Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP.

[1]  M. Sporn,et al.  Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression , 2008, Arthritis research & therapy.

[2]  C. Brinckerhoff,et al.  Diesel Exhaust Particles Activate the Matrix-Metalloproteinase-1 Gene in Human Bronchial Epithelia in a β-Arrestin–Dependent Manner via Activation of RAS , 2008, Environmental health perspectives.

[3]  T. Sorsa,et al.  Effect of MMP-1 promoter polymorphisms on GCF MMP-1 levels and outcome of periodontal therapy in patients with severe chronic periodontitis. , 2008, Journal of clinical periodontology.

[4]  S. Duffy,et al.  Matrix Metalloproteinase Single-Nucleotide Polymorphisms and Haplotypes Predict Breast Cancer Progression , 2007, Clinical Cancer Research.

[5]  M. Sporn,et al.  Regulation of matrix metalloproteinase gene expression by a retinoid X receptor-specific ligand. , 2007, Arthritis and rheumatism.

[6]  C. Brinckerhoff,et al.  Molecular targets in osteoarthritis: metalloproteinases and their inhibitors. , 2007, Current drug targets.

[7]  M. C. Santos,et al.  Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population. , 2006, Journal of clinical periodontology.

[8]  M. Vincenti,et al.  Interleukin‐1 beta induction of matrix metalloproteinase‐1 transcription in chondrocytes requires ERK‐dependent activation of CCAAT enhancer‐binding protein‐beta , 2006, Journal of cellular physiology.

[9]  C. Brinckerhoff,et al.  Short hairpin RNA-mediated inhibition of matrix metalloproteinase-1 in MDA-231 cells: effects on matrix destruction and tumor growth. , 2005, Cancer research.

[10]  D. Tregouet,et al.  Haplotype Effect of the Matrix Metalloproteinase-1 Gene on Risk of Myocardial Infarction , 2005, Circulation research.

[11]  E. Nexo,et al.  Real-time polymerase chain reaction is a sensitive and precise method for quantifying transcription from reporter plasmids , 2004, Scandinavian journal of clinical and laboratory investigation.

[12]  R. Kudo,et al.  A relationship between Matrix metalloproteinase-1 (MMP-1) promoter polymorphism and cervical cancer progression. , 2003, Cancer letters.

[13]  S. Ye,et al.  Variation in the matrix metalloproteinase-1 gene and risk of coronary heart disease. , 2003, European heart journal.

[14]  C. Brinckerhoff,et al.  Potential for the 2G single nucleotide polymorphism in the promoter of matrix metalloproteinase to enhance gene expression in normal stromal cells. , 2002, Cancer research.

[15]  Constance E. Brinckerhoff,et al.  Matrix metalloproteinases: a tail of a frog that became a prince , 2002, Nature Reviews Molecular Cell Biology.

[16]  S. Bronson,et al.  Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation , 2001, BMC biotechnology.

[17]  C. Brinckerhoff,et al.  IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways. , 2001, Nucleic acids research.

[18]  柴沼 質子 Real-Time RT-PCR法の応用例について , 2001 .

[19]  V. Quesada,et al.  Identification and Enzymatic Characterization of Two Diverging Murine Counterparts of Human Interstitial Collagenase (MMP-1) Expressed at Sites of Embryo Implantation* , 2001, The Journal of Biological Chemistry.

[20]  Y. Liu,et al.  Yeast Nuclear Extract Contains Two Major Forms of RNA Polymerase II Mediator Complexes* , 2001, The Journal of Biological Chemistry.

[21]  J. Pelletier,et al.  Peroxisome proliferator--activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes. , 2001, Arthritis and rheumatism.

[22]  I. Day,et al.  Invasiveness of cutaneous malignant melanoma is influenced by matrix metalloproteinase 1 gene polymorphism. , 2001, Cancer research.

[23]  D. Brenner,et al.  Analysis of ferrochelatase expression during hematopoietic development of embryonic stem cells. , 2000, Blood.

[24]  W. Aird,et al.  Targeting the Hprt locus in mice reveals differential regulation of Tie2 gene expression in the endothelium. , 2000, Physiological genomics.

[25]  W. Aird,et al.  Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expression. , 2000, Physiological genomics.

[26]  C. Sigmund,et al.  Appropriate Tissue- and Cell-specific Expression of a Single Copy Human Angiotensinogen Transgene Specifically Targeted Upstream of the HPRT Locus by Homologous Recombination* , 2000, The Journal of Biological Chemistry.

[27]  Y. Nakamura,et al.  Correlation between expression of the matrix metalloproteinase-1 gene in ovarian cancers and an insertion/deletion polymorphism in its promoter region. , 1999, Cancer research.

[28]  P. Hasty,et al.  Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice. , 1999, BioTechniques.

[29]  J. Gusella,et al.  A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription. , 1998, Cancer research.

[30]  Makoto Sato,et al.  Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts , 1997, Cell.

[31]  N. Maeda,et al.  Single-copy transgenic mice with chosen-site integration. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[32]  Y. Okada,et al.  Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis , 1995, Molecular and cellular biology.

[33]  Y. Okada,et al.  Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema , 1992, Cell.

[34]  H. S. Kim,et al.  Cotransformation and gene targeting in mouse embryonic stem cells , 1991, Molecular and cellular biology.

[35]  N. Nakatsuji,et al.  Establishment of the Embryo‐derived Stem (ES) Cell Lines from Mouse Blastocysts: Effects of the Feeder Cell Layer. , 1987, Development, growth & differentiation.

[36]  J. D’Armiento,et al.  Identification of a cigarette smoke-responsive region in the distal MMP-1 promoter. , 2009, American journal of respiratory cell and molecular biology.

[37]  David Bouchez,et al.  Manipulating the Mouse Embryo , 2007 .

[38]  C. Brinckerhoff,et al.  Matrix metalloproteinases: role in arthritis. , 2006, Frontiers in bioscience : a journal and virtual library.