
[55] E. Hurt,et al. Activation of signal transducer and activator of transcription 3 through a phosphomimetic serine 727 promotes prostate tumorigenesis independent of tyrosine 705 phosphorylation. , 2008, Cancer research.
[56] S. Harrison. Viral membrane fusion , 2008, Nature Structural &Molecular Biology.
[57] S. Morikawa,et al. Protease-mediated enhancement of severe acute respiratory syndrome coronavirus infection. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[58] H. Hsieh,et al. Inhibition of Severe Acute Respiratory Syndrome Coronavirus Replication by Niclosamide , 2004, Antimicrobial Agents and Chemotherapy.
[59] C. Wermuth. Selective optimization of side activities: another way for drug discovery. , 2004, Journal of medicinal chemistry.