Impact of cremophor-EL and polysorbate-80 on digoxin permeability across rat jejunum: delineation of thermodynamic and transporter related events using the reciprocal permeability approach.
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[1] E. Wang,et al. In vitro flow cytometry method to quantitatively assess inhibitors of P-glycoprotein. , 2000, Drug metabolism and disposition: the biological fate of chemicals.
[2] J. Beijnen,et al. MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid , 2005, International journal of cancer.
[3] J. Boyer,et al. ATP-dependent GSH and glutathione S-conjugate transport in skate liver: role of an Mrp functional homologue. , 2000, American journal of physiology. Gastrointestinal and liver physiology.
[4] B. Hirst,et al. Drug Absorption Limited by P-Glycoprotein-Mediated Secretory Drug Transport in Human Intestinal Epithelial Caco-2 Cell Layers , 1993, Pharmaceutical Research.
[5] B. Sankaran,et al. P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site (*) , 1995, The Journal of Biological Chemistry.
[6] M. Pasdar,et al. Design, synthesis, and anticancer activity of phosphonic acid diphosphate derivative of adenine-containing butenolide and its water-soluble derivatives of paclitaxel with high antitumor activity. , 2003, Bioorganic & medicinal chemistry.
[7] B. Aungst,et al. The Influence of Donor and Reservoir Additives on Caco-2 Permeability and Secretory Transport of HIV Protease Inhibitors and Other Lipophilic Compounds , 2000, Pharmaceutical Research.
[8] G. Amidon,et al. The Site-Specific Transport and Metabolism of Tacrolimus in Rat Small Intestine , 2003, Journal of Pharmacology and Experimental Therapeutics.
[9] H K Kroemer,et al. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. , 1999, The Journal of clinical investigation.
[10] G. Amidon,et al. Human Jejunal Permeability of Cyclosporin A: Influence of Surfactants on P-Glycoprotein Efflux in Caco-2 Cells , 2003, Pharmaceutical Research.
[11] Ronald T Borchardt,et al. A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P-glycoprotein activity in vitro. , 2002, Journal of pharmaceutical sciences.
[12] G. Amidon,et al. Tacrolimus is a class II low-solubility high-permeability drug: the effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats. , 2002, Journal of pharmaceutical sciences.
[13] J. H. Kou,et al. Effect of solubilizing excipients on permeation of poorly water-soluble compounds across Caco-2 cell monolayers. , 2000, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[14] U. S. Rao. Drug binding and nucleotide hydrolyzability are essential requirements in the vanadate-induced inhibition of the human P-glycoprotein ATPase. , 1998, Biochemistry.
[15] Adalberto Pessoa,et al. Micellar solubilization of drugs. , 2005, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
[16] J. Verweij,et al. Role of intestinal P-glycoprotein in the plasma and fecal disposition of docetaxel in humans. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[17] T. Murakami,et al. Role of organic anion transporting polypeptide 2 in pharmacokinetics of digoxin and beta-methyldigoxin in rats. , 2005, Journal of pharmaceutical sciences.
[18] Jochem Alsenz,et al. The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins. , 2003, Journal of pharmaceutical sciences.
[19] P. Artursson,et al. Epithelial transport of drugs in cell culture. VIII: Effects of sodium dodecyl sulfate on cell membrane and tight junction permeability in human intestinal epithelial (Caco-2) cells. , 1993, Journal of pharmaceutical sciences.
[20] Christopher J. H. Porter,et al. An in vitro examination of the impact of polyethylene glycol 400, pluronic P85, and vitamin E d-a-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine , 2002, AAPS PharmSci.
[21] Akira Yamamoto,et al. Modulation of intestinal P-glycoprotein function by cremophor EL and other surfactants by an in vitro diffusion chamber method using the isolated rat intestinal membranes. , 2004, Journal of pharmaceutical sciences.
[22] Paavo Honkakoski,et al. Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity. , 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[23] M Rowland,et al. Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia. , 2001, The Journal of pharmacology and experimental therapeutics.
[24] Lalitha Podila,et al. FUNCTIONAL ASSESSMENT OF MULTIPLE P-GLYCOPROTEIN (P-GP) PROBE SUBSTRATES: INFLUENCE OF CELL LINE AND MODULATOR CONCENTRATION ON P-GP ACTIVITY , 2005, Drug Metabolism and Disposition.
