Contour-Assisted coiling with jailed microcatheter May result in better occlusion (CoCoJaMBO) in wide-necked intracranial aneurysms: Proof of principle and immediate angiographic results

Purpose Wide-necked bifurcation aneurysms, partially thrombosed, and recurrences of large and giant aneurysms are challenging to treat. We report our preliminary experience with a Contour-assisted coiling technique and discuss the periprocedural safety, feasibility, and effectiveness of the approach. Methods We retrospectively reviewed consecutive patients who received endovascular treatment for intracranial aneurysms with an intra-aneurysmal flow disruptor (Contour) at two neurovascular centres between October 2018 and December 2020 and identified patients treated with a combination of Contour and platinum coils. Clinical and procedural data were recorded. Results For this analysis, 8 patients (5 female) aged 60.1  ±  9.2 years on average were identified. Three of 8 aneurysms were associated with previous acute subarachnoid hemorrhage (SAH). The mean average dome height was 12.8  ±  7.6 mm, mean maximum dome width 10.3  ±  5.4 mm, and neck width 5.5  ±  2.5 mm. The mean dome-to-neck ratio was 1.9  ±  1.0. Immediate complete occlusion of the aneurysm was seen in 5 of 8 cases. In one SAH patient, a parent vessel was temporarily occluded but could be reopened rapidly. One device detached prematurely without any sequelae. No other procedural adverse events were recorded. Conclusion From this initial experience, Contour with adjunctive coiling is a safe and technically feasible method for endovascular treatment of large, wide-necked, partially thrombosed, recurrent, or ruptured bifurcation aneurysms. Further studies with larger numbers of patients and longer follow-up are needed to confirm our results.

[1]  J. Gauvrit,et al.  CLinical Assessment of WEB device in Ruptured aneurYSms (CLARYS): results of 1-month and 1-year assessment of rebleeding protection and clinical safety in a multicenter study , 2021, Journal of NeuroInterventional Surgery.

[2]  C. Mathys,et al.  eCLIPs bifurcation remodeling system for treatment of wide neck bifurcation aneurysms with extremely low dome-to-neck and aspect ratios: a multicenter experience , 2020, Journal of NeuroInterventional Surgery.

[3]  R. Pranata,et al.  Efficacy and safety of PulseRider for treatment of wide-necked intracranial aneurysm—A systematic review and meta-analysis , 2020, Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences.

[4]  A. Molyneux,et al.  Aneurysm treatment with WEB in the cumulative population of two prospective, multicenter series: 3-year follow-up , 2020, Journal of NeuroInterventional Surgery.

[5]  O. Ganslandt,et al.  Use of the pCONus HPC as an adjunct to coil occlusion of acutely ruptured aneurysms: early clinical experience using single antiplatelet therapy , 2020, Journal of NeuroInterventional Surgery.

[6]  C. Bleise,et al.  The Contour—Early Human Experience of a Novel Aneurysm Occlusion Device , 2020, Clinical Neuroradiology.

[7]  T. Patankar,et al.  Endovascular treatment of wide-necked intracranial aneurysms using the novel Contour Neurovascular System: a single-center safety and feasibility study , 2020, Journal of NeuroInterventional Surgery.

[8]  J. Mocco,et al.  Stent-assisted coiling of cerebral aneurysms: multi-center analysis of radiographic and clinical outcomes in 659 patients , 2019, Journal of NeuroInterventional Surgery.

[9]  I. Saatci,et al.  The safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide-necked bifurcation aneurysms: final 12-month results of the pivotal WEB Intrasaccular Therapy (WEB-IT) Study , 2019, Journal of NeuroInterventional Surgery.

[10]  M. Sluzewski,et al.  The Woven EndoBridge (WEB) for recurrent aneurysms: Clinical and imaging results , 2018, Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences.

[11]  C. Kabbasch,et al.  Factors that determine aneurysm occlusion after embolization with the Woven EndoBridge (WEB) , 2018, Journal of NeuroInterventional Surgery.

[12]  P. Lylyk,et al.  Treatment of Wide-Necked Bifurcation Aneurysms , 2018, Clinical Neuroradiology.

[13]  P. Lylyk,et al.  The pCONus2 Neck-Bridging Device: Early Clinical Experience and Immediate Angiographic Results. , 2017, World neurosurgery.

[14]  T. Patankar,et al.  WEB in Partially Thrombosed Intracranial Aneurysms: A Word of Caution , 2016, American Journal of Neuroradiology.

[15]  C. Kabbasch,et al.  WEB as part of a multimodality treatment in complex, large, and partially thrombosed intracranial aneurysms: a single-center observational study of technical success, safety, and recurrence , 2016, Journal of NeuroInterventional Surgery.

[16]  J. Gauvrit,et al.  WEB-DL Endovascular Treatment of Wide-Neck Bifurcation Aneurysms: Long-Term Results in a European Series , 2015, American Journal of Neuroradiology.

[17]  G. Duckwiler,et al.  Interobserver variability in the assessment of aneurysm occlusion with the WEB aneurysm embolization system , 2014, Journal of NeuroInterventional Surgery.

[18]  Aman B Patel,et al.  An update to the Raymond–Roy Occlusion Classification of intracranial aneurysms treated with coil embolization , 2014, Journal of NeuroInterventional Surgery.

[19]  T. Terada,et al.  Hemodynamics of 8 Different Configurations of Stenting for Bifurcation Aneurysms , 2013, American Journal of Neuroradiology.

[20]  Raphaël Blanc,et al.  Stent-Assisted Coiling of Intracranial Aneurysms: Clinical and Angiographic Results in 216 Consecutive Aneurysms , 2010, Stroke.