[25] P. Augustijns,et al. Biological, pharmaceutical, and analytical considerations with respect to the transport media used in the absorption screening system, Caco-2. , 2003, Journal of pharmaceutical sciences.
[26] Peter J. Meier,et al. Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties , 2004, Pflügers Archiv.
[27] O. Borgå,et al. The role of P-glycoprotein in limiting intestinal regional absorption of digoxin in rats. , 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[28] R. Borchardt,et al. Mechanistic roles of neutral surfactants on concurrent polarized and passive membrane transport of a model peptide in Caco-2 cells. , 1997, Journal of pharmaceutical sciences.
[29] T. Tsuruo,et al. Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells. , 1989, Cancer research.
[30] James E Polli,et al. Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers. , 2002, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[31] Y. Mine,et al. Surfactants Enhance the Tight-Junction Permeability of Food Allergens in Human Intestinal Epithelial Caco-2 Cells , 2003, International Archives of Allergy and Immunology.
[32] G. Szakács,et al. Functional Multidrug Resistance Protein (MRP1) Lacking the N-terminal Transmembrane Domain* , 1998, The Journal of Biological Chemistry.
[33] G R Wilkinson,et al. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. , 1999, Drug metabolism and disposition: the biological fate of chemicals.
[34] D. Thakker,et al. Rhodamine 123 Requires Carrier-Mediated Influx for Its Activity as a P-Glycoprotein Substrate in Caco-2 Cells , 2003, Pharmaceutical Research.
[35] Georges Houin,et al. Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo. , 2004, International journal of pharmaceutics.
[36] A. di Pietro,et al. Mutations in the chloride-bicarbonate exchanger gene AE1 cause autosomal dominant but not autosomal recessive distal renal tubular acidosis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[37] C Michael Stein,et al. “Inactive” excipients such as Cremophor can affect in vivo drug disposition , 2003, Clinical pharmacology and therapeutics.
[38] G. Houin,et al. Effect of Polyoxyl 35 Castor Oil and Polysorbate 80 on the Intestinal Absorption of Digoxin in vitro , 2000, Arzneimittelforschung.
[39] M. Cavet,et al. Evidence for a non-MDR1 component in digoxin secretion by human intestinal Caco-2 epithelial layers. , 2003, European journal of pharmacology.
[40] C. Porter,et al. Permeability assessment of poorly water-soluble compounds under solubilizing conditions: the reciprocal permeability approach. , 2006, Journal of pharmaceutical sciences.
[41] Lawrence X. Yu,et al. Vitamin E-TPGS Increases Absorption Flux of an HIV Protease Inhibitor by Enhancing Its Solubility and Permeability1 , 1999, Pharmaceutical Research.
[42] A. Ungell,et al. Effects of enzymatic inhibition and increased paracellular shunting on transport of vasopressin analogues in the rat. , 1992, Journal of pharmaceutical sciences.
[43] D. Ross,et al. Combinations of P-glycoprotein blockers, verapamil, PSC833, and cremophor act differently on the multidrug resistance associated protein (MRP) and on P-glycoprotein (Pgp). , 1999, Anticancer research.
[44] Yutaka Takahashi,et al. Common solubilizers to estimate the Caco-2 transport of poorly water-soluble drugs. , 2002, International journal of pharmaceutics.
[45] B. Harvey,et al. Rapid and non‐genomic reduction of intracellular [Ca2+] induced by aldosterone in human bronchial epithelium , 2001, The Journal of physiology.
[46] D. Mahoney,et al. Low‐Dose Methotrexate‐Induced Changes in Intestinal Permeability Determined by Polyethylene Glycol Polymers , 1989, Journal of Pediatric Gastroenterology and Nutrition - JPGN.
[47] Ming Yao,et al. Commonly used surfactant, Tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats , 2003, Archives of pharmacal research.
[48] G. Amidon,et al. Theoretical and experimental studies of transport of micelle-solubilized solutes. , 1982, Journal of pharmaceutical sciences.
[49] Gerd Mikus,et al. Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40 , 2003, Clinical pharmacology and therapeutics